维生素C在呼吸道感染中应用的研究进展

doi:10.3760/cma.j.issn.1007-1245.2023.23.003

摘要/Abstract

摘要：

近年来，维生素C在呼吸道感染等疾病的辅助治疗中被广泛应用，但其有效性却备受质疑。本文探讨了维生素C对呼吸系统感染性疾病的影响，查阅相关文献梳理了其作用机制、给药剂量以及不良反应。数十年来，大量研究证实，维生素C通过减弱氧化应激、降低炎性反应、调节免疫、改善循环、抗病原微生物、保护肺脏等作用，对呼吸道感染性疾病预防及治疗具有一定影响。有研究表明，应用维生素C对疾病治疗可能无明显效果。年龄、体质量、性别等因素均可能影响维生素C的需求量。自维生素C问世以来，大量动物模型实验及临床研究报道了其在感染性疾病中的有效性，且具有安全性较高、价格低廉、百姓熟知等特点，不应否定维生素C的临床价值。

关键词:

呼吸道感染, 炎症, 维生素C, 抗坏血酸, 进展

Abstract:

In recent years, vitamin C has been widely used in the adjuvant treatment of diseases such as respiratory tract infection, but its effectiveness has been questioned. This paper discusses the effect of vitamin C on respiratory infectious diseases, and reviews its mechanism of action, dosage, and adverse reactions. For decades, a large number of studies have confirmed that vitamin C has a certain impact on the prevention and treatment of respiratory infectious diseases by reducing oxidative stress, reducing inflammatory response, regulating immunity, improving circulation, resisting pathogenic microorganisms, and protecting lung. Some studies have shown that the application of vitamin C may have no significant effect on disease treatment. Age, weight, gender, and other factors may affect the demand for vitamin C. Since the advent of vitamin C, a large number of animal model experiments and clinical studies have reported its effectiveness in infectious diseases, and it has the characteristics of high safety, low price, and familiar to the people. The clinical value of vitamin C should not be denied.

Key words:

Respiratory tract infection, Inflammation, Vitamin C, Ascorbic acid, Progress

肖曦　石斗飞.

维生素C在呼吸道感染中应用的研究进展 [J]. 国际医药卫生导报, 2023, 29(23): 3330-3335.

Xiao Xi, Shi Doufei.

Research progress on the application of vitamin C in respiratory tract infection [J]. International Medicine and Health Guidance News, 2023, 29(23): 3330-3335.

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