Objective　To explore the effect of Fuyang jar warm moxibustion and scraping therapy combined with auricular acupuncture point seed implantation for patients with post-stroke insomnia. Methods　Ninety patients with post-stroke insomnia treated at Liangyungang Hospital of Traditional Chinese Medicine from June 2021 to March 2025 were selected as the study objects, and were divided in a control group and an observation group according to the intervention methods, with 45 cases in each group. There were 23 males and 22 females in the control group; they were (65.02±5.09) years old; there were 28 cases of ischemic stroke and 17 cases of hemorrhagic stroke; their score of National Institutes of Health Stroke Scale (NIHSS) was 12.34±3.16. There were 24 males and 21 females in the observation group; they were (64.78±5.27) years old; there were 26 cases of ischemic stroke and 19 cases of hemorrhagic stroke; their score of NIHSS was 11.83±3.02. The control group received Fuyang jar warm moxibustion and scraping therapy; in addition, the observation group were treated with auricular acupuncture point seed implantation. The levels of anxiety and depression, sleep quality, and the incidence rates of adverse reactions were compared between the two groups. t and χ² tests were used for the statistical comparisons. Results　After the intervention, the scores of Self-Rating Depression Scale (SDS) and Self-Rating Anxiety Scale (SAS), sleep latency, rapid eye movement (REM) sleep time, and score of Pittsburgh Sleep Quality Index (PSQI) in the observation group were higher than those in the control group [38.19±5.43 vs. 42.36±6.84, 34.35±6.12 vs. 40.68±7.54, (27.54±4.24) min vs. (31.98±3.61) min, (79.55±5.69) min vs. (94.17±5.25) min, and 8.99±3.50 vs. 11.08±4.67], and the total sleep time was longer [(7.99±0.50) h vs. (6.28±0.67) h, with statistical differences (all P<0.05). There was no statistical difference in the incidence rate of adverse reactions between the observation group and the control group [22.22% (10/45) vs. 20.00% (9/45); χ²=0.067; P=0.796]. Conclusion　Fuyang jar warm moxibustion and scraping therapy combined with auricular acupuncture point seed implantation for patients with post-stroke insomnia can alleviate their anxiety and depression and improve their quality of sleep, and does not increase the incidence rate of adverse reactions.

Objective　To investigate the levels of lipoprotein-associated phospholipase A2 (Lp-PLA2) and soluble growth stimulating expression factor-2 (sST-2) and their correlation with cardiac function and inflammatory factors in patients with coronary heart disease and heart failure. Methods　A total of 85 patients with coronary heart disease (including 41 patients with heart failure) diagnosed and treated in Qidong Second People's Hospital from January 2024 to May 2025 were selected as the study objects. The general data, levels of Lp-PLA2 and sST-2, cardiac function indicators [left ventricular ejection fraction (LVEF), cardiac output (CO), left ventricular end-systolic diameter (LVESD), and left ventricular end-diastolic diameter (LVEDD)], and inflammatory factors [neutrophil count (NEUT), procalcitonin (PCT), and heparin-binding protein (HBP)] were compared between the patients complicated with heart failure and the patients with only coronary heart disease. The Pearson correlation coefficient was used to analyze the levels of Lp-PLA2 and sST-2 in the patients with coronary heart disease and heart failure, as well as their correlation with cardiac function and inflammatory factors. Statistics were performed using t-test, χ² test, and Pearson correlation analysis. Results　There were no statistical differences in the general data between the two groups (all P>0.05). The levels of Lp-PLA2, sST-2, NEUT, PCT, and HBP, LVESD, and LVEDD in the heart failure group were higher than those in the simple coronary heart disease group, and the LVEF and CO were lower (all P<0.05). The NEUT, PCT and HBP in the heart failure group were significantly higher than those in the simple coronary heart disease group (all P<0.05). The Pearson correlation analysis showed that the levels of Lp-PLA2 and sST-2 were positively correlated with LVESD, LVEDD, NEUT, PCT, and HBP (r=0.708, 0.594, 0.401, 0.412, 0.328, 0.732, 0.610, 0.419, 0.448, and 0.357), and negatively with LVEF and CO (r=-0.694, -0.525, -0.718, and -0.573) in the patients with heart failure. Conclusion　The expression of Lp-PLA2 and sST-2 in patients with coronary heart disease and heart failure is further increased, and their levels are correlated with cardiac function and inflammatory factors.

Objective　To investigate the effect of liposomal bupivacaine (LB) as a local anesthetic for nerve block on postoperative nausea and vomiting (PONV) in patients undergoing laparoscopic atypical hepatectomy. Methods　Ninety-six patients who underwent laparoscopic atypical hepatectomy at Xiamen Branch, Zhongshan Hospital, Fudan University between January and March 2025 were selected for the randomized controlled trial. The patients were divided into a control group and a study group by the random number table method, with 48 cases in each group. The control group consisted of 26 males and 22 females; they were (52.90±13.67) years old; their body mass index (BMI) was (22.92±3.26) kg/m². The study group consisted of 34 males and 14 females; they were (53.81±14.13) years old; their BMI was (23.61±3.77) kg/m². The study group received ultrasound-guided nerve block with LB and general anesthesia, while the control group received general anesthesia alone. The incidence rates and frequencies (graded according to it) of PONV 48 h after the operation, total intraoperative opioid consumptions, operation times, postoperative hospitalization times, and perioperative anesthesia satisfaction were compared between the two groups. Statistical analyses were performed using the t, χ², and rank-sum tests. Results　The total number of PONV episodes in the study group was significantly lower than that in the control group (4 times vs. 17 times), with a statistical difference (P<0.05). All the 4 PONV episodes in the study group were grade Ⅰ, and the 17 PONV episodes in the control group were grades Ⅰ-Ⅳ, with a statistical difference (P<0.01). The total intraoperative sufentanil consumption in the study group was less than that in the control group [(30.08±10.30) μg vs. (48.71±13.99) μg], with a statistical difference (P<0.01). There were no statistical differences between the two groups in the time to first ambulation, postoperative hospitalization time, and operation time (all P>0.05). The patient satisfaction with analgesic effect in the study group was higher than that in the control group [97.9% (47/48) vs. 85.4% (41/48)], with a statistical difference (P<0.05). Conclusion　The use of LB as a local anesthetic for nerve block in the perioperative period of laparoscopic atypical hepatectomy not only can improve the patient satisfaction with perioperative anesthesia, but also can reduce the usage of intraoperative opioid and the incidence of PONV.

Objective　To explore the predictive value of uterine artery blood flow parameters combined with echocardiography for early-onset preeclampsia (PE). Methods　A retrospective study was conducted to collect the data of 90 patients with early-onset PE admitted to Shangluo Central Hospital from June 2022 to August 2024. The patients were included in a case group [age 21-45 (30.21±4.17) years]. In addition, the data of 90 healthy pregnant women who received regular prenatal examination in the hospital during the same period were collected according to the ratio of 1:1 and included in a control group [age 20-45 (29.32±4.45) years]. The uterine artery blood flow parameters [resistance index (RI), pulsatility index (PI), and systolic phase/diastolic phase (S/D)] and echocardiographic parameters [left ventricular ejection fraction (LVEF), fractional shortening (FS), cardiac index (CI), and early diastolic flow velocity/late diastolic flow velocity (E/A)] were collected and compared between the two groups at 14-20 weeks of gestation. The measurement data were of the normal distribution, and the independent sample t test was used to test the differences between the groups. The Mann-Whitney U test was used to test the difference between the groups. The χ² test was used to test the differences between the groups. The receiver operating characteristic curve (ROC) and the area under the curve (AUC) were used to evaluate the predictive value of uterine artery blood flow parameters combined with echocardiography for early onset PE. Results　The RI, PI, and S/D in the case group were all higher than those in the control group (0.84±0.25 vs. 0.68±0.13, 1.08±0.29 vs. 0.86±0.17, and 2.60±0.58 vs. 2.12±0.25), and the LVEF, E/A values were lower [(61.58±5.74)% vs. (66.44±6.02)%, and 0.93±0.22 vs. 1.17±0.36], with statistical differences (all P<0.05). The ROC showed that the combined prediction of AUC for early-onset PE by logistic regression probability models of RI, PI, S/D, LVEF, E/A alone and several at 14-20 weeks of pregnancy was greater than 0.7 (95%CI 0.914-0.975 for joint prediction), which had certain predictive value, and the joint prediction value was higher than those of RI, PI, S/D, LVEF, and E/A alone (P<0.05). Conclusion　Uterine artery blood flow parameters (RI, PI, and S/D) and echocardiographic parameters (LVEF and E/A) have certain predictive value for early-onset PE, and the combined predictive value is higher.

Objective　To investigate the effect of intermittent pneumatic compression (IPC) combined with anticoagulants in the prevention of deep venous thrombosis of lower extremity in patients after cesarean section. Methods　Ninety-six pregnant women undergoing cesarean section in Yan'an City Hospital of Traditional Chinese Medicine from July 2021 to June 2022 were included in the study, and were divided into a combination group and an anticoagulation group according to the treatment plans, with 48 cases in each group. The combination group were (28.98±3.81) years old, and had delivered (0.98±0.23) times. The the anticoagulation group were (29.52±4.06) years old, and had delivered (1.04±0.29) times. The anticoagulation group subcutaneously injected low molecular weight heparin sodium after cesarean section; in addition, the combination group took IPC. The incidences of venous thrombosis of lower extremity, perioperative coagulation function [prothrombin time (PT), thrombin time (TT), D-dimer (D-D), and fibrinogen (FIB)], hemorheology indicators [plasma viscosity (PV), high shear viscosity (HBV) of whole blood, and erythrocyte deformity-index (EDI)], and surgery-related indicators (postoperative exhaust time, postoperative off-bed time, and lower limb pain) were compared between the two groups. t test, repeated measure analysis of variance, and Fisher exact probability method were used for statistical comparisons. Results　The incidence rate of venous thrombosis of lower extremity in the combination group was 0, and that in the anticoagulation group 4.17% (2/48), with no statistical difference (P=0.495). Five days after the surgery, the PT and TT were higher than those before the surgery in both groups, and the levels of D-D and FIB were lower; the PT, TT, and levels of D-D and FIB in the combination group were better than those in the anticoagulation group [(13.29±1.27) s vs. (12.67±1.62) s, (15.04±1.09) s vs. (14.38±1.17) s, (1.74±0.32) mg/L vs. (2.41±0.53) mg/L, and (4.39±0.51) g/L vs. (5.01±0.48) g/L], with statistical differences (all P<0.05). Five days after the surgery, the PV, HBV, and EDI were higher than those before the surgery in both groups; the PV and HBV in the combination group were lower than those in the anticoagualation group [(1.92±0.44) mPa/s vs. (2.17±0.51) mPa/s and (4.81±0.51) mPa/s vs. (5.12±0.57) mPa/s], and the EDI was higher (1.29±0.23 vs. 1.06±0.21), with statistical differences (all P<0.05). The postoperative exhaust time and off-bed time in the combination group were shorter than those in the anticoagulation group [(17.63±1.85) h vs. (20.17±1.73) h and (24.25±2.53) h vs. (31.88±2.46) h], and the score of Visual Analogue Scale was lower (1.27±0.45 vs. 2.08±0.28), with statistical differences (all P<0.05). Conclusion　PIC combined with anticoagulants can effectively improve the coagulation function and hemodynamics of parturients after cesarean section, effectively prevent the formation of deep venous thrombosis of lower extremity, and promote their recovery.

Objective　To analyze the clinical effect of predeposit and intraoperative autologous blood transfusion in women with high hemorrhagic risk taking cesarean section. Methods　One hundred and eighty-four high-risk pregnant women undergoing cesarean section at Hanzhong Central Hospital between October 2016 and August 2024 were selected as the study objects. Based on the transfusion methods, the women were divided into a control group and an observation group, with 92 cases in each group. The control group were (32.54±4.25) years old, and received conventional allogeneic transfusion. The observation group were (32.21±4.66) years old, and received autologous transfusion with predeposit and intraoperative autologous blood. The coagulation parameters [activated partial thromboplastin time (APTT), prothrombin time (PT), fibrinogen (FIB), and activated clotting time (ACT)], white blood cell counts, neutrophil percentages, lymphocyte percentages, oxygenation indicators [arterial oxygen partial pressure (PaO₂) and mixed venous oxygen saturation (SvO₂)], and incidence rates of adverse reactions were compared between the groups. Statistical analysis was performed using t and χ² tests. Results　After the transfusion, there was no statistical difference in the FIB level between the two groups (P>0.05); the APTT, PT, and ACT in the observation group were shorter than those in the control group [(34.78±2.71) s vs. (35.83±2.14) s, (15.82±2.25) s vs. (16.69±2.18) s, and (120.54±24.52) s vs. (129.32±25.23) s], with statistical differences (t=2.917, 2.664, and 2.394; all P<0.05). The white blood cell count and neutrophil percentage in the observation group were lower than those in the control group [(9.25±1.36)×10⁹ vs. (10.41±1.55)×10⁹ and (70.28±2.57)% vs.(72.30±2.61)%], while the lymphocyte percentage was higher [(5.96±1.04)% vs. (5.44±1.02)%], with statistical differences (t=5.396, 5.290, and 3.424; all P<0.05). Both PaO₂ and SvO₂ in the observation group were higher than those in the control group [(124.41±18.57) mmHg vs. (113.85±17.46) mmHg (1 mmHg=0.133 kPa) and (87.21±5.57)% vs. (84.13±4.32)%], with statistical differences (t=3.974 and 4.191; both P<0.05). There was no statistical difference in the incidence rate of adverse reactions between the observation group and the control group [8.70% (8/92) vs. 14.13% (13/92); P>0.05]. Conclusion　Predeposit and intraoperative autologous blood transfusion can significantly enhance coagulation function and oxygenation status while attenuating the inflammatory response in women with high hemorrhagic risk taking cesarean section, without increasing adverse events.

Objective　To analyze the epidemic patterns and pathogenic characteristics of influenza viruses in Haizhu District from 2021 to 2024, and to provide scientific basis and technical support for formulating influenza prevention and control measures. Methods　From March 2021 to December 2024, 5 120 throat swab samples from influenza-like cases were sent for nucleic acid testing in the Huizhou District Center for Disease Control and Prevention. The number of male samples tested was 2 698, and the number of female samples tested was 2 422. The age ranged from 1 day to 98 years old. The detection rates of influenza A/B viruses in the samples were analysed, and the population and seasonal distribution characteristics of different types of influenza viruses were compared. The statistical methodology employed the χ² test and the Bonferroni method for multiple comparisons. Results　A total of 5 120 throat swab samples were tested, and 2 578 samples were found to be positive for the influenza virus. The positive detection rate was 50.34%. Among them, the positive detection rate of influenza A was 68.11% (1 756/2 578), and the positive detection rate of influenza B was 31.89% (822/2 578). The predominant infection was caused by the influenza A virus, especially in 2023, when the positive detection rate of the influenza A virus reached as high as 75.12%. The positive detection rates in winter [63.86% (569/891)] and in spring [62.17% (1 047/1 684)] were both higher than those in summer and autumn. There was a statistically significant difference in the positive detection rate of influenza viruses between different seasons (χ²=1 313.806, P<0.001). The detection results of different seasonal influenza virus subtypes were analyzed. The proportion of type A (H1N1) influenza virus was the highest in spring (77.9%), while the detection rate of type A (H3N2) virus was higher in winter (37.65%). In autumn, there was a dual dominant trend of type A (H3N2) and type B (Victoria) subtypes, and the difference was statistically significant (χ²=490.000, P<0.001). The positive detection rates for males and females in the test samples were 50.22% (1,355/2,698) and 50.50% (1,223/2,422), respectively. For 939 of the samples, subtype detection of the influenza virus was conducted. The results showed that among all the subtypes, the detection rate of influenza subtypes in males was higher than that in females, and the difference was statistically significant (χ²=214.892, P<0.001). The highest positive detection rate of influenza virus nucleic acid was observed in the age group of 5 to <15 years old, with a detection rate of 73.55% (2 077/2 824), while the detection rate for the elderly in the ≥60-year-old age group was the lowest, only 8.14% (31/381). The detection rates of influenza A in all age groups were higher than those of influenza B. There was a statistically significant difference in the positive detection rate of influenza viruses between different age groups (χ²=12.095, P=0.017). The positive detection rate of influenza virus of the student group was higher than those of other groups. There was a statistically significant difference in the detection rate between different occupations (χ²=2 157.191, P<0.001). Conclusions　At the Haizhu District of Guangzhou City, the dominant influenza strains showed seasonal alternation in their prevalence from 2021 to 2024. The prevalence of type A influenza was generally higher than that of type B influenza. The detection rate was higher among children aged 5 to <15 years old and students. Continuous influenza pathogen monitoring should be carried out in schools. Through vaccination and health education measures, the monitoring and prevention of influenza outbreaks in kindergartens and primary and secondary schools should be strengthened.

Objective　To evaluate the therapeutic efficacy of Jiawei Danggui Shaoyao San combined with epalrestat tablets in the treatment of diabetic peripheral neuropathy (DPN) in elderly patients. Methods　A prospective study was conducted on 120 elderly DPN patients treated at Shangluo Central Hospital from January 2021 to January 2023. Using a convenience sampling method, the patients were divided into an experimental group (60 cases) and a control group (60 cases). In the control group, there were 29 males and 31 females, with an age of (69.14±4.31) years; in the experimental group, there were 30 males and 30 females, with an age of (69.39±4.26) years. The control group received epalrestat tablets, while the experimental group received Jiawei Danggui Shaoyao San and epalrestat. The treatment duration was 3 months. The TCM syndrome scores, EMG indicators of lower limbs [sensory nerve conduction velocity(SCV) and motor nerve conduction velocity(MCV)], blood glucose status [fasting plasma glucose (FPG), 2-hour postprandial glucose (2 hPG), and glycated hemoglobin(HbA1c)], neuropathy [Michigan Diabetic Neuropathy Score(MDNS) score and Toronto Clinical Scoring System(TCSS) score], oxidative stress [malondialdehyde(MDA) and superoxide dismutase(SOD)], serum levels [brain-derived neurotrophic factor(BDNF), nitric oxide(NO), endothelin-1 (ET-1), and ficolin-3], and adverse reactions were compared between the two groups. Statistical methods employed t test and χ² test. Results　After the treatment, the scores of main syndrome, secondary syndrome, MDNS, and TCSS, FPG, HbA1 c, 2 hPG, MDA, ET-1, and ficolin-3 in the experimental group were lower than those in the control group [2.19±0.37 vs. 5.24±0.85, 1.39±0.28 vs. 2.86±0.47, 13.67±2.18 vs. 17.11±2.79, 6.03±0.78 vs. 7.91±0.93, (5.08±0.66) mmol/L vs. (7.02±1.20) mmol/L, (6.77±0.92)% vs. (7.22±1.03)%, (9.13±1.61) mmol/L vs. (12.22±2.64) mmol/L, (2.48±1.75) U/ml vs. (4.19±1.82) U/ml, (24.41±3.87) ng/L vs. (34.73±4.32) ng/L, and (9.71±2.62) μg/L vs. (12.45±3.70) μg/L], and the SCV of sural nerve, MCV of common peroneal nerve, and levels of SOD, BDNF, and NO were higher [(43.01±4.13) m/s vs. (38.65±3.81) m/s, (51.91±4.91) m/s vs. (46.45±3.35) m/s, (133.21±12.33) U/ml vs. (121.31±18.03) U/ml, (6.17±0.71) ng/L vs. (4.25±0.36) ng/L, and (3.96±0.72) μmol/L vs. (3.34±0.63) μmol/L], with statistical differences (all P<0.05). The incidence rate of adverse reactions in the experimental group was lower than that in the control group [3.33%(2/60) vs. 16.67%(10/60)], with a statistical difference (χ²=5.926; P=0.015). Conclusions　Jiawei Danggui Shaoyao San combined with epalrestat tablets in the treatment of elderly patients with DPN can effectively improve their symptoms and neurological function, regulate blood glucose, reduce the degree of neuropathy, improve the level of antioxidant and regulatory factors, and have high safety.

Objective　To investigate the effect of bezafibrate in the treatment of lipoprotein lipase deficiency (LPLD) and its potential molecular mechanisms. Methods　A case of LPLD caused by compound heterozygous mutations (c.3G>C and c.835_836delCT) in the lipoprotein lipase (LPL) gene was reported. The clinical data, treatment response, and follow-up data were analyzed. Molecular docking simulations of bezafibrate with both the wild-type and mutant LPL were performed using the AutoDock Vina software, and binding conformations were visualized using PyMol. Results　After the treatment with bezafibrate, the triglyceride level in the patient decreased by 63.7%. The molecular docking showed that bezafibrate binded to the polypeptide "lid" domain and adjacent regions of the mutant LPL, with a binding energy of -5.305 kcal/mol, potentially inducing conformational changes that partially restore enzyme function. Additionally, as a pan-PPAR agonist, bezafibrate synergistically lowered the lipids activating the PPARα, β, and γ pathways. Conclusions　Bezafibrate demonstrates significant efficacy for patients with LPLD. Its mechanism may be related to direct modulation of mutant LPL activity and systemic activation of PPAR pathways.

Objective　To investigate the current status of fear and its influencing factors in patients before gastrointestinal endoscopy, and to provide a basis for developing targeted psychological interventions. Methods　A total of 528 patients scheduled for gastrointestinal endoscopy at Guangdong Second Provincial General Hospital between May and December 2024 were selected by the convenient sampling method for the cross-sectional survey. Their demographic data were collected. The Self-Rating Anxiety Scale (SAS) and Fear of Progression Questionnaire-Short Form (FoP-Q-SF) were used to assess their anxiety levels and fear of disease progression. The Pearson correlation analysis and multiple linear regression analysis were utilized to identify the influencing factors. Results　The total FoP-Q-SF score was 23.22±10.39. Notably, 16.90% of the patients exhibited a high level of fear (FoP-Q-SF score≥34). The univariate analysis revealed significantly higher fear levels in the females, patients who were 18-30 years old, unmarried individuals, and patients with chronic diseases (all P<0.05). The total SAS score was positively correlated with the total FoP-Q-SF score (r=0.745, P<0.01). The multiple linear regression analysis identified the history of chronic diseases (β= 0.050, P=0.017) and anxiety level (β=0.721, P < 0.001) as the independent predictors of fear. Conclusions　Fear is prevalent among patients before gastrointestinal endoscopy and is influenced by anxiety levels, history of chronic diseases, and specific demographic characteristics (female gender and being 18-30 years old). Implementing stratified interventions targeting high-risk groups is warranted. These interventions should focus on cognitive restructuring, anxiety management, and reframing disease perceptions to enhance procedural adherence and improve the overall healthcare experience.

Objective　To evaluate the clinical efficacy of the goal-oriented progressive nursing model in the rehabilitation process of elderly patients with vertebral compression fractures, as well as its impact on the quality of life of these patients. Methods　A prospective randomized controlled study was conducted, including 120 elderly patients with lumbar vertebral compression fractures who were treated at Ankang Hospital of Traditional Chinese Medicine from April 2023 to March 2024. They were divided into an observation group and a control group by the random number table method, with 60 cases in each group. The observation group had 28 males and 32 females, with an age of (72.5±6.3) years and a disease duration of (3.2±1.4) months. The control  group had 26 males and 34 females, with an age of (73.1±6.5) years and a disease duration of (3.4±1.5) months. The control group received routine nursing measures, while the observation group was given the additional targeted and stepwise nursing intervention plan on top of the routine measures. Both groups were intervened for 8 weeks. The Visual Analogue Scale (VAS) scores, Activities of Daily Living (ADL) scores, as well as the incidence rates of complications and nursing satisfaction before and after the intervention in the two groups were compared. Statistical methods employed t-test and χ² test. Results　After the intervention, the VAS score of the observation group was lower than that of the control group [(3.1±0.8) points vs. (4.5±1.0) points], and the ADL score was higher than that of the control group [(45.8±5.1) points vs. (38.6±4.8) points], with statistical differences(t=8.526 and 7.843; both P<0.05). The total incidence rate of complications in the observation group was lower than that in the control group [6.7% (4/60) vs. 20.0% (12/60)], and the nursing satisfaction rate was higher [96.7% (58/60) vs. 83.3% (50/60)], with statistical differences were statistically significant (χ²=4.385 and 5.926; both P<0.05). Conclusions　The goal-oriented progressive nursing mode can effectively alleviate the pain of elderly patients with lumbar vertebral compression fractures, enhance their ability to take care of daily life, reduce the incidence of related complications, and increase their satisfaction with the nursing services. It has high clinical promotion value.

Objective　To explore the application effect of perineal massage with birthing ball combined with full-time doula companionship during labor in parturients. Methods　A prospective study was conducted on 98 parturients who delivered at the Women and Children's Hospital of Zhumadian Central Hospital from November 2021 to November 2023. They were randomly divided into two groups, with 49 cases in each group. The control group were 23 to 37 (30.56 ± 2.12) years old, and received routine care. The observation group were 23 to 37 (30.59 ± 2.14) years old. They were given perineal massage with a birthing ball combined with full-time doula accompaniment during the delivery process. The effects of labor analgesia, psychological state, comfort levels, progress of labor, incidence rates of adverse labor outcomes, and maternal satisfaction were compared between the two groups. Statistical methods employed t-test and χ² test. Results　The Visual Analogue Scale (VAS) scores for the first, second, and third stages of labor in the observation group were all lower than those in the control group [(1.49±0.54) points vs. (3.56 ±0.67) points, (3.53±1.01) points vs. (8.68±0.52) points, and (2.79±0.64) points vs. (4.46±1.03) points], and the differences were statistically significant (t=16.839, 31.734, and 9.640, all P<0.05). The scores of the Hamilton Anxiety Scale (HAMA) and the Edinburgh Postnatal Depression Scale (EPDS) in the observation group were lower than those in the control group 2 days after delivery [(9.91±2.04) points vs. (14.42±2.18) points and (2.14±0.35) points vs. (4.97±0.62) points], and the differences were statistically significant (t=10.574 and 27.824; both P<0.05). The scores of each item in the Comfort Scale for Delivery (GCQ) of the observation group were all higher than those of the control group 2 days after delivery, and the duration of the labor process of the observation group was shorter than that of the control group (all P<0.05). The total incidence rate of adverse delivery outcomes in the observation group was lower than that in the control group [4.08% (2/49) vs. 16.33% (8/49)], and the difference was statistically significant (χ²=4.009, P<0.05). The scores of satisfaction in the observation group were all higher than those in the control group in each aspect (all P<0.05). Conclusion　During the childbirth process of a pregnant woman, using a birthing ball for perineal massage combined with continuous doula accompaniment can alleviate the pain during childbirth, enhance the effect of labor pain relief, improve the negative psychological state of the pregnant woman, increase her sense of security and comfort, facilitate the smooth progress of childbirth, reduce the occurrence of adverse childbirth outcomes, and achieve higher satisfaction among pregnant women.

Objective　To explore the effects of dual-dimensional psychological-behavioral interest-inducing nursing on the blood glucose levels and dietary compliance of preschool children with type 1 diabetes. Methods　A prospective study was adopted. A total of 104 preschool children with type 1 diabetes who were admitted to Henan Children's Hospital from November 2022 to November 2024 were selected. They were randomly divided into a conventional group and a research group, with 52 cases in each group. The research group had 30 males and 22 females, with an age of (4.79±1.12) years and a disease duration of (8.04±2.39) months; They received dual-dimensional fun-inducing psychological and behavioral nursing. The control group had 28 males and 24 females, with an age of (4.72±1.05) years and a disease duration of (7.89±1.78) months; They received routine care. The blood glucose levels and dietary compliance before and after the intervention were compared between the two groups. The Self-Rating Anxiety Scale (SAS) and the Self-Rating Depression Scale (SDS) were used to assess the psychological state of the main caregivers. The burden level of the main caregivers was evaluated using the Chinese version of the Caregiver Burden Inventory (CBI). Statistical methods employed t-test and χ² test. Results　After the intervention, the fasting blood glucose (FBG), glycosylated hemoglobin (HbA1c), and 2-hour postprandial blood glucose (2 hPG) in the study group were all lower than those in the control group [(5.04±0.87) mmol/L vs. (6.41±0.66) mmol/L, (6.29±0.89)% vs. (7.20±0.75)%, and (6.31±1.22) mmol/L vs. (7.43±1.07) mmol/L], and the differences were statistically significant (t=9.047, 5.638, and 4.977; all P<0.05). The dietary compliance scores of the research group were all higher than those of the control group (all P<0.05). The SAS and SDS scores of the research group were both lower than those of the control group [(41.65±5.19) points vs. (45.93±3.65) points and (40.02±4.31) points vs. (44.61±6.10) points], and the differences were statistically significant (t=4.864 and 4.432; both P<0.05). The CBI score of the research group was lower than that of the control group [(40.51±5.13) points vs. (46.78±7.06) points], and the difference was statistically significant (t=5.181, P<0.05). Conclusion　The dual-dimensional psychological-behavioral interest-inducing nursing method can not only effectively improve the blood glucose levels of children with type 1 diabetes and enhance their dietary compliance, but also alleviate the negative emotions of the main caregivers and reduce the burden of care.

Objective　To explore the impact of an individualized nutrition management plan based on the WeChat platform on the nutritional status, dietary compliance with renal diet, and related anthropometric indicators of peritoneal dialysis (PD) patients. Methods　A prospective study was adopted. The patients who were regularly followed up at the PD nursing specialty clinic of the First Affiliated Hospital of Fujian Medical University from August 2022 to November 2023 were selected and divided into two groups using the random number table method. The control group consisted of 29 males and 13 females, with an age of (50.81±12.22) years. They received routine nutritional management. The intervention group consisted of 24 males and 19 females, with an age of (47.09±12.88) years. They received individualized nutritional management based on the WeChat platform. Both groups were intervened for 3 months. The nutritional status, the score of the Renal Diet Adherence Questionnaire (RABQ), and the related human measurement indicators of nutrition were compared between the two groups. Statistical methods employed were t-test, Mann-Whitney U test, and χ² test. Results　After the intervention, the incidence rate of malnutrition in the intervention group was lower than that in the control group [9.30% (4/43) vs. 28.57% (12/42)], and the RABQ score was higher [89.0 (88.0, 90.0) points vs. 84.0 (77.8, 89.0) points], and the differences were statistically significant (χ²=5.163 and Z=-4.087; both P<0.05). The anthropometric indicators of the intervention group, such as triceps skinfold thickness (TSF) and upper arm circumference (MAC), were both greater than those of the control group [16.0 (13.3, 18.5) mm vs. 11.8 (9.0, 17.0) mm and 27.0 (25.0, 30.0) cm vs. 24.5 (22.0, 28.0) cm], and the differences were statistically significant (Z=-2.089 and -2.552; both P<0.05). Conclusion　Implementing individualized nutritional management for PD patients through the WeChat platform can help improve their nutritional status and enhance the compliance of their dietary behaviors regarding kidney diseases.

Objective　To analyze the factors influencing core competence in oncology nursing among nursing staff in Shaanxi Province using logistic regression and decision tree interaction detection, and to provide some evidences for optimizing training and intervention strategies. Methods　A total of 1 529 nurses from 62 hospitals in Shaanxi Province from August to September 2022 were selected as the survey subjects, including 26 males and 1 503 females. There were 397 nurses, 580 senior nurses, 485 nurses-in-charge, and 67 chief nurses. A self-designed general information and core competency questionnaire was used for the cross-sectional survey. χ² test, logistic regression analysis, and decision tree interaction detection were used to analyze the differences between the results of the two models. Results　A total of 1 650 questionnaires were distributed, and 1 529 valid ones were ultimately collected, with an effective response rate of 92.67%. The total core competency score was 186.24±59.76, indicating a moderate proficiency. The logistic regression model showed that obtaining municipal-level oncology certification (OR=0.43, 95%CI 0.26-0.73), participating in oncology training (OR=2.19, 95%CI 1.31-3.60), and working in oncology departments (OR=0.51, 95%CI 0.37-0.71) were the predictive factors of core competence in oncology nursing. The decision tree analysis prioritized work satisfaction as the primary factor, followed by certification, training, and oncology department affiliation. The area under the ROC (AUC) of the logistic regression model was 0.745, and the AUC of the decision tree model was 0.721. There is no statistical difference in the prediction efficiency between the two prediction models (Z=1.943; P>0.05). Conclusions　Core competence in oncology nursing of nursing staff in Shaanxi Province is at a moderate level. Work satisfaction, certification, training, and oncology department affiliation are critical influencing factors. Integrating logistic regression's quantitative risk assessment with decision tree's dynamic pathway analysis enhances prediction accuracy. Managers should adopt dual-model strategies to establish baseline standards and design tiered interventions for high-risk subgroups.

Objective　To understand the sleep status of primary and secondary school students in the Bincheng District of Binzhou City and analyze its influencing factors, and oprovide countermeasures for improving the sleep quality of primary and secondary school students. Methods　This survey was conducted from May to June 2023. A stratified sampling method was adopted to select 534 primary and secondary school students in the Bincheng District of Binzhou City as the survey objects. A self-designed electronic questionnaire was used to investigate the sleep status of primary and secondary school students. Results　14.79% of primary school students sleeped less than 8 hours, 40.96 percent of middle school students between the than 7 hours, and 52.26 percent of high school students between the less than 6 hours. The sleeping time of primary school students mainly concentrated in 21:00－22:00 (47.47%) and 22:00－23:00 (38.52%). The sleeping time of junior and senior students was mainly 22:00－23:00 (35.74%) and 23:00－24:00 (19.13%), the waking time of primary school students mainly 06:30－07:00 (61.48%), and that of junior and senior high school students 05:30－06:00 (54.15%). There were significant differences in the time of falling asleep and getting up in the morning between the students of different school ages (P<0.05). The most prominent sleep-related psychological problems of primary and secondary school students were morning difficulty (35.77%); It was followed by daytime sleepiness (14.79%), poor attention (14.05%), poor memory (11.61%), anxiety (10.67%), and depression (8.05%). Multivariate logistic regression analysis showed that late bedtime (OR=4.205, 95%CI: 1.608～10.997) and distance from home to school (OR=1.946, 95%CI: 1.108-3.419) affected the sleep time of primary school students (P<0.05). Late sleep time (OR=7.106, 95%CI: 3.718～13.578) affected the sleep time of middle and high school students (P<0.05). Conclusions　The majority of primary and middle school students in Binzhou City have insufficient sleep time, some of them have sleep-related psychological problems and late sleep time is a risk factor affecting sleep time. It is suggested that relevant departments should pay attention to and strengthen children's sleep health education, home-school co-education, and effectively improve the sleep quality of primary and secondary school students.

Objective　To explore the application effect of the objective structured clinical examination (OSCE) teaching method based on real clinical cases in the clinical teaching of fall care for elderly patients. Methods　A prospective experimental research design was adopted. A total of 60 nursing students who were on internship at the Second Hospital of Traditional Chinese Medicine of Guangdong Province from July 2024 to May 2025 were selected as research subjects through cluster random sampling. They were divided into a control group and an experimental group by the random number table method, with 30 cases in each group. The control group comprised 25 females and 5 males, aged 20.87±0.49 years, including 26 with associate degrees and 4 with bachelor's degrees; the experimental group consisted of 25 females and 5 males, aged 21.13±0.35 years, including 23 with associate degrees and 7 with bachelor's degrees. The control group received traditional teaching methods, while the experimental group underwent OSCE-style teaching based on real fall cases in addition to traditional instruction. Theoretical assessment scores, practical skill evaluation results, and teaching satisfaction were compared between the two groups. Data analysis was performed using t-tests and chi-square tests. Results　The total scores of theoretical and operational skills assessment and teaching satisfaction in the experimental group were higher than those in the control group [(94.63±2.08) points vs. (86.7±3.15) points, (91.47±2.8) points vs. (79.9 ±3.1) points, and (22.23±1.14) points vs. (16.83±1.53) points], and the differences were statistically significant (t=11.511, 15.164, and 15.505; all P<0.001). Conclusion　Integrating OSCE teaching with real clinical cases significantly improves nursing students,learning outcomes and satisfaction in the education of fall-related adverse events.