关键词:

介入治疗, 前循环, 脑梗死, 构音障碍, 社区研究

Abstract:

Objective　To explore the effect of interventional therapy for patients with dysarthria after acute anterior circulatory cerebral infarction. Methods　From January 2020 to December 2024, 174 patients with dysarthria after anterior circulatiory acute cerebral infarction from Guangzhou communities treated at the First Affiliated Hospital of Guangzhou Medical University were selected for the prospective study. There were 119 males and 55 females. They were (66.71±11.54) years old. The patients were divided into an interventional group (85 cases) and a conservative group (89 cases). In the interventional group, stent implantation was performed in the narrow carotid arteies or middle cerebral arteries on the basis of conventional conservative treatment. The conservative group only received conventional conservative treatment. The differences of the scores of the Frenchay, modified Rankin Scale (mRS) and National Institutes of Health Stroke Scale (NIHSS) (△Frenchay, △mRS, and △NIHSS) were evaluated at admission and 10 days after the treatment. The scores of Frenchay, NIHSS, and mRS and frequency of mRS≤2 10 and 90 d after the treatment were evaluated. For data analysis, t test, χ² test, or Mann-Whitney U test were used for the inter-group comparisons, and Wilcoxon signed rank test was used for the intra-group comparisons. The correlation was analyzed using Spearman correlation analysis. Results　Ten days after the treatment, the scores of Frenchay, NIHSS, and mRS were all significantly lower than those before the treatment in both groups (all P<0.01); ninety days after the treatment, the above three indicators were further improved compared with those ten days after the treatment (all P<0.01). The △Frenchay, △mRS, and △NIHSS in the interventional group were higher than those in the conservative group (all P<0.05). Ten and ninety days after the treatment, the scores of Frenchay, mRS, and NIHSS in the interventional group were significantly lower than those in the conservative group (all P<0.05), while the frequencies of mRS≤2 were significantly higher (P<0.01). Ten days after the treatment, the △Frenchay was positively correlated with △NIHSS and △mRS in both groups (r=0.446, 0.409, 0.486, and 0.269; all P<0.05). Conclusions　Interventional therapy for patients with dysarthria after acute anterior circulatory cerebral infarction can improve the therapeutic effect. The improvement of dysarthria parallels the recovery of neurological function.

Key words:

Interventional therapy, Anterior circulation, Cerebral infarction, Dysarthria, Community research