关键词:

重叠综合征, 脑梗死, 系统性红斑狼疮, 狼疮性肾炎

Abstract:

This article reports one patient with newly diagnosed overlap syndrome whose cardiolipin antibodies and lupus anticoagulants were negative. During the patient's oral rivaroxaban anticoagulant treatment, he had cerebral infarction three times (in different parts of the same cerebral blood vessel) within one month. The patient is currently receiving relevant treatment in another hospital. This tells us that when clinicians encounter patients with clinical symptoms that are highly suspected of antiphospholipid antibody syndrome, but their antiphospholipid antibodies and lupus anticoagulants are negative, they should still actively search for non-standard antibodies and screen for hereditary thrombophilia.

Key words:

Overlap syndrome, Cerebral  , infarction, Systemic lupus erythematosus, Lupus nephritis