国际医药卫生导报 ›› 2025, Vol. 31 ›› Issue (2): 221-223.DOI: 10.3760/cma.j.cn441417-20240719-02009

• 医学新进展 • 上一篇    下一篇

探讨不良饮食习惯与腐胺及胃炎癌转化的关系

孙虓  刘成霞  王娜  郝佳慧  储琳琳  于瑞杰   

  1. 滨州医学院附属医院消化内科,滨州  256600

  • 收稿日期:2024-07-19 出版日期:2025-01-15 发布日期:2025-01-15
  • 通讯作者: 刘成霞,Email:phdlcx@163.com
  • 基金资助:

    山东省省级临床重点学科建设(SLCZDZK-13);滨州市科技发展计划(2015ZC0319)

Relationship of adverse dietary habits with putrescine and gastritis carcinomatous transformation

Sun Xiao, Liu Chengxia, Wang Na, Hao Jiahui, Chu Linlin, Yu Ruijie   

  1. Department of Gastroenterology, Binzhou Medical University Hospital, Binzhou 256600, China

  • Received:2024-07-19 Online:2025-01-15 Published:2025-01-15
  • Contact: Liu Chengxia, Email: phdlcx@163.com
  • Supported by:

    Shandong Provincial Key Clinical Discipline Construction (SLCZDZK-13); Binzhou Science and Technology Development Plan (2015ZC0319)

摘要:

肠型胃癌是最常见的胃癌病理类型,其形成过程称为胃炎癌转化。目前,越来越多的研究证实胃液腐胺参与并促进胃炎癌转化。饮食是胃液中外源性腐胺的主要来源之一。高盐饮食和长期大量摄入腌制食物、红肉等可以影响胃液腐胺浓度,破坏多胺代谢稳定。本文综述了不良饮食习惯、腐胺及胃炎癌转化的关系,以探讨不良饮食习惯通过影响胃液腐胺水平来促进胃炎癌转化的演变,以期通过一定的干预措施降低胃癌的发病率。

关键词:

不良饮食习惯, 腐胺, 胃炎癌转化, 进展

Abstract:

Intestinal type gastric cancer is the most common pathological type of gastric cancer, and its formation process is called gastritis carcinomatous transformation. At present, more and more studies have confirmed that putrescine in gastric juice is involved in and promotes the transformation of gastritis into cancer. Diet is one of the main sources of exogenous putrescine in gastric juice. Long-term and large intake of high-salt food, pickled food, and red meat can affect the concentration of putrescine in gastric juice and destroy the stability of polyamine metabolism. This article reviews the relationship between adverse dietary habits, putrescine, and gastric cancer transformation, so as to explore that adverse dietary habits promote the evolution of gastritis cancer transformation affecting the concentration of putrescine in gastric juice and to reduce the incidence rate of gastric cancer through certain intervention measures.

Key words:

Adverse dietary habits, Putrescine, Gastritis carcinomatous transformation, Progress