萝卜硫素在消化系统肿瘤治疗中的机制研究进展

doi:10.3760/cma.j.issn.1007-1245.2023.19.016

摘要/Abstract

摘要：

消化系统肿瘤病死率在全球肿瘤中位于前列，包括手术、化疗和放疗在内的传统治疗方法存在效果差和耐药的缺点。近年来，萝卜硫素作为一种天然抗肿瘤化合物在消化系统肿瘤中被广泛研究，可通过促进癌细胞死亡、阻碍癌细胞增殖、抑制癌细胞侵袭和转移、抗血管生成、加强免疫治疗及减弱耐药性等机制来治疗癌症。本文综述了国内外研究机构关于萝卜硫素治疗消化系统肿瘤机制的研究进展，为消化系统肿瘤的治疗提供新思路。

关键词:

萝卜硫素, 消化系统肿瘤, 治疗机制, 进展

Abstract:

The mortality rate of digestive system cancer is among the highest in the world. Traditional treatment methods, including surgery, chemotherapy, and radiotherapy, have the disadvantages of poor efficacy and drug resistance. In recent years, sulforaphane, as a natural anti-tumor compound, has been widely studied in digestive system tumors. It can treat cancer by promoting cancer cell death, hindering cancer cell proliferation, inhibiting cancer cell invasion and metastasis, anti-angiogenesis, strengthening immunotherapy, and weakening drug resistance. This article reviews the research progress of sulforaphane in the treatment of digestive system tumors in domestic and foreign research institutions, so as to provide new ideas for the treatment of digestive system tumors.

Key words:

Sulforaphane, Digestive system tumors, Mechanisms of treatment, Progress

安嘉琪谢庆芝.

萝卜硫素在消化系统肿瘤治疗中的机制研究进展 [J]. 国际医药卫生导报, 2023, 29(19): 2732-2736.

An Jiaqi, Xie Qingzhi.

Research progress on the mechanism of sulforaphane in the treatment of digestive system tumors [J]. International Medicine and Health Guidance News, 2023, 29(19): 2732-2736.

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