国际医药卫生导报 ›› 2024, Vol. 30 ›› Issue (11): 1776-1780.DOI: 10.3760/cma.j.issn.1007-1245.2024.11.004

• 医学新进展 • 上一篇    下一篇

超声评估女性不孕患者子宫内膜容受性的研究进展

胡玉娟1  洪晓芳1  张舒悦1  钟健星2  宋础均2  崔旭2  梁伟翔1  刘韬1   

  1. 1广东省产科重大疾病重点实验室 广东省妇产疾病临床医学研究中心 广州医科大学附属第三医院超声医学科,广州 510150;2广州医科大学第三临床学院,广州 510180

  • 收稿日期:2024-01-18 出版日期:2024-06-01 发布日期:2024-06-25
  • 通讯作者: 梁伟翔,Email:weixiangl@163.com
  • 基金资助:

    广东省医学科研基金(粤卫科教函[2024]2号-15);广东省教育厅高等教育教学改革建设项目(粤教高函[2021]29号-454);广州市卫生健康科技一般引导项目(穗卫科教[2022]3号-91);广州医科大学2023年度本科教学质量与教学改革工程建设项目(广医发[2023]166号-174);广州医科大学第二临床学院2023年高水平大学“一流本科专业建设经费”资助项目—学生创新能力提升计划项目(广医大二院发[2023]5号-40)

Research progress on ultrasound in evaluation of endometrial receptivity in female infertility patients

Hu Yujuan1, Hong Xiaofang1, Zhang Shuyue1, Zhong Jianxing2, Song Chujun2, Cui Xu2, Liang Weixiang1, Liu Tao1   

  1. 1 Department of Ultrasound Medicine, Guangdong Provincial Key Laboratory of Major Obstetric Diseases, Guangdong Provincial Clinical Research Center for Obstetrics and Gynecology, Third Hospital, Guangzhou Medical University, Guangzhou 510150, China; 2 Third Clinical College, Guangzhou Medical University, Guangzhou 510180, China

  • Received:2024-01-18 Online:2024-06-01 Published:2024-06-25
  • Contact: Liang Weixiang, Email:weixiangl@163.com
  • Supported by:

    Guangdong Medical Research Fund (No.2024215); Project for College and University Teaching Reform and Construction of Guangdong Education Department (No.202129454); General Guiding Project of Health Science and Technology in Guangzhou (No.2022391); Project of Reform Program for Undergraduate Teaching and Teaching Quality of Guangzhou Medical University in 2023 (No.2023166174); Project of Plan for Improving Student Innovation of Program Supported by First Class Subject Construction Fund of High Level University at Second Clinical College, Guangzhou Medical University in 2023 (No.2023540)

摘要:

近年来,越来越多的女性因生育或再生育问题寻求辅助生殖技术助孕,不孕不育症已成为影响人类健康的重大问题。良好的子宫内膜容受性(endometrial receptivity,ER)是成功妊娠的决定因素之一,准确、高效地评估ER成为研究热点。通常认为子宫内膜组织活检是评估ER的金标准,但因其有创性、评价结果滞后难以反映即时ER而受限于临床应用。超声是一种无创的检查手段,可以连续、实时监测,被广泛应用于女性不孕症的诊疗中,已成为不孕症的首选检查方法。本综述主要针对于ER的评估,详细叙述超声下子宫内膜形态、子宫内膜血流、子宫内膜蠕动波、子宫内膜造影、子宫内膜弹性等的研究进展。

关键词:

不孕症, 子宫内膜容受性, 超声, 进展

Abstract:

In recent years, more and more women have sought assisted reproductive technology to help them conceive due to fertility or reproduction problems. Infertility has become a major problem affecting human health. Good endometrial receptivity (ER) is a key factor for successful pregnancy, and accurate and efficient assessment of endometrial receptivity has become a research hotspot. Endometrial pathology biopsy techniques are generally considered the gold standard for the evaluation of ER. However, due to its invasiveness and lag in evaluation, it is difficult to reflect the immediate endometrial receptivity, so its clinical application is limited. As a non-invasive examination method, ultrasound can continuously monitor in real-time during the cycle, and has been widely used in the diagnosis and treatment of female infertility, and has become the preferred examination method for infertility. This review focuses on ER, and describes the research progress of ultrasound endometrial morphology, endometrial blood flow, endometrial peristalsis wave, endometriography, and endometrial elastography in detail.

Key words:

Infertility, Endometrial receptivity, Ultrasound, Progress