Pathogenesis of diabetic foot complicated with osteoporosis

doi:10.3760/cma.j.cn441417-20241114-10009

Abstract

Abstract:

Diabetes is a systemic disease. With the progression of the disease, it will lead to a variety of serious complications, and bone metabolism will also be affected. The onset of diabetic bone changes is insidious, so it is often ignored. Patients with diabetes have higher risk of osteoporosis than ordinary people. Patients with diabetic foot are more likely to suffer from osteoporosis than patients with simple diabetes due to poor blood glucose control, vascular neuropathy, chronic inflammation, and other reasons, resulting in pathological fracture, which increases the difficulty of treatment and treatment cost, and causes heavy family and social burden. This article aims to explore the pathogenesis of osteoporosis in diabetic foot patients and to provide evidences for the early prevention and treatment of osteoporosis in diabetic foot patients.

Key words: Diabetic foot, , Type 2 diabetes, , Osteoporosis, , Bone metabolism, , Progress

摘要：

糖尿病是一种全身性疾病。随着疾病进展，糖尿病会引起多种严重并发症，骨代谢也会受到影响。糖尿病性骨骼改变发病较为隐匿，常被忽视。糖尿病患者患骨质疏松（osteoporosis，OP）的风险较普通人更高。糖尿病足（diabetic foot，DF）患者因为血糖控制不佳、血管神经病变、慢性炎症等，较单纯糖尿病患者更容易患OP，导致病理性骨折，从而增加治疗难度，增加治疗费用，造成沉重的家庭及社会负担。本文探讨DF患者并发OP的发病机制，为指导DF患者早期预防及治疗OP提供依据。

关键词: 糖尿病足, , , 2型糖尿病, , , 骨质疏松, , , 骨代谢, , , 进展

Feng Deping, Zhang Kaige, Li Ruonan.

Pathogenesis of diabetic foot complicated with osteoporosis [J]. International Medicine and Health Guidance News, 2025, 31(10): 1628-1631.

冯德萍张凯歌李若楠. 糖尿病足合并骨质疏松的发病机制探讨 [J]. 国际医药卫生导报, 2025, 31(10): 1628-1631.

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