Analysis of fundus fluorescein angiography in neonates

doi:10.3760/cma.j.issn.1007-1245.2022.20.025

Abstract

Abstract: Objective　To observe and analyze the results of fundus fluorescein angiography (FFA) in 12 neonates, and to clarify the application value of FFA in the diagnosis and treatment of neonatal retinopathy. Methods　From February 2021 to March 2022, 12 neonates with retinopathy diagnosed by neonatal fundus screening in Linyi Maternal and Child Health Care Hospital were selected, including 8 males and 4 females, with gestational age of 27-40 weeks. FFA was performed by Retcam Ⅲ digital wide-area fundus imaging system, and the results were observed and analyzed. Results　The FFA results of 4 neonates showed that the retinal blood vessels were well filled, which was considered as retinopathy of prematurity. The FFA results of 2 neonates showed familial exudative vitreoretinopathy. The FFA results of 2 neonates showed active stage of retinopathy of prematurity, and they were treated with vitreous anti-VEGF (vascular endothelial growth factor). The FFA results of 4 neonates showed degenerative stage of retinopathy of prematurity. Conclusions　FFA can be used for early diagnosis of neonatal retinopathy, displaying the stage of disease more clearly, and has important guiding significance for the further treatment of neonatal retinopathy.

Key words: Fundus fluorescein angiography, Neonatal retinopathy, Diagnosis

摘要： 目的　观察分析12例新生儿荧光素钠眼底血管造影（FFA）结果，明确FFA在新生儿视网膜病变诊疗中的应用价值。方法　选取2021年2月至2022年3月在临沂市妇幼保健院进行新生儿眼底筛查发现视网膜病变的12例新生儿，其中男8例、女4例，出生胎龄27～40周。采用Retcam Ⅲ数字化广域眼底成像系统进行FFA检查，观察并分析造影结果。结果　4例患儿FFA示视网膜血管充盈良好，考虑类早产儿视网膜病变；2例患儿FFA结果提示家族性渗出性玻璃体视网膜病变；2例患儿FFA结果提示早产儿视网膜病变活动期，予双眼玻璃体抗血管内皮生长因子治疗；4例患儿FFA结果提示早产儿视网膜病变退行期。结论　FFA检查可早期明确新生儿视网膜病变的诊断，更清晰显示病变分期，对新生儿视网膜病变进一步治疗具有重要指导意义。

关键词: 荧光素钠眼底血管造影, 新生儿视网膜病变, 诊断

Xia Jing, Liu Baohai. Analysis of fundus fluorescein angiography in neonates[J]. International Medicine and Health Guidance News, 2022, 28(20): 2928-2931.

夏静刘宝海. 新生儿荧光素钠眼底血管造影结果分析[J]. 国际医药卫生导报, 2022, 28(20): 2928-2931.

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