Abstract:

Objective　To investigate the effect of mindfulness-based stress reduction therapy combined with graded nutritional status nursing for patients with colon cancer. Methods　A prospective study was conducted on 100 patients with colon cancer treated at The Second Affiliated Hospital of Nanchang University from June 2022 to June 2024. They were divided into a control group and an observation group by the the random number table method. In the control group, there were 31 males and 19 females; they were 39-75 (46.75±4.65) years old; there were 14 cases of stage Ⅰ, 26 cases of stage Ⅱ, and 10 cases of stage Ⅲ. In the observation group, there were 32 males and 18 females; they were 40-75 (46.65±4.63) years old; there were 13 cases of stage Ⅰ, 28 cases of stage Ⅱ, and 9 cases of stage Ⅲ. The control group took conventional nursing; in addition, the observation group took mindfulness-based stress reduction therapy combined with graded nutritional status nursing. The psychological status, nutritional indicators, and scores of Colorectal Cancer Quality of Life Dedicated Scale (QLQ-CR38) were compared between the two groups. χ², rank sum, independent-sample t, and paired t tests were used for the statistical analysis. Results　After 8 weeks' intervention, the scores of the Depression Self-assessment Scale (SDS), Anxiety Self-assessment Scale (SAS) , and Patient Subjective Global Assessment Scale (PG-SGA) in the observation group were lower than those in the control group (43.55±4.36 vs. 47.18±4.70, 42.15±4.22 vs. 46.25±4.63, and 5.11±0.52 vs. 7.25±0.73), with statistical differences (t=4.004, 4.628, and 16.883; all P<0.05). After 8 weeks' intervention, the levels of albumin (ALB) and prealbumin (PA) in the observation group were higher than those in the control group [(42.35±4.25) g/L vs. (39.58±3.55) g/L and (0.32±0.03) g/L vs. (0.26±0.02) g/L], (t=3.537 and 11.767; both P<0.05). After                8 weeks' intervention, the observation group had lower score in the symptom domain and higher score in the functional domain than the control group (50.15±5.02 vs. 75.36±7.54 and 21.25±2.13 vs. 17.38±1.74), with statistical differences (t=19.680 and 9.950; both P<0.05). Conclusion　Mindfulness-based stress reduction therapy combined with graded nutritional status nursing for patients with colon cancer can relieve their negative emotions, and improve their nutritional status and quality of life after surgery.

Key words: Colon cancer,  , Mindfulness-based stress reduction therapy,  , Nutritional status grading,  , Malnutrition,  , Quality of life

摘要：

目的　探究正念减压疗法联合营养状态分级护理在结肠癌患者术后中的应用。方法　采用前瞻性研究，共纳入南昌大学第二附属医院2022年6月至2024年6月收治的100例结肠癌患者，按照随机数字表法分为两组，各50例。对照组男31例，女19例；年龄39～75（46.75±4.65）岁；临床分期：Ⅰ期14例，Ⅱ期26例，Ⅲ期10例。观察组男32例，女18例；年龄40～75（46.65±4.63）岁；临床分期：Ⅰ期13例，Ⅱ期28例，Ⅲ期9例。对照组行常规护理，观察组在此基础上行正念减压疗法联合营养状态分级护理。对比两组心理状况、营养指标、结直肠癌生活质量专用量表（QLQ-CR38）。采用χ2检验和t检验进行统计学分析。结果　干预8周后，观察组抑郁自评量表（SDS）、焦虑自评量表（SAS）评分、患者主观整体评估量表（PG-SGA）评分均较对照组低［（43.55±4.36）分比（47.18±4.70）分、（42.15±4.22）分比（46.25±4.63）分、（5.11±0.52）分比（7.25±0.73）分］，差异均有统计学意义（t=4.004、4.628、16.883，均P<0.05）。干预8周后，观察组白蛋白（ALB）、前白蛋白（PA）水平均比对照组高［（42.35±4.25）g/L比（39.58±3.55）g/L、（0.32±0.03）g/L比（0.26±0.02）g/L］，差异均有统计学意义（t=3.537、11.767，均P<0.05）。干预8周后，观察组症状领域评分比对照组低，功能领域评分比对照组高［（50.15±5.02）分比（75.36±7.54）分、（21.25±2.13）分比（17.38±1.74）分］，差异均有统计学意义（t=19.680、9.950，均P<0.05）。结论　正念减压疗法联合营养状态分级护理可减轻结肠癌手术患者的负性情绪，改善其营养状况，提高术后生活质量。

关键词:  , 结肠癌,  ,  , 正念减压疗法,  ,  , 营养状态分级,  ,  , 营养不良,  ,  , 生活质量