康复新液联合金黄膏对混合痔患者术后创面愈合及肛门功能的影响

doi:10.3760/cma.j.issn.1007-1245.2024.15.025

国际医药卫生导报 ›› 2024, Vol. 30 ›› Issue (15): 2590-2594.DOI: 10.3760/cma.j.issn.1007-1245.2024.15.025

康复新液联合金黄膏对混合痔患者术后创面愈合及肛门功能的影响

刘智¹ 徐秀兰²

¹九江市濂溪区中医医院普通外科，九江　332099；²九江市第一人民医院妇科，九江 332000

收稿日期:2024-05-28 出版日期:2024-08-01 发布日期:2024-09-02
通讯作者: 刘智，Email：liuzhi44662024@163.com
基金资助:
江西省中医药管理局科技计划（2023B1036）

Effect of Kangfuxin Solution combined with Jinhuang Paste on wound healing and anal function in patients with mixed hemorrhoids after operation

Liu Zhi¹, Xu Xiulan²

¹Department of General Surgery, Lianxi District Hospital of Traditional Chinese Medicine, Jiujiang 332099, China; ²Department of Gynecology, Jiujiang First People's Hospital, Jiujiang 332000, China

Received:2024-05-28 Online:2024-08-01 Published:2024-09-02
Contact: Liu Zhi, Email: liuzhi44662024@163.com
Supported by:
Scientific and Technological Plan of Jiangxi Administration Bureau of Traditional Chinese Medicine (2023B1036)

摘要/Abstract

摘要：

目的　探讨康复新液联合金黄膏对混合痔患者术后创面愈合及肛门功能的影响。方法　选取2023年3月至2024年3月于九江市濂溪区中医医院接受手术治疗的混合痔患者96例进行随机对照试验。采用抽签法将其分为对照组、治疗组，各48例。对照组男26例，女22例，年龄（42.52±4.62）岁，病程（7.57±1.15）年，创面面积（3.11±0.86）cm²。治疗组男27例，女21例，年龄（42.88±4.70）岁，病程（7.63±1.30）年，创面面积（3.30±0.75）cm²。对照组术后予常规治疗，治疗组在常规治疗基础上采用康复新液联合金黄膏治疗，两组均治疗7 d。对比两组术后创面疼痛程度、创面愈合情况、炎症指标及肛门功能。符合正态分布的计量资料采用t检验，计数资料用χ²检验。结果　治疗后，治疗组视觉模拟量表评分低于照组［（2.54±0.85）分比（3.97±0.97）分］，差异有统计学意义（t=7.682，P<0.001）。治疗组创面水肿消失时间、新生肉芽组织与创面相平时间、创面愈合时间均短于对照组［（5.11±1.12）d比（6.78±1.30）d、（11.25±1.85）d比（14.25±1.65）d、（16.35±2.87）d比（20.84±2.98）d］，差异均有统计学意义（t=6.743、8.385、7.519，均P<0.05）。治疗后，治疗组白细胞介素6、C反应蛋白水平低于对照组［（12.01±1.55）ng/L比（16.58±2.14）ng/L、（9.25±1.02）mg/L比（13.52±2.14）mg/L］，肛管静息压、肛管最大收缩压及肛管舒张压高于对照组［（55.85±5.87）mmHg比（50.24±4.97）mmHg（1 mmHg=0.133 kPa）、（122.25±13.65）mmHg比（115.69±12.24）mmHg、（93.52±16.35）mmHg比（86.24±15.42）mmHg］，差异有统计学意义（t=11.982、12.479、5.053、2.479、2.242，均P<0.05）。结论　混合痔患者采用康复新液联合金黄膏治疗可减轻术后创面疼痛，促进创面愈合，降低炎症反应，改善肛门功能。

关键词:

混合痔, 康复新液, 金黄膏, 创面愈合, 肛门功能

Abstract:

Objective　To investigate the effect of Kangfuxin Solution combined with Jinhuang Paste on wound healing and anal function in patients with mixed hemorrhoids after surgery. Methods　Ninety-six patients with mixed hemorrhoids who received surgical treatment at Lianxi District Hospital of Traditional Chinese Medicine from March 2023 to March 2024 were selected for the randomized controlled trial, and were divided into a control group and a treatment group by drawing lots, with 48 cases in each group. There were 26 males and 22 females in the control group; they were (42.52±4.62) years old; their disease course was (7.57±1.15) years; their wound area was (3.11±0.86) cm². There were 27 males and 21 females in the treatment group; they were (42.88±4.70) years old; their disease course was (7.63±1.30) years; their wound area was (3.30±0.75) cm². The control group received conventional treatment after the operation; in addition, the treatment group were treated with Kangfuxin Solution and Jinhuang Paste; both groups were treated for 7 days. The degrees of postoperative wound pain, wound healing, inflammation indicators, and anal function were compared between the two groups. The measurement data of normal distribution were tested by t test. The count data were tested by χ² test. Results　After the treatment, the score of Visual Analogue Scale in the treatment group was lower than that in the control group [(2.54±0.85) vs. (3.97±0.97)], with a statistical difference (t=7.682; P<0.001). The time for disappearance of wound edema, the time of granulation formation and wound flatness, and the time of wound healing in the treatment group were shorter than those in the control group [(5.11±1.12) d vs. (6.78±1.30) d, (11.25±1.85) d vs. (14.25±1.65) d, and (16.35±2.87) d vs. (20.84±2.98) d], with statistical differences (t=6.743, 8.385, and 7.519; all P<0.05). After the treatment, the levels of interleukin 6 and C-reactive protein in the treatment group were lower than those in the control group [(12.01±1.55) ng/L vs. (16.58±2.14) ng/L and (9.25±1.02) mg/L vs. (13.52±2.14) mg/L]; the anal canal resting pressure, maximum anal systolic pressure, and anal diastolic pressure in the treatment group were higher than those in control group [(55.85±5.87) mmHg vs. (50.24±4.97) mmHg (1 mmHg=0.133 kPa), (122.25±13.65) mmHg vs. (115.69±12.24) mmHg, and (93.52±16.35) mmHg vs. (86.24±15.42) mmHg], with statistical differences (t=11.982, 12.479, 5.053, 2.479, and 2.242; all P<0.05). Conclusion　Kangfuxin Solution and Jinhuang Paste for patients with mixed hemorrhoids can alleviate their postoperative wound pain, promote their wound healing, reduce inflammatory response, and improve their anal function.

Key words:

Mixed hemorrhoids, Kangfuxin Solution, Jinhuang Paste, Wound healing, Anal function

刘智徐秀兰.

康复新液联合金黄膏对混合痔患者术后创面愈合及肛门功能的影响 [J]. 国际医药卫生导报, 2024, 30(15): 2590-2594.

Liu Zhi, Xu Xiulan.

Effect of Kangfuxin Solution combined with Jinhuang Paste on wound healing and anal function in patients with mixed hemorrhoids after operation [J]. International Medicine and Health Guidance News, 2024, 30(15): 2590-2594.

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康复新液联合金黄膏对混合痔患者术后创面愈合及肛门功能的影响

Effect of Kangfuxin Solution combined with Jinhuang Paste on wound healing and anal function in patients with mixed hemorrhoids after operation

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