支气管肺泡灌洗液中细胞学对儿童肺部疾病诊治研究进展

doi:10.3760/cma.j.issn.1007-1245.2023.08.004

国际医药卫生导报 ›› 2023, Vol. 29 ›› Issue (8): 1049-1052.DOI: 10.3760/cma.j.issn.1007-1245.2023.08.004

支气管肺泡灌洗液中细胞学对儿童肺部疾病诊治研究进展

马坤¹ 王道斌² 李树军¹

¹新乡医学院第一附属医院儿科，新乡　453100；²柘城县人民医院儿科，商丘　476200

收稿日期:2023-02-28 出版日期:2023-04-15 发布日期:2023-05-01
通讯作者: 李树军，Email：PICU3390@126.com
基金资助:
新乡医学院第一附属医院青年培育基金项目（QN-2020-B08）

Cytology of bronchoalveolar lavage fluid in diagnosis and treatment of pediatric lung diseases

Ma Kun¹, Wang Daobin², Li Shujun¹

¹Department of Pediatrics, The First Affiliated Hospital of Xinxiang Medical University, Xinxiang 453100, China; ²Department of Pediatrics, Zhecheng County People's Hospital, Shangqiu 476200, China

Received:2023-02-28 Online:2023-04-15 Published:2023-05-01
Contact: Li Shujun, Email: PICU3390@126.com
Supported by:
Project of Youth Cultivation Fund of The First Affiliated Hospital of Xinxiang Medical University (QN-2020-B08)

摘要/Abstract

摘要：

肺部疾病对儿童生命健康有很大影响，支气管镜技术在儿童急危重症及难治性疾病中的应用对于儿童肺疾病诊治有了长足进展，支气管肺泡灌洗液（BALF）的分析对提高肺疾病的诊断水平有重要作用；BALF主要成分和疾病关系是目前研究的热点，由于不同疾病的发病机制不同，BALF特点尚未被完全阐明。本文通过对儿童BALF中细胞学与肺疾病的相关研究进行综述，为儿科肺部疾病诊治提供更多依据。

关键词:

支气管肺泡灌洗液, 代谢组学, 蛋白组学, 细胞分类, 肺部疾病, 儿童

Abstract:

Lung diseases have significant impact on children's health. The application of bronchoscopy plays a key role in the diagnosis and treatment of children with pulmonary diseases, especially in severe and refractory pediatric patients. Analysis of bronchoalveolar lavage fluid (BALF) has improved the diagnostic level of lung diseases. Present researchs focus on the main components of BALF and their relationship with diseases. The characteristics of BALF have not been fully elucidated due to different disease mechanisms. This review provides a summary of the recent researches on the cytology of BALF and lung diseases in children, and provides more evidences for the diagnosis and treatment of pediatric lung diseases.

Key words:

Bronchoalveolar lavage fluid, Metabolomics, Proteomics, Cell classification, Lung diseases, Children

马坤王道斌李树军.

支气管肺泡灌洗液中细胞学对儿童肺部疾病诊治研究进展 [J]. 国际医药卫生导报, 2023, 29(8): 1049-1052.

Ma Kun, Wang Daobin, Li Shujun.

Cytology of bronchoalveolar lavage fluid in diagnosis and treatment of pediatric lung diseases [J]. International Medicine and Health Guidance News, 2023, 29(8): 1049-1052.

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支气管肺泡灌洗液中细胞学对儿童肺部疾病诊治研究进展

Cytology of bronchoalveolar lavage fluid in diagnosis and treatment of pediatric lung diseases

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