半导体激光联合30%超分子水杨酸治疗痤疮的疗效和护理体会

doi:10.3760/cma.j.issn.1007-1245.2022.07.031

摘要/Abstract

摘要： 目的　探讨半导体激光联合30%超分子水杨酸治疗痤疮的疗效和护理效果。方法　选取2019年10月至2021年4月在广州市皮肤病防治所就诊的100例痤疮患者，采用随机数字表法分为对照组与研究组，各50例。对照组男19例，女31例，年龄14～41（25.62±8.35）岁，给予半导体激光治疗；研究组男20例，女30例，年龄12～43（26.43±8.12）岁，给予半导体激光联合30%超分子水杨酸治疗。记录患者皮肤纹理特征变化、不良反应，并评估临床疗效及患者满意度；采用t检验、χ²检验进行统计分析。结果　治疗结束后，研究组色斑［（35.41±6.22）%比（40.16±9.37）%］、毛孔［（25.10±6.83）%比（29.65±8.40）%］、红斑［（21.05±8.42）%比（28.18±9.23）%］、紫质［（28.02±9.02）%比（32.60±10.67）%］计数均较对照组减少（t=2.986、2.972、4.035、2.318，均P<0.05）；第2次治疗后研究组临床总有效率44.00%（22/50）均明显高于对照组24.00%（12/50），差异有统计学意义（χ²=4.456，P=0.035），对照组与研究组治疗结束后2个月临床总有效率为54.00%（27/50）、78.00%（39/50），组间比较差异有统计学意义（χ²=6.417，P=0.011）；对照组与研究组痤疮总满意度为88.00%（44/50）、100.00%（50/50），组间比较差异有统计学意义（χ²=8.542，P=0.004）。结论　半导体激光联合30%超分子水杨酸治疗可显著改善痤疮症状，提高临床治疗效果和，同时应配合规范化护理措施，保障临床治疗效果和患者满意度。

关键词: 半导体激光, 30%超分子水杨酸, 痤疮, 疗效, 护理

Abstract:

Objective　To explore the effect of semiconductor laser combined with 30% supramolecular salicylic acid in the treatment of acne and the nursing effect. Methods　A total of 100 patients with acne who were treated at the Guangzhou Institute of Dermatology Prevention and Treatment from October 2019 to April 2021 were selected and divided into a control group and a study group using a random number table method, with 50 cases in each group. The control group had 19 males and 31 females who were 14-41 (25.62 ± 8.35) years old, and were given semiconductor laser treatment. The study group had 20 males and 30 females who were 12 to 43 (26.43±8.12) years old, and were treated with semiconductor laser and 30% supramolecular salicylic acid. The changes in skin texture characteristics and adverse reactions were recorded. The clinical efficacies and patient satisfaction were evaluated. t and χ² tests were used for statistical analysis. Results　After the treatment, the counts of stains, pores, erythema, and purple matter in the study group were lower than those in the control group [(35.41±6.22)% vs. (40.16±9.37)%, (25.10±6.83)% vs. (29.65±8.40)%, (21.05±8.42)% vs. (28.02±9.23)%, (29.31±9.02)% vs. (32.60±10.67)%; t=2.986, 2.972, 4.035, and 2.318; all P<0.05]. After the second treatment, the total clinical effective rate was 44.00% (22/50) in the study group, and was 24.00% (12/50) in the control group, with a statistical difference (χ²=4.456, P=0.035). The total effective rate 2 months after the end of the treatment was 54.00% (27/50) in the control group, and was 78.00% (39/50) in the study group, with a statistical difference (χ²=6.417, P=0.011). The total satisfaction with acne was 88.00% (44/50) in the control group, and was 100.00% (50/50) in the study group, with a statistical difference (χ²=8.542, P=0.004). Conclusions　Semiconductor laser combined with 30% supramolecular salicylic acid can significantly improve the symptoms of acne and the clinical treatment effect. At the same time, standardized nursing measures should be used to ensure the clinical treatment effect and patient satisfaction.

Key words: Semiconductor laser, 30% supramolecular salicylic acid, Acne, Curative effect, Nursing

张文君, 李月明, 何诗琪, 梁淑鸿, 刘映雪, 吴怡玲, 龚业青.

半导体激光联合30%超分子水杨酸治疗痤疮的疗效和护理体会 [J]. 国际医药卫生导报, 2022, 28(7): 1013-1016.

Zhang Wenjun, Li Yueming, He Shiqi, Liang Shuhong, Liu Yingxue, Wu Yiling, Gong Yeqing. Effect of semiconductor laser combined with 30% supramolecular salicylic acid in treatment of acne curative and nursing experience[J]. International Medicine and Health Guidance News, 2022, 28(7): 1013-1016.

参考文献

[1] Li D, Chen Q, Liu Y, et al. The prevalence of acne in Mainland China: a systematic review and meta-analysis[J]. BMJ Open, 2017,7(4):e015354. DOI: 10.1136/bmjopen-2016-015354.

[2] 续凤凤,郎小青,郭书萍.痤疮的治疗进展[J].中国临床研究,2020,33(05):700-702.DOI:10.13429/j.cnki.cjcr.2020. 05.033.

[3] 徐渴鑫,罗赛,郝立君.整形美容外科领域治疗寻常痤疮的新疗法进展[J].中国美容整形外科杂志,2019,30(3):188-190,后插1.DOI:10.3969/j.issn.1673-7040. 2019. 03.020.

[4] 夏栩琼,徐慧,陆雯丽,等.30％超分子水杨酸治疗寻常痤疮的疗效观察[J].中国皮肤性病学杂志,2019,33(5):616-619.DOI:10.13735/j.cjdv.1001-7089.201805076.

[5] 中国痤疮治疗指南专家组.中国痤疮治疗指南(2019修订版)[J].临床皮肤科杂志,2019,48(9):583-588.DOI:10.16761/j.cnki.1000-4963.2019.09.020.

[6] 祝立丽,李杰,李晓东,等.新型超分子水杨酸联合火针治疗面部轻中度寻常型痤疮[J].中国美容整形外科杂志,2018,29(8):469-471,后插2.DOI:10.3969/j.issn.1673-7040. 2018.08.007.

[7] 王子洋,杨希川.女性玫瑰痤疮患者生活质量调查分析[J].临床皮肤科杂志,2019,48(8):473-476.DOI:10.16761/j.cnki.1000-4963.2019.08.005.

[8] 胡南,肖志平,温云鹏,等.超分子水杨酸联合胶原贴敷料治疗轻中度痤疮临床观察[J].临床皮肤科杂志,2018,47(7):464-467.DOI:10.16761/j.cnki.1000-4963.2018.07.021.

[9] 许凌晖,许天星,郭燕妮,等.超分子水杨酸换肤术治疗玫瑰痤疮的疗效观察[J].福建医科大学学报,2019,53(6):433-436.DOI:10.3969/j.issn.1672-4194.2019.06.016.

[10] 姚露,彭红霞,周文瑞,等.超分子水杨酸联合粉刺挤压治疗寻常型痤疮疗效观察[J].皮肤病与性病,2020,42(3):377-379.DOI:10.3969/j.issn.1002-1310.2020.03.032.

[11] 王文娟.剥脱性与非剥脱性点阵激光治疗痤疮瘢痕的效果比较[J].生物医学工程与临床,2020,24(3):298-301.DOI:10.13339/j.cnki.sglc.20200415.004.

[12] 马少吟,龚业青,张文君,等.长脉宽Nd:YAG激光和脉冲染料激光治疗玫瑰痤疮的疗效比较[J].中国激光医学杂志,2019,28(06):314-318,357.DOI:10.13480/j.issn1003- 9430. 2019.0314.

[13] 赵菊花,庄化迪,李娜,等.不同预处理皮损在光动力治疗中重度痤疮的疗效对比研究[J].四川医学,2019,40(12):1200-1204.DOI:10.16252/j.cnki.issn1004-0501- 2019. 12.004.

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