高龄2型糖尿病患者健康状态及糖化血红蛋白调查分析

doi:10.3760/cma.j.cn441417-20250317-15029

国际医药卫生导报 ›› 2025, Vol. 31 ›› Issue (15): 2611-2616.DOI: 10.3760/cma.j.cn441417-20250317-15029

高龄2型糖尿病患者健康状态及糖化血红蛋白调查分析

李晓玉¹ 王小霞² 梁娜红³ 高莹³ 袁莉莉³ 谭云²

¹南方医科大学附属广东省人民医院（广东省医学科学院）广东省老年医学研究所，广州 510080；²南方医科大学附属广东省人民医院（广东省医学科学院）综合三区，广州 510080；³南方医科大学附属广东省人民医院（广东省医学科学院）老年内分泌科，广州 510080

收稿日期:2025-03-17 出版日期:2025-08-01 发布日期:2025-08-26
通讯作者: 谭云，Email：xiaomantan040518@126.com
基金资助:
广东省医学科学技术研究基金（C2022005）

Analysis of health status and glycated hemoglobin levels in elderly patients with type 2 diabetes mellitus

Li Xiaoyu¹, Wang Xiaoxia², Liang Nahong³, Gao Ying³, Yuan Lili³, Tan Yun²

¹Guangdong Provincial Geriatrics Institute, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou 510080, China; ²Comprehensive Zone 3, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou 510080, China; ³Department of Geriatric Endocrinology, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou 510080, China

Received:2025-03-17 Online:2025-08-01 Published:2025-08-26
Contact: Tan Yun, Email: xiaomantan040518@126.com
Supported by:
Guangdong Province Medical Science and Technology Research Fund (C2022005)

摘要/Abstract

摘要：

目的　调查分析高龄2型糖尿病（T2DM）患者健康状态及糖化血红蛋白（HbA1c）分层达标情况，为高龄T2DM患者分层管理和个体化血糖控制提供参考。方法　选取2022年10月至2024年8月在广东省人民医院住院的187例高龄T2DM患者作为研究对象。其中男102例，女85例；年龄（80.94±8.28）岁；T2DM病程（17.25±9.30）年。比较患者临床资料（一般资料、实验室指标及入院前降糖药物使用情况）、健康综合评估［共患病情况、日常生活能力（ADL）等］、HbA1c分层达标情况。结果　高龄T2DM患者健康状态等级良好（Group 1）、中等（Group 2）和差（Group 3）的占比分别为3.74%（7/187）、47.59%（89/187）和48.66%（91/187）。96.26%（180/187）患者合并除糖尿病外的慢性疾病总数≥3种；Group 3 ADL损伤≥2项患者81例，占总体的43.32%（81/187），占Group 3的89.01%（81/91）。未使用低血糖风险较高的药物患者达标率为76.67%（23/30），使用低血糖风险较高的药物患者达标率为13.38%（21/157）。Group 1患者HbA1c达标率为28.57%（2/7）；Group 2患者HbA1c达标率为22.47%（20/89）；Group 3患者HbA1c达标率为24.18%（22/91）；总达标率为23.53%（44/187）。结论　合并除糖尿病外的慢性疾病总数≥3种是高龄T2DM患者健康状态分入Group 2的主要原因，ADL损伤≥2项是高龄T2DM患者健康状态分入Group 3的主要原因。HbA1c达标率低与合并多种慢性疾病、ADL损伤、使用低血糖风险较高的药物等有关。

关键词:

font-family:Calibri, font-size:10.5pt, "> font-size:9pt, "> , 2font-size:9pt, ">型糖尿病；font-size:9pt, ">高龄；font-size:9pt, ">健康状态；font-size:9pt, ">糖化血红蛋白；font-size:9pt, ">达标率

Abstract:

Objective　The study aimed to analyze the health status and the achievement of glycated hemoglobin (HbA1c) stratification attainment in elderly patients with type 2 diabetes mellitus (T2DM), providing a reference for the stratified management and individualized blood glucose control of elderly T2DM patients. Methods　A total of 187 elderly patients with T2DM who were hospitalized at Guangdong Provincial People's Hospital from October 2022 to August 2024 were selected as the study subjects. Among them, there were 102 males and 85 females; the age was (80.94±8.28) years; the duration of T2DM was (17.25±9.30) years. The clinical data (general information, laboratory indicators, and the use of hypoglycemic drugs before admission), the comprehensive health assessment [comorbid conditions, activity of daily living (ADL), etc.], and the HbA1c stratification attainment were compared in the patients. Results　The proportions of elderly patients with T2DM with good (Group 1), moderate (Group 2), and poor (Group 3) health status were 3.74% (7/187), 47.59% (89/187), and 48.66% (91/187), respectively. 96.26% (180/187) of the patients had a total of 3 or more chronic diseases other than diabetes; 81 patients in Group 3 had ≥2 ADL impairments, accounting for 43.32% (81/187) of the total and 89.01% (81/91) of Group 3. The attainment rate of the patients who did not use the drugs with a higher risk of hypoglycemia was 76.67% (23/30), while the attainment rate of the patients who used the drugs with a higher risk of hypoglycemia was 13.38% (21/157). The HbA1c attainment rate for Group 1 patients was 28.57% (2/7); for Group 2 patients, it was 22.47% (20/89); for Group 3 patients, it was 24.18% (22/91); and the overall attainment rate was 23.53% (44/187). Conclusion　The total number of chronic diseases other than diabetes exceeding 3 is the main reason for the elderly T2DM patients to be classified into Group 2 in terms of their health status. The impairment of ADL ≥ 2 items is the main reason for the elderly T2DM patients to be classified into Group 3. The low rate of achieving HbA1c target is related to the coexistence of multiple chronic diseases, ADL impairment, and the use of drugs with a higher risk of hypoglycemia.

Key words:

font-family:Calibri, font-size:10.5pt, "> font-size:9pt, ">Type 2 diabetes mellitus；Elderly；Health status；Glycosylated hemoglobin；Attainment rate

李晓玉王小霞梁娜红高莹袁莉莉谭云.

高龄2型糖尿病患者健康状态及糖化血红蛋白调查分析 [J]. 国际医药卫生导报, 2025, 31(15): 2611-2616.

Li Xiaoyu, Wang Xiaoxia, Liang Nahong, Gao Ying, Yuan Lili, Tan Yun.

Analysis of health status and glycated hemoglobin levels in elderly patients with type 2 diabetes mellitus [J]. International Medicine and Health Guidance News, 2025, 31(15): 2611-2616.

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高龄2型糖尿病患者健康状态及糖化血红蛋白调查分析

Analysis of health status and glycated hemoglobin levels in elderly patients with type 2 diabetes mellitus

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