国际医药卫生导报 ›› 2025, Vol. 31 ›› Issue (15): 2602-2604.DOI: 10.3760/cma.j.cn441417-20250314-15027

• 病例报告 • 上一篇    下一篇

纹带棒状杆菌引起感染性心内膜炎1例并文献分析

李丹1  毕艳妮1  薛明2   

  1. 1山东大学附属威海市立医院检验医学中心,威海 2642002山东大学附属威海市立医院介入科,威海 264200

  • 收稿日期:2025-03-14 出版日期:2025-08-01 发布日期:2025-08-26
  • 通讯作者: 薛明,Email:kech008@163.com
  • 基金资助:

    山东省自然科学基金面上项目(ZR2021MH281

Corynebacterium striatum caused infective endocarditis: a case report

Li Dan1, Bi Yanni1, Xue Ming2   

  1. Department of Central Laboratory, Shandong University Affiliated Weihai Municipal Hospital, Weihai 264200, China1; Department of Interventional Radiology, Shandong University Affiliated Weihai Municipal Hospital, Weihai 264200, China

  • Received:2025-03-14 Online:2025-08-01 Published:2025-08-26
  • Contact: Xue Ming, Email:kech008@163.com
  • Supported by:

    Natural Science Foundation of Shandong Province (ZR2021MH281)

摘要:

本文报道1例纹带棒状杆菌引起的感染性心内膜炎病例并进行相关文献复习。患者52岁,男性,诊断为感染性心内膜炎,多套外周血培养均分离出纹带棒状杆菌。经过详细的临床和实验室评估,最终确诊为纹带棒状杆菌引起感染性心内膜炎。患者接受美罗培南联合万古霉素抗感染治疗,取得了较好的疗效。本文着重强调,纹带棒状杆菌作为条件致病菌,在免疫力低下人群(长期使用抗菌药物、长期血液透析、器官移植、置管等介入性操作、糖尿病、恶性肿瘤)中感染率越来越高,应该引起临床的足够重视。

关键词:

font-family:Calibri, font-size:10.5pt, "> font-size:9pt, ">纹带棒状杆菌;font-size:9pt, ">感染性心内膜炎;font-size:9pt, ">血流感染

Abstract:

This article reports a case of infective endocarditis caused by Corynebacterium striatum and reviews relevant literature. The patient was a 52-year-old male diagnosed with infective endocarditis, from whom Corynebacterium striatum was isolated multiple times from peripheral blood cultures. Following a detailed clinical and laboratory evaluation, a definitive diagnosis of infective endocarditis due to Corynebacterium striatum was made. During treatment, the patient received a combined antibiotic regimen of meropenem and vancomycin, resulting in a favorable outcome. This article emphasizes that Corynebacterium striatum, as an opportunistic pathogen, is increasingly associated with infections in immunocompromised individuals (those with prolonged use of antibiotics, long-term hemodialysis, organ transplantation, interventional procedures such as catheterization, diabetes, and malignancies), and this should alert clinicians to its rising incidence.

Key words:

font-size:9pt, ">Corynebacterium striatumfont-size:9pt, ">;Infective endocarditis;Bloodstream infectionfont-size:9pt, ">