Abstract: Objective　To explore the mediating effect of resilience on medical treatment adherence and quality of life in maintenance hemodialysis (MHD) patients. Methods　A cross-sectional study was used to select 104 patients with chronic kidney disease undergoing MHD in Guangdong Provincial Hospital of Traditional Chinese Medicine from March to May 2021. The Treatment Compliance Scale, Kidney Disease Quality of Life Short Form, and Chinese version of Psychological Resilience Scale were used to conduct the questionnaire survey. Pearson correlation analysis was used for correlation analysis and AMOS 23.0 was used to establish the structural equation. Results　The total scores of medical treatment adherence, quality of life, and resilience were (70.98±10.72) points, (70.74±8.70) points, and (60.46±12.00) points respectively. The patients' resilience was positively correlated with medical treatment adherence (r=0.308, P=0.001) and quality of life (r=0.379, P<0.001), and the medical treatment adherence was positively correlated with quality of life (r=0.314, P=0.001). The resilience played a part of mediating effect between medical treatment adherence and quality of life, with a mediating effect value of 0.187. Conclusion　Improving resilience among MHD patients can enhance their medical treatment adherence and quality of life.

Key words: Hemodialysis, Resilience, Medical treatment adherence, Quality of life

摘要： 目的　探讨心理弹性在维持性血液透析患者治疗依从性与生活质量间的中介作用。方法　采用横断面研究法，选取2021年3月至5月广东省中医院104例行维持性血液透析的慢性肾脏病患者，采用治疗依从性量表、肾脏疾病生活质量简表和中文版心理弹性量表进行问卷调查。采用Pearson相关分析进行相关性分析和AMOS 23.0建立结构方程。结果　104例患者的治疗依从性总分为（70.98±10.72）分，生活质量总分为（70.74±8.70）分，心理弹性总分为（60.46±12.00）分；患者心理弹性与治疗依从性（r=0.308，P=0.001）和生活质量（r=0.379，P<0.001）呈正相关，治疗依从性与生活质量也呈正相关（r=0.314，P=0.001）；心理弹性在治疗依从性与生活质量之间起部分中介效应，中介效应值为0.187。结论　改善血液透析患者的心理弹性，能够提高其治疗依从性和生活质量。

关键词: 血液透析, 心理弹性, 治疗依从性, 生活质量