One case of overlap syndrome complicated with cerebral infarction

doi:10.3760/cma.j.cn441417-20240801-02029

Abstract

Abstract:

This article reports one patient with newly diagnosed overlap syndrome whose cardiolipin antibodies and lupus anticoagulants were negative. During the patient's oral rivaroxaban anticoagulant treatment, he had cerebral infarction three times (in different parts of the same cerebral blood vessel) within one month. The patient is currently receiving relevant treatment in another hospital. This tells us that when clinicians encounter patients with clinical symptoms that are highly suspected of antiphospholipid antibody syndrome, but their antiphospholipid antibodies and lupus anticoagulants are negative, they should still actively search for non-standard antibodies and screen for hereditary thrombophilia.

Key words:

Overlap syndrome, Cerebral , infarction, Systemic lupus erythematosus, Lupus nephritis

摘要：

本文报道1例新发重叠综合征患者，其心磷脂抗体、狼疮抗凝物检查均为阴性，在口服利伐沙班抗凝治疗期间，1个月内突发3次脑梗死（同一根脑血管不同部位），目前仍在外院接受相关治疗。提示，当临床医生遇到临床症状高度疑似抗磷脂抗体综合征，但抗心磷脂抗体、狼疮抗凝物均为阴性时，仍应积极外送寻找非标准外抗体，并进行遗传性易栓症的筛查。

关键词:

重叠综合征, 脑梗死, 系统性红斑狼疮, 狼疮性肾炎

Yan Xuantao, Ren Jie.

One case of overlap syndrome complicated with cerebral infarction [J]. International Medicine and Health Guidance News, 2025, 31(2): 318-322.

闫绚韬任洁.

重叠综合征合并脑梗死1例 [J]. 国际医药卫生导报, 2025, 31(2): 318-322.

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