Abstract: Objective　To analyze the positive effects of pulmonary rehabilitation training combined with drug therapy on lung function and quality of life in patients with chronic obstructive pulmonary disease (COPD) in stable stage. Methods　From January 2018 to December 2021, 100 patients who were clearly diagnosed with COPD in Panyu Hospital of Chinese Medicine were evaluated as stable after discharge, and they were divided into an intervention group and a control group with the random number table method. In the intervention group, the male to female ratio was 30∶20, the age was (64.38±5.86) years old, and the course of disease was (7.61±2.12) years; in the control group, the male to female ratio was 31∶19, the age was (65.12±5.75) years old, and the course of disease was (7.74±2.06) years. The control group received conventional drug therapy, and the intervention group received conventional therapy and pulmonary rehabilitation therapy. The lung function and quality of life were compared between the two groups. SPSS 25.0 software was used to compare the differences in the observation indicators, t test was used for the measurement data, and χ² test was used for the count data. Results　After 6 months of treatment, the forced expiratory volume in one second (FEV₁), ratio of forced expiratory volume in one second to forced vital capacity (FEV₁/FVC), and 6-minute walking distance (6MWD) in both groups were higher than those before treatment, and those in the intervention group were higher than those in the control group [(62.79±9.10)% vs. (57.90±9.74)%, (67.07±8.29)% vs. (61.70±8.97)%, (456.24±37.91) m vs. (415.17±29.27) m], with statistically significant differences (all P<0.05). After 6 months of treatment, the modified Medical Research Council Dyspnea Scale (mMRC) scores of the two groups were lower than those before treatment, and that in the intervention group was lower than that in the control group [(0.92±0.60) points vs. (1.51±0.45) points], with statistically significant differences (all P<0.05). After 6 months of treatment, the scores of respiratory symptoms, activity, and disease effect dimensions of St George's Respiratory Questionnaire (SGRQ) in the two groups were lower than those before treatment, and those in the intervention group were lower than those in the control group, with statistically significant differences (all P<0.05). Conclusion　Pulmonary rehabilitation therapy can significantly improve the levels of lung function and quality of life in patients with stable COPD, and it is worth promoting on the basis of conventional treatment.

Key words: Pulmonary rehabilitation, Stable COPD, Lung function, Quality of life

摘要： 目的　分析探讨肺康复训练联合药物治疗对稳定期慢性阻塞性肺疾病（chronic obstructive pulmonary disease，COPD）患者肺功能和生存质量的影响。方法　以2018年1月至2021年12月从广州市番禺区中医院出院的稳定期COPD患者100例为研究对象，采用随机数字表法分成干预组和对照组，每组50例。干预组男女比例30∶20，年龄（64.38±5.86）岁，病程（7.61±2.12）年；对照组男女比例31∶19，年龄（65.12±5.75）岁，病程（7.74±2.06）年。对照组接受常规药物治疗，干预组接受常规治疗+肺康复治疗。对比两组患者肺功能及生存质量指标。采用SPSS 25.0软件比较各观察指标的差异，计量资料采用t检验，计数资料采用χ²检验。结果　治疗6个月后，两组一秒用力呼气容积（FEV₁）、一秒用力呼气容积占用力肺活量的比率（FEV₁/FVC）、6分钟步行距离（6MWD）均高于治疗前，且干预组高于对照组［（62.79±9.10）%比（57.90±9.74）%、（67.07±8.29）%比（61.70±8.97）%，（456.24±37.91）m比（415.17±29.27）m］，差异均有统计学意义（均P<0.05）；两组改良版呼吸困难量表（mMRC）评分均低于治疗前，且干预组低于对照组［（0.92±0.60）分比（1.51±0.45）分］，差异均有统计学意义（均P<0.05）；两组圣乔治呼吸问卷（SGRQ）呼吸症状、活动能力、疾病影响3个维度评分均低于治疗前，且干预组低于对照组，差异均有统计学意义（均P<0.05）。结论　肺康复治疗可显著提高稳定期COPD患者肺功能和生活质量水平，值得在常规治疗基础上实施推广。

关键词: 肺康复, 稳定期COPD, 肺功能, 生活质量