关键词:

腹腔镜, 吲哚菁绿, 近红外显像技术, 左半结肠癌

Abstract:

Objective　To explore the application value of indocyanine green-near infrared (ICG-NIR) imaging technology in laparoscopic radical resection of left-sided colon cancer. Methods　A total of 90 patients who underwent laparoscopic left hemicolectomy at Jiangmen Wuyi Hospital of Chinese Medicine from May 2022 to March 2025 were selected as the research subjects. Using the random number table method, the patients were divided into the control group and the observation group, with 45 cases in each group. There were 31 males and 14 females in the control group, aged (53.21±5.28) years, course of the disease (1.63±0.32) years. There were 32 males and 13 females in the observation group, aged (54.39±5.14) years, course of the disease (1.61±0.28) years. The control group did not use indocyanine green (ICG) solution as the tracer for laparoscopic surgery, while the observation group used ICG solution as the tracer for laparoscopic surgery. The perioperative indicators were compared between the two groups (intraoperative blood loss, operation duration, postoperative exhaust time, and total hospital stay), the postoperative lymph node dissection situation (number of lymph nodes detected, number of positive lymph nodes, and lymph node metastasis), and the postoperative complication occurrence (anastomotic leakage, incision infection, and pulmonary infection). Independent sample t test, and χ² test were used for statistical analysis. Results　The intraoperative blood loss in the observation group was less than that in the control group [(106.45±4.85) ml vs. (150.56±5.23) ml], and the operation duration, postoperative exhaust time, and total hospital stay were all shorter [(101.45±4.81) min vs. (112.56±4.67) min, (2.14±1.12) d vs. (3.56±1.25) d, (8.46±1.64) d vs. (12.15±1.78) d] (all P<0.05). There was no statistically significant difference in the number of positive lymph nodes between the two groups (P>0.05). The number of lymph nodes detected in the observation group was higher than that in the control group [(16.42±2.14) vs. (12.21±2.23)], and the proportion of lymph node metastasis in the observation group was lower than that in the control group [28.89% (13/45) vs. 51.11% (23/45)] (both P<0.05). The total incidence of postoperative complications in the observation group was lower than that in the control group [4.44% (2/45) vs. 17.78% (8/45)] (P<0.05). Conclusions　The ICG-NIR imaging technique can accurately locate the tumor and its boundaries during laparoscopic radical resection of left-sided colon cancer. It can shorten the operation duration, reduce the amount of bleeding, increase the number of lymph nodes detected, decrease the proportion of patients with lymph node metastasis and the incidence of postoperative complications.

Key words:

Laparoscopy, Indocyanine green, Near infrared imaging technology, Left-sided colon cancer