国际医药卫生导报 ›› 2025, Vol. 31 ›› Issue (10): 1737-1742.DOI: 10.3760/cma.j.cn441417-20241208-100032

• 护理研究 • 上一篇    下一篇

多轨护理模式对干细胞治疗瘢痕的影响

张士歆1  李钢1  李迎辉2,3  程定1  任拥媛1  赵羽佳1  白杨1  王坤1   

  1. 1天津医科大学第二医院整形与医疗美容科,天津 300211;2中国医学科学院血液病医院(中国医学科学院血液学研究所)血液与健康全国重点实验室 国家血液系统疾病临床医学研究中心 细胞生态海河实验室,天津 300020;3天津医学健康研究院,天津 301600

  • 收稿日期:2024-12-08 出版日期:2025-05-15 发布日期:2025-05-22
  • 通讯作者: 李钢,Email:Ligang741012@163.com
  • 基金资助:

    国家自然科学基金(82370120)

Impact of multi-track specialized nursing mode based on motivation-behavior transformation on postoperative scar treatment with mesenchymal stem cells 

Zhang Shixin1, Li Gang1, Li Yinghui2,3, Cheng Ding1, Ren Yongyuan 1, Zhao Yujia1, Bai Yang1, Wang Kun1   

  1. 1 Department of Plastic and Medical Cosmetology, The Second Hospital of Tianjin Medical University, Tianjin 300211, China; 2 National Key Laboratory of Hematology and Health, National Clinical Research Center for Hematological Diseases, Haihe Laboratory of Cell Ecology, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences, Tianjin 300020, China; 3 Tianjin Academy of Medical Health, Tianjin 301600, China

  • Received:2024-12-08 Online:2025-05-15 Published:2025-05-22
  • Contact: Li Gang, Email: Ligang741012@163.com
  • Supported by:

    National Natural Science Foundation (82370120)

摘要:

目的 探讨动机行为转化下的多轨道专科护理模式对间充质干细胞治疗瘢痕患者的影响。方法 本研究方案按随机、前瞻性、单中心临床研究方法设计。选取2021年5月至2024年4月天津医科大学第二医院收治的80例瘢痕患者进行前瞻性研究,均采用间充质干细胞治疗,通过单双号抽签方式分组后,每组40例。对照组:男、女分别为23例、17例,年龄(57.78±5.45)岁。观察组:男、女分别为21例、19例;年龄(57.56±5.39)岁。对照组采用常规护理,观察组采用动机行为转化下的多轨道专科护理模式,比较2组患者的心理状态评分、生活质量评分、护理前后希望水平。采用χ2检验、t检验进行统计学分析。结果 干预2个月后,观察组负性情绪评分低于对照组(11.31±2.12比      16.18±3.18),差异有统计学意义(P<0.001);正性情绪评分高于对照组(25.34±5.12比20.23±5.03),差异有统计学意义(P<0.001);观察组躯体功能、心理功能、社会功能及物质生活状态等维度评分均高于对照组[(86.45±8.1比80.34±8.45、87.58±8.07比80.13±7.45、85.21±8.18比80.23±7.34、75.82±7.36比70.57±7.26),差异均有统计学意义(均P<0.001);观察组希望水平评分高于对照组(38.32±5.12比30.18±5.18),差异有统计学意义(P<0.001)。结论 采用动机行为转化下的多轨道专科护理模式干预间充质干细胞治疗瘢痕患者不仅可帮助其调节心理状态,还可提升其希望水平,使其生活品质得到一定程度提升。

关键词: 间充质干细胞,  ,  , 动机行为转化,  ,  , 多轨道专科护理

Abstract:

Objective To analyze the effect of the multi-track specialized nursing mode based on motivation-behavior transformation for scar patients treated with mesenchymal stem cells. Methods This was a random, prospective, and single-center clinical study. Eighty patients with scar treated at The Second Hospital of Tianjin Medical University from May 2021 to April 2024 were selected for this study. All the patients were treated with mesenchymal stem cells. The patients were divided into a control group and an observation group by lottery, with 40 cases in each group. There were 23 males and 17 females in the control group; they were  (57.78±5.45) years old. There were 21 males and 19 females in the observation group; they were  (57.56±5.39) years old. The control group took conventional nursing, and the observation group were intervened by the multi-track specialized nursing mode based on motivation-behavior transformation. The scores of psychological status, life quality, and hope level before and after the intervention were compared between the two groups. χ2 test and t test were used for statistical analysis . Results After 2 months of intervention, the observation group showed significantly lower negative emotion score compared to the control group (11.31±2.12 vs. 16.18±3.18, P<0.001, and significantly higher positive emotion score (25.34±5.12 vs. 20.23±5.03, P<0.001. Additionally, the observation group demonstrated significantly higher score across all quality-of-life dimensions, including physical function (86.45±8.1 vs. 80.34±8.45), psychological function (87.58±8.07 vs. 80.13±7.45), social function (85.21±8.18 vs. 80.23±7.34)], and material living conditions (75.82±7.36 vs. 70.57±7.26) (all P<0.001). Furthermore, the observation group exhibited significantly higher hope levels than the control group (38.32±5.12 vs. 30.18±5.18, P<0.001). Conclusion The effect of the multi-track specialized nursing mode based on motivation-behavior transformation for scar patients treated with mesenchymal stem cells can not only regulate their psychological status, but also improve their hope level and life quality.

Key words:  , Mesenchymal stem cells,  , Motivation-behavior transformation,  , Multi-track specialized nursing