以广泛骨髓坏死起病的儿童伯基特白血病1例并文献复习

doi:10.3760/cma.j.issn.1007-1245.2024.15.027.

国际医药卫生导报 ›› 2024, Vol. 30 ›› Issue (15): 2598-2601.DOI: 10.3760/cma.j.issn.1007-1245.2024.15.027.

以广泛骨髓坏死起病的儿童伯基特白血病1例并文献复习

丁慧郭庆伟李府杨晓梅

山东大学附属儿童医院济南市儿童医院血液肿瘤科，济南　250022

收稿日期:2024-03-04 出版日期:2024-08-01 发布日期:2024-09-02
通讯作者: 杨晓梅，Email：yangxiaomeijnetyy@163.com
基金资助:
山东省医药卫生科技发展计划（202106010191）

One child with Burkitt leukemia and onset of extensive bone marrow necrosis and review of literatures

Ding Hui, Guo Qingwei, Li Fu, Yang Xiaomei

Department of Hematology and Oncology, Children's Hospital Affiliated to Shandong University, Jinan Children's Hospital, Jinan 250022, China

Received:2024-03-04 Online:2024-08-01 Published:2024-09-02
Contact: Yang Xiaomei, Email: yangxiaomeijnetyy@163.com
Supported by:
Program for Development of Medical and Health Science and Technology in Shandong Province (202106010191)

摘要/Abstract

摘要：

伯基特淋巴瘤以腹部发病最常见，其次见于头部和颈部，骨髓肿瘤细胞超过25%则成为伯基特白血病，但以广泛骨髓坏死（BMN）起病罕见，诊断困难。本文回顾性分析1例以广泛BMN起病的伯基特白血病患儿的临床特点、诊疗经过及预后，并进行文献总结。

关键词:

骨髓坏死, 儿童, 伯基特白血病, 伯基特淋巴瘤, 文献复习

Abstract:

Burkitt lymphoma most commonly occurs in the abdomen, followed by the head and neck. It is defined as Burkitt leukemia when bone marrow tumor cells exceed 25%, but it is rare to start with extensive bone marrow necrosis (BMN) and difficult to diagnose. In this paper, the clinical features, diagnosis, treatment, and prognosis of a child with Burkitt leukemia complicated with extensive BMN are retrospectively analyzed, and the relevant literatures are summarized.

Key words:

Bone marrow necrosis, Children, Burkitt leukemia, Burkitt lymphoma, Review of literatures

丁慧郭庆伟李府杨晓梅.

以广泛骨髓坏死起病的儿童伯基特白血病1例并文献复习 [J]. 国际医药卫生导报, 2024, 30(15): 2598-2601.

Ding Hui, Guo Qingwei, Li Fu, Yang Xiaomei.

One child with Burkitt leukemia and onset of extensive bone marrow necrosis and review of literatures [J]. International Medicine and Health Guidance News, 2024, 30(15): 2598-2601.

参考文献

[1] Jaffe ES. The 2008 WHO classification of lymphomas: implications for clinical practice and translational research[J].Hematology Am Soc Hematol Educ Program,2009:523-531.DOI:10.1182/asheducation-2009.1.523.
[2] Ferry JA. Burkitt's lymphoma: clinicopathologic features and differential diagnosis[J].Oncologist,2006,11(4):375-383.DOI:10.1634/theoncologist.11-4-375.
[3] Mbulaiteye SM, Biggar RJ, Bhatia K, et al. Sporadic childhood burkitt lymphoma incidence in the united states during 1992-2005[J].Pediatr Blood Cancer,2009,53(3):366-370.DOI:10.1002/pbc.22047.
[4] Mead GM, Barrans SL, Qian W, et al. A prospective clinicopathologic study of dose-modified CODOX-M/IVAC in patients with sporadic burkitt lymphoma defined using cytogenetic and immunophenotypic criteria (MRC/NCRI LY10 trial)[J].Blood,2008,112(6):2248-2260.DOI:10.1182/blood-2008-03-145128.
[5] Goldman S, Smith L, Anderson JR, et al. Rituximab and FAB/LMB 96 chemotherapy in children with Stage Ⅲ/Ⅳ B-cell non-Hodgkin lymphoma: a children's oncology group report[J].Leukemia,2013,27(5):1174-1177.DOI:10.1038/leu.2012.255.
[6] Goldman S, Smith L, Galardy P, et al. Rituximab with chemotherapy in children and adolescents with central nervous system and/or bone marrow-positive Burkitt lymphoma/leukaemia: a children's oncology group report[J].Br J Haematol,2014,167(3):394-401.DOI:10.1111/bjh.13040.
[7] Wool GD, Deucher A. Bone marrow necrosis: ten-year retrospective review of bone marrow biopsy specimens[J].Am J Clin Pathol,2015,143(2):201-213.DOI:10.1309/AJCP0TN1MCMOLMPK.
[8] Wade LJ, Stevenson LD. Necrosis of the bone marrow with fat embolism in sickle cell anemia[J].Am J Pathol,1941,17(1):47-54.
[9] Deucher A, Wool GD. How I investigate bone marrow necrosis[J].Int J Lab Hematol,2019,41(5):585-592.DOI:10.1111/ijlh.13091.
[10] Chen R, Wu J, Yang J, et al. Analysis and clinical characteristics of 23 cases of Bone Marrow Necrosis[J].Clin Lymphoma Myeloma Leuk,2021,21(4):e356-e364.DOI:10.1016/j.clml.2020.12.001.
[11] Lozano-Chinga M, Draper L, George TI, et al. Bone marrow necrosis in pediatric malignancies: 10-year retrospective review and review of literature[J].Pediatr Blood Cancer,2021,68(3):e28806.DOI:10.1002/pbc.28806.
[12] 林彩芹,杨玉,毛慧,等. 骨髓坏死患者的临床特点、预后因素及误诊分析[J]. 中国实验血液学杂志,2021,29(5):1637-1644.DOI:10.19746/j.cnki.issn1009-2137.　2021.05.042.
[13] Jandeaux LM, Eischen A, Grillon A, et al. Bone marrow necrosis induced by massive staphylococcus aureus infiltration[J]. Intensive Care Med,2022,48(6):746-747.DOI:10.1007/s00134-022-06619-y.
[14] Harada N, Nishimoto M, Ikemoto A, et al. Recurrence of acute lymphoblastic leukemia with bone marrow necrosis: a case report and review of the literature on the MRI features of bone marrow necrosis[J].Intern Med,2021,60(7):1083-1088.DOI:10.2169/internalmedicine.　5815-20.
[15] Hilal T, Bansal P, Kelemen K, et al. Nivolumab-associated bone marrow necrosis[J].Ann Oncol,2018,29(2):513-514.DOI:10.1093/annonc/mdx643.
[16] Yarali N, Isik M, Arman-Bilir O, et al. Bone marrow necrosis in a patient following blinatumomab therapy[J].J Pediatr Hematol Oncol,2020,42(3):e167-e169.DOI:10.1097/MPH.0000000000001532.
[17] Paydas S, Koçak R, Zorludemir S, et al. Bone marrow necrosis in antiphospholipid syndrome[J].J Clin Pathol,1997,50(3):261-262.DOI:10.1136/jcp.50.3.261.
[18] Hui C, Bosch A, Mwizerwa O, et al. Case report: a case of bone marrow necrosis and hyperinflammation in a 10-year-old boy after plasmodium falciparum infection[J].Am J Trop Med Hyg,2023,109(3):611-615.DOI:10.4269/ajtmh.22-0550.
[19] Bosch A, Watad S, Willmott S, et al. Identifying and treating severe bone marrow necrosis and fat embolism syndrome in pediatric patients with sickle cell eisease: a case report[J].J Pediatr Hematol Oncol,2022,44(5):e884-e887.DOI:10.1097/MPH.0000000000002399.
[20] Marco DN, Cid J, Garrote M, et al. Diagnosis of bone marrow necrosis following severe vaso-occlusive crisis in patient with compound heterozygous sickle cell disease[J].Transfus Med Hemother,2023,50(4):360-364.DOI:10.1159/000529500.
[21] Mi R, Chen L, Wang L, et al. Bone marrow necrosis after treatment with blinatumomab for acute lymphoblastic leukemia: a case report[J].Asian J Surg,2024,47(3):1449-1450.DOI:10.1016/j.asjsur.2023.11.125.
[22] Le Calvez B, Camuset M, Debord C, et al. Bone marrow necrosis in childhood: the hunt for blasts[J].Int J Lab Hematol,2023,45(6):828-830.DOI:10.1111/ijlh.14151.
[23] 陈楠,朱建锋,陈朴,等. 18例骨髓坏死患者的临床特征及实验室检查结果分析[J]. 检验医学与临床,2022,19(2):149-152.DOI:10.3969/j.issn.1672-9455.2022.02.002.
[24] Elgamal BM, Rashed RA, Raslan HN. Prevalence of bone marrow necrosis in egyptian cancer patients referring to the national cancer institute[J].J Egypt Natl Canc Inst,2011,23(3):95-99.DOI:10.1016/j.jnci.2011.09.007.
[25] Kim DJ, Kim T, Jeong JY, et al. Poor prognostic impact of high serum ferritin levels in patients with a lower risk of diffuse large B cell lymphoma[J].Int J Hematol,2020,111(4):559-566.DOI:10.1007/s12185-019-02816-6.
[26] Asonitis N, Angelousi A, Zafeiris C, et al. Diagnosis, pathophysiology and management of hypercalcemia in malignancy: a review of the literature[J].Horm Metab Res,2019,51(12):770-778.DOI:10.1055/a-1049-0647.
[27] Ranathunga I, Muthumala NR, Kulathilake HWCK, et al. Extensive bone marrow necrosis: a rare presentation of acute lymphoblastic leukaemia[J].Case Rep Hematol,2020,2020:8889850.DOI:10.1155/2020/8889850.
[28] Xia J, Sun H, Yan Z, et al. Successful treatment of a patient with Philadelphia chromosome-positive acute lymphoblastic leukemia complicated by bone marrow necrosis and acute renal insufficiency: a case report[J].Mol Clin Oncol,2018,9(3):297-301.DOI:10.3892/mco.2018.1661.
[29] Pan Y, Wang X, Wang C, et al. Extensive bone marrow necrosis resolved by allogeneic umbilical cord blood mesenchymal stem cell transplantation in a chronic myeloid leukemia patient[J].Bone Marrow Transplant,2015,50(9):1265-1268.DOI:10.1038/bmt.2015.60.
[30] Ishitsuka K, Obara N, Suyama T, et al. Philadelphia chromosome-positive acute lymphoblastic leukemia complicated by bone marrow necrosis during consolidation chemotherapy[J].Rinsho Ketsueki,2020,61(5):462-467.DOI:10.11406/rinketsu.61.462.

以广泛骨髓坏死起病的儿童伯基特白血病1例并文献复习

One child with Burkitt leukemia and onset of extensive bone marrow necrosis and review of literatures

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