国际医药卫生导报 ›› 2022, Vol. 28 ›› Issue (13): 1919-1922.DOI: 10.3760/cma.j.issn.1007-1245.2022.13.030

• 综述 • 上一篇    

艾司氯胺酮在剖宫产中的应用及研究进展

杨世杰  刘树杰  曹芮  闫玉荣   

  1. 滨州医学院附属医院麻醉科,滨州 256600
  • 收稿日期:2022-03-25 出版日期:2022-07-01 发布日期:2022-07-01
  • 通讯作者: 闫玉荣,Email:bzmzyyr@163.com

Application and research progress of esketamine in cesarean section 

Yang Shijie, Liu Shujie, Cao Rui, Yan Yurong   

  1. Department of Anesthesiology, Binzhou Medical University Hospital, Binzhou 256600, China
  • Received:2022-03-25 Online:2022-07-01 Published:2022-07-01
  • Contact: Yan Yurong, Email: bzmzyyr@163.com

摘要: 艾司氯胺酮作为氯胺酮的同分异构体与消旋氯胺酮有相似的药理学特点,目前广泛应用于临床。与消旋氯胺酮相比,同等剂量下具有更强的镇痛和镇静效果,具有可控性更强、不良反应更少、不添加防腐剂、静脉及椎管内用药更安全等优点。

关键词: 艾司氯胺酮, 剖宫产, 作用机制, 临床应用

Abstract: Esketamine, an isomer of ketamine, has similar pharmacological characteristics to racemic ketamine, and is currently widely used in clinical practice. Compared with racemic ketamine, it has stronger analgesic and sedative effects at the same dose, and has the advantages of stronger controllability, fewer adverse reactions, no added preservatives, and safer intravenous and intraspinal administration.

Key words: Esketamine, Cesarean section, Mechanism, Clinical application