国际医药卫生导报 ›› 2024, Vol. 30 ›› Issue (17): 2936-2941.DOI: 10.3760/cma.j.issn.1007-1245.2024.17.023

• 临床研究 • 上一篇    下一篇

疏血通在急性脑梗死患者治疗中的临床效果研究

曹运红1  曾武成1  杜进林2   

  1. 1惠东县多祝镇增光卫生院内科,惠州 516300;2广东医科大学公共卫生学院流行病与卫生统计学系,东莞 523808

  • 收稿日期:2024-02-02 出版日期:2024-09-01 发布日期:2024-09-23
  • 通讯作者: 杜进林,Email:dujinlin@gdmu.edu.cn
  • 基金资助:

    广东省教育科学“十三五”规划2019年度高校哲学社会科学专项研究(2019GXJK226)

Effect of Shuxuetong injection for patients with acute cerebral infarction

Cao Yunhong1, Zeng Wucheng1, Du Jinlin2   

  1. 1 Department of Internal Medicine, Zengguang Health Center, Duozhu Town, Huidong County, Huizhou 516000, China; 2 Department of Epidemiology and Statistics, School of Public Health, Guangdong Medical University, Dongguan 523808, China

  • Received:2024-02-02 Online:2024-09-01 Published:2024-09-23
  • Contact: Du Jinlin, Email: dujinlin@gdmu.edu.cn
  • Supported by:

    Special Project of Philosophy and Social Science for Colleges and Universities of Guangdong Province Educational Science "Thirteenth Five-Year Plan" in 2019 (2019GXJK226)

摘要:

目的 探讨加用疏血通治疗急性脑梗死患者的临床效果。方法 采用完全随机对照设计,从惠东县多祝镇增光卫生院2022年9月至2023年4月收入的急性脑梗死患者中随机抽取86例,按照随机数字表法分为两组,各43例。对照组:男20例,年龄(60.63±2.39)岁;女23例,年龄(63.16±1.38)岁;采用常规治疗。疏血通组:男21例,年龄(58.08±2.35)岁;女22例,年龄(63.72±2.87)岁;在常规治疗基础上加用疏血通(静脉滴注,每日6 ml,加于250 ml生理盐水中缓慢滴入),7 d为1个疗程,共2个疗程。评估两组治疗后总有效率、满意率、不良反应率及体征指标、健康状况调查简表(SF-36)和中医症候指标评分。统计学方法采用秩和检验、χ2检验和t检验。结果 治疗后,疏血通组总有效率、治疗总满意率均高于对照组[95.35%(41/43)比81.40%(35/43)、97.67%(42/43)比79.07%(34/43)],差异均有统计学意义(χ2=4.07、7.24,均P<0.05)。对照组不良反应发生率高于疏血通组[27.91%(12/43)比9.30%(4/43)],差异有统计学意义(χ2=4.91,P<0.05)。两组治疗前体征指标、SF-36、中医证候指标评分差异均无统计学意义(均P>0.05);治疗后,疏血通组均优于对照组(均P<0.05)。结论 对急性脑梗死患者采用常规治疗方法加用疏血通治疗,临床疗效好,治疗满意率和有效率高,可推广。

关键词:

急性脑梗死, 临床效果, 疏血通

Abstract:

Objective To study the clinical effect of Shuxuetong injection in the treatment of patients with acute cerebral infarction. Methods Eighty-six patients with acute cerebral infarction treated at Zengguang Health Center from September 2022 to April 2023 were selected for the randomized controlled trial, and were divided into a control group and a Shuxuetong group by the random number table method, with 43 cases in each group. There were 20 males who were (60.63±2.39) years old and 23 females who were (63.16±1.38) years old in the control group. There were 21 males who were (58.08±2.35) years old and 22 females who were (63.72±2.87) years old in the Shuxuetong group. Both groups took routine treatment; in addition, the Shuxuetong group intravenously dripped 6 ml Shuxuetong added into 250 ml normal saline. Seven days were one treatment course, and both groups were treated 2 courses. The total effective rates, satisfaction rates, incidences of adverse reactions, physical signs, and scores of the Mos 36-Item Short Form Health Survey (SF-36) and traditional Chinese medicine symptoms were compared between the two groups by the rank sum test, χ2 test, and t test. Results After the treatment, the total effective rate and comprehensive treatment satisfaction rate in the Shuxuetong group were higher than those in the control group [95.35% (41/43) vs. 81.40% (35/43) and 97.67% (42/43) vs. 79.07% (34/43)], with statistical differences (χ2=4.07 and 7.24; both P<0.05). The incidence of adverse reactions in the control group was higher than that in the control group [27.91% (12/43) vs. 9.30% (4/43)], with a statistical difference (χ2=4.91; P<0.05). Before the treatment, there were no statistical differences in the physical signs and the scores of SF-36 and traditional Chinese medicine symptoms between the two groups (all P>0.05); after the treatment, the physical signs and the scores of SF-36 and traditional Chinese medicine symptoms in the Shuxuetong group were better than those in the control group (P<0.05). Conclusion Routine treatment combined with Shuxuetong for patients with acute cerebral infarction is effective, with a high satisfaction rate and an effective rate, so it is worth being generalized.

Key words:

Acute cerebral infarction, Clinical effect, Shuxuetong