派特灵外用治疗跖疣的临床疗效

doi:10.3760/cma.j.issn.1007-1245.2024.06.031

国际医药卫生导报 ›› 2024, Vol. 30 ›› Issue (6): 1028-1031.DOI: 10.3760/cma.j.issn.1007-1245.2024.06.031

派特灵外用治疗跖疣的临床疗效

刘苑玲¹ 陈文艺² 吴雪琳² 胡燕卿² Yaqoob Muhammad Danish² 刘康兴²

¹南方医科大学第三附属医院普通外科，广州　510630；²南方医科大学第三附属医院皮肤性病科，广州　510630

收稿日期:2023-12-20 出版日期:2024-03-01 发布日期:2024-03-29
通讯作者: 刘康兴，Email：lkxfwj2006@163.com
基金资助:
广东省中医药局科研项目（20212147）

Clinical efficacy of treatment to plantar wart by Paiteling

Liu Yuanling¹, Chen Wenyi², Wu Xuelin², Hu Yanqing², Yaqoob Muhammad Danish², Liu Kangxing²

¹General Surgery, The 3rd Affiliated Hospital of Southern Medical University, Guangzhou 510630, China; ²Department of Dermatology and Venereology, The 3rd Affiliated Hospital of Southern Medical University, Guangzhou 510630, China

Received:2023-12-20 Online:2024-03-01 Published:2024-03-29
Contact: Liu Kangxing, Email: lkxfwj2006@163.com
Supported by:
Scientific Research Project of Guangdong Provincial Bureau of Traditional Chinese Medicine (20212147)

摘要/Abstract

摘要：

目的　观察派特灵外用治疗跖疣的临床疗效。方法　选取2019年1月至2022年12月南方医科大学第三附属医院确诊的跖疣患者150例，采用随机分配的方式，50例患者采取派特灵外敷治疗，50例患者采用CO₂激光治疗，50例患者采用液氮冷冻治疗，并分别于治疗结束后4周、12周进行随访，观察3组临床疗效、复发情况。采用χ²检验、F检验。结果　派特灵组50例患者年龄（30.25±10.52）岁，其中男性27例、女性23例，皮损单发15例、两处及以上部位35例；CO₂激光组50例患者年龄（28.65±11.25）岁，其中男性30例、女性20例，皮损单发20例、两处及以上部位30例；液氮冷冻组50例患者年龄（25.15±9.65）岁；其中男性25例、女性25例，皮损单发20例、两处及以上部位30例。治疗后4周，派特灵组临床有效率为94.0%（47/50），CO₂激光组临床有效率为84.0%（42/50），液氮冷冻组临床有效率为80.0%（40/50），3组比较差异有统计学意义（χ²=6.258，P=0.025），CO₂激光组与液氮冷冻组差异无统计学意义（χ²=0.619，P=0.532）。治疗后12周，派特灵组临床有效率为88.0%（44/50），CO₂激光组临床有效率为78.0%（39/50），液氮冷冻组临床有效率为72.0%（36/50），3组比较差异有统计学意义（χ²=5.893，P=0.031），CO₂激光组与液氮冷冻组差异无统计学意义（χ²=2.021，P=0.328）。结论　派特灵能有效地治疗跖疣，减少复发率，创伤和不良反应较小，可广泛应用于临床治疗。

关键词:

跖疣, 人乳头瘤病毒, 派特灵, 临床疗效

Abstract:

Objective　To observe the clinical effect of Pateling to cure plantar wart. Methods　A total of 150 patients with plantar wart in the 3rd Affiliated Hospital of Southern Medical University from January 2019 to December 2022 were selected and were randomly assigned into three groups. Fifty patients were treated with Paiteling, 50 patients were treated with CO₂ laser, and 50 patients were treated with liquid nitrogen cryotherapy. Follow-up was performed 4 weeks and 12 weeks after the end of treatment to observe the clinical efficacy and recurrence of the 3 groups. χ² test and F test were used. Results　In the Paiteling group, 50 patients were (30.25±10.52) years old, including 27 males and 23 females, 15 cases of single lesion and 35 cases of two or more lesions. In the CO₂ laser group, 50 patients were (28.65±11.25) years old, including 30 males and 20 females, 20 cases of single lesion and 30 cases of two or more lesions. In the liquid nitrogen cryotherapy group, 50 patients were (25.15±9.65) years old, including 25 males and 25 females, 20 cases of single lesion and 30 cases of two or more lesions. Four weeks after treatment, the clinical effective rate was 94.0% (47/50) in the Paiteling group, 84.0% (42/50) in the CO₂ laser group, and 80.0% (40/50) in the liquid nitrogen cryotherapy group, and the difference was statistically significant among the three groups (χ²=6.258, P=0.025), but there was no statistically significant difference between the CO₂ laser group and the liquid nitrogen cryotherapy group (χ²=0.619, P=0.532). Twelfth weeks after treatment, the clinical effective rate was 88.0% (44/50) in the Paiteling group, 78.0% (39/50) in the CO₂ laser group, and 72.0% (36/50) in the liquid nitrogen cryotherapy group, and the difference was statistically significant among the three groups (χ²=5.893, P=0.031), but there was no statistically significant difference between the CO₂ laser group and the liquid nitrogen cryotherapy group (χ²=2.021, P=0.328). Conclusion　Paiteling can cure plantar wart effectively, which can reduce recurrence rate and can be used for clinic as a new therapy to treat plantar wart.

Key words:

Plantar wart, Human papilloma virus, Paiteling, Clinical effects

刘苑玲陈文艺吴雪琳胡燕卿 Yaqoob Muhammad Danish 刘康兴.

派特灵外用治疗跖疣的临床疗效 [J]. 国际医药卫生导报, 2024, 30(6): 1028-1031.

Liu Yuanling, Chen Wenyi, Wu Xuelin, Hu Yanqing, Yaqoob Muhammad Danish, Liu Kangxing.

Clinical efficacy of treatment to plantar wart by Paiteling [J]. International Medicine and Health Guidance News, 2024, 30(6): 1028-1031.

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派特灵外用治疗跖疣的临床疗效

Clinical efficacy of treatment to plantar wart by Paiteling

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