关键词:

重症监护病房, 呼吸机相关性肺炎, 危险因素, 预测模型

Abstract:

Objective　To analyze the risk factors of ventilator-associated pneumonia (VAP) in patients at respiratory intensive care unit (RICU), and to construct a risk prediction model and draw a graph. Methods　A total of 796 patients who received mechanical ventilation for more than 48 h and had complete clinical examination data in RICU, Inner Mongolia People's Hospital from January 1, 2020 to December 31, 2022 were selected as the study objects. The patients were divided into a VAP group (285 cases) and a non-VAP group (511 cases) according to whether the patients had infectious pneumonia after receiving mechanical ventilation for more than 48 h or removing the machines and pulling out the tubes within 48 h. The risk factors of VAP were analyzed by the univariate and multivariate logistic analyses. The R software was used to draw the nomograms. Results　The incidence of VAP in the patients was 35.80% (285/796). Cerebral infarction, antibiotics combination, central venous catheter, urinary catheter, ventilator using days, and antibiotics using days were the independent risk factors of VAP (OR=1.752, 2.406, 4.596 4.503, 1.209, and 1.093; all P<0.05). The area under the model's receiver operating characteristic curve was 0.925 (95%CI 0.907-0.944). Conclusions　The independent risk factors of VAP in RICU should be paid attention to and evaluated in time in clinical work. The predictive model for the risk factors of VAP is effective, and can provide some references in the prediction of the risk of patients with VAP.

Key words:

Intensive care unit, Ventilator-associated pneumonia, Risk factors, Predictive model