关键词:

慢性疾病, 不良反应, 静脉采血, 危险因素

Abstract:

Objective　To investigate the occurrence of adverse reactions of blood collection in patients with chronic diseases undergoing venous blood collection and to explore the influencing factors. Methods　A cross-sectional survey was conducted to investigate the occurrence of adverse reactions of blood collection in patients with chronic diseases who were admitted to the Health Management Department of The 73rd Army Group Hospital, PLA from January 2021 to June 2022. The patients' clinical data were collected, and the factors influencing the occurrence of adverse reactions were analyzed by univariate and multivariate binary logistic regression analysis. χ² test and t test were used. Results　(1) A total of 3 246 patients with chronic diseases who had undergone venous blood collection completed the study. There were 1 749 males and 1 497 females, aged 43-94 (69.76±14.46) years. There were 72 cases of adverse reactions, with an incidence of 2.22%. The top three types of adverse reactions were needle sickness in 26 cases (36.11%), oedema at the puncture site in 14 cases (19.44%), and local haematoma/bleeding in 12 cases (16.67%). There were 46 cases (63.89%) of immediate response and 26 cases (36.11%) of delayed response. There were 57 cases (79.17%) of mild adverse reactions, 14 cases (19.44%) of moderate adverse reactions, and 1 case (1.39%) of severe adverse reactions. (2) Multivariate logistic analysis showed that age (OR=1.018, 95%CI 1.011-1.025, P=0.045), gender (OR=1.476, 95%CI 1.145-1.903, P=0.038), cerebrovascular disease (OR=1.306, 95%CI 1.141-1.495, P=0.026), and number of punctures (OR=1.249, 95%CI 1.184-1.317, P=0.034) were the influencing factors of adverse reactions in patients with chronic diseases undergoing venous blood collection. Conclusions　The adverse reactions of blood collection in patients with chronic diseases undergoing venous blood collection are mainly mild, while the immediate adverse reactions account for a relatively high proportion. Needle sickness, oedema at the puncture site, and local haematoma/bleeding are the main types of adverse reactions. Advanced age, female, cerebrovascular disease, and number of punctures are the risk factors of adverse reactions of venous blood collection in patients with chronic diseases.

Key words:

Chronic diseases, Adverse reactions, Venous blood collection, Risk factors