国际医药卫生导报 ›› 2025, Vol. 31 ›› Issue (15): 2466-2470.DOI: 10.3760/cma.j.cn441417-20250609-15001

• 麻醉镇痛专栏 •    下一篇

微创介入治疗癌症晚期患者疼痛的 研究进展

戴伟1 崔冬梅2 王文君3 杨文静4 马世刚5 张艳英6 王涛3 满涛7   

  1. 1 枣庄市胸科医院(枣庄市肿瘤医院)外一科,滕州 277500;2 枣庄市胸科医院(枣庄市 肿瘤医院)内一科,滕州 277500;3 枣庄市胸科医院(枣庄市肿瘤医院)微创介入病房, 滕州 277500;4 枣庄市胸科医院(枣庄市肿瘤医院)内四科,滕州 277500;5 枣庄市胸科 医院(枣庄市肿瘤医院)外二科,滕州 277500;6 枣庄市胸科医院(枣庄市肿瘤医院) 检验科,滕州 277500;7 枣庄市胸科医院(枣庄市肿瘤医院)影像科,滕州 277500
  • 收稿日期:2025-06-09 出版日期:2025-08-01 发布日期:2025-08-21
  • 通讯作者: 杨文静,Email:515823168@qq.com
  • 基金资助:
    山东省医药卫生科技发展计划(202203020695)

Research progress of minimally invasive interventional therapy for pain in patients with advanced cancer

Dai Wei1 , Cui Dongmei2 , Wang Wenjun3 , Yang Wenjing4 , Ma Shigang5 , Zhang Yanying6 , Wang Tao3 , Man Tao7   

  1. 1 Department of Surgery, Zaozhuang Chest Hospital (Zaozhuang Tumor Hospital), Tengzhou 277500, China; 2 Department of Internal Medicine, Zaozhuang Chest Hospital (Zaozhuang Cancer Hospital), Tengzhou 277500, China; 3 Minimally invasive interventional ward, Zaozhuang Chest Hospital (Zaozhuang Cancer Hospital), Tengzhou 277500, China; 4 Fourth department of Internal Medicine, Zaozhuang Chest Hospital (Zaozhuang Tumor Hospital), Tengzhou 277500, China; 5 Second Department of Surgery, Zaozhuang Chest Hospital (Zaozhuang Cancer Hospital), Tengzhou 277500, China; 6 Department of Laboratory, Zaozhuang Chest Hospital (Zaozhuang Cancer Hospital), Tengzhou 277500, China; 7Department of Imaging, Zaozhuang Chest Hospital (Zaozhuang Tumor Hospital), Tengzhou 277500, China
  • Received:2025-06-09 Online:2025-08-01 Published:2025-08-21
  • Contact: Yang Wenjing,Email:515823168@qq.com
  • Supported by:
    Shandong Province Medical and Health Science and Technology Development Project (202203020695)

摘要:  癌性疼痛是癌症患者尤其是晚期癌症患者常见且严重影响生活质量的症状。传统药物 治疗存在诸多局限性,微创介入治疗作为新兴手段在癌性疼痛管理中逐渐凸显优势。本文综述了微 创介入治疗癌性疼痛患者的适应证和禁忌证、不同部位的常用方法(包括神经阻滞毁损术、经皮椎体 成形术、射频消融术、鞘内药物输注系统植入术等在癌症晚期疼痛治疗中的应用)、难治性癌性疼痛的 介入干预时机等,分析其原理、疗效、优势及相关风险,旨在为临床更好地选择和应用微创介入治疗癌 性疼痛提供参考,以提高患者生存质量。

关键词: 癌性疼痛, 微创介入治疗, 进展

Abstract: Cancer pain is a common and severe symptom that significantly affects the quality of life of cancer patients, particularly those with advanced cancer. Traditional pharmacological treatments have many limitations; therefore, minimally invasive interventional therapies have gradually shown advantages in the management of cancer pain. This article reviews the indications and contraindications for minimally invasive interventional treatment in cancer pain patients, commonly used methods for different anatomical sites, including nerve block and ablation,percutaneous vertebroplasty, radiofrequency ablation, and intrathecal drug delivery system implantation for pain management in advanced cancer. It also discusses the timing of interventional interventions for refractory cancer pain, analyzing their principles, efficacy, advantages, and associated risks. The aim is to provide a reference for better selection and application of minimally invasive interventional therapies for cancer pain in clinical practice to improve patient quality of life.

Key words: Cancerous pain, Minimally invasive interventional therapy, Progress