瞬感扫描式葡萄糖监测系统在糖尿病性视网膜病变患者血糖波动中的应用

doi:10.3760/cma.j.cn441417-20250312-18010

国际医药卫生导报 ›› 2025, Vol. 31 ›› Issue (18): 3041-3044.DOI: 10.3760/cma.j.cn441417-20250312-18010

瞬感扫描式葡萄糖监测系统在糖尿病性视网膜病变患者血糖波动中的应用

张雪莲¹ 孟伟¹ 张敏¹ 沈洁¹ 王春红² 李珊珊¹ 常冰¹

¹徐州市第一人民医院内分泌科，徐州 221000；²徐州市眼科医院，徐州 221000

收稿日期:2025-03-12 出版日期:2025-09-15 发布日期:2025-09-26
通讯作者: 孟伟，Email：ylsna2013@163.com
基金资助:
江苏省卫生健康委科研项目（LGY2020026）

Application of flash glucose monitoring in blood glucose fluctuation of patients with diabetic retinopathy

Zhang Xuelian¹, Meng Wei¹, Zhang Min¹, Shen Jie¹, Wang Chunhong², Li Shanshan¹, Chang Bing¹

¹Department of Endocrinology, Xuzhou First People's Hospital, Xuzhou 221000, China; ²Xuzhou City Eye Hospital, Xuzhou 221000, China

Received:2025-03-12 Online:2025-09-15 Published:2025-09-26
Contact: Meng Wei, Email: ylsna2013@163.com
Supported by:
Scientific Research Project Supported by Jiangsu Health Commission (LGY2020026)

摘要/Abstract

摘要：

目的　探讨瞬感扫描式葡萄糖监测系统（FGM）在糖尿病性视网膜病变（DR）患者中的应用效果及对血糖波动水平的影响。方法　前瞻性研究，选取2023年10月至2024年3月徐州市第一人民医院收治的60例DR患者作为研究对象，根据干预方法不同分为两组，各30例。对照组男23例、女7例，年龄（53.74±12.96）岁，糖尿病病程（5.60±1.48）年，行常规干预；观察组男19例、女11例，年龄（52.18±10.09）岁，糖尿病病程（5.43±1.51）年，采用FGM配合个体化干预管理。对比两组患者干预前后血糖［空腹血糖（FPG）、餐后2 h血糖（2 hPG）、糖化血红蛋白（HbA1c）、葡萄糖在目标范围内时间（TIR）］、最佳矫正视力（BCVA）及患者自我管理能力水平。统计学方法采用t检验。结果　干预后，观察组FPG、2 hPG、HbA1c均低于对照组［（5.92±1.28）mmol/L比（6.58±1.10）mmol/L、（7.47±1.72）mmol/L比（8.53±1.84）mmol/L、（5.10±0.69）%比（5.67±0.82）%］，TIR、BCVA水平及糖尿病自我管理行为量表（SDSCA）总分均高于对照组［（72.30±7.26）%比（65.97±8.74）%、（0.53±0.18）logMAR比（0.42±0.17）logMAR、（47.68±9.30）分比（40.21±7.62）分］，差异均有统计学意义（t=2.142、2.305、2.913、3.051、2.433、3.403，均P<0.05）。结论　FGM用于DR患者效果显著，有助于改善血糖水平，减少血糖波动，提高患者自我管理能力。

关键词:

糖尿病视网膜病变, 瞬感扫描式葡萄糖监测系统, 血糖波动

Abstract:

Objective　To study the effect of flash glucose monitoring (FGM) for patients with diabetic retinopathy (DR) and its influence on blood glucose fluctuation. Methods　Sixty patients with DR treated at Xuzhou First People's Hospital from October 2023 to March 2024 were selected for the prospective study, and were divided into a control group and an observation group according to the intervention methods, with 30 cases in each group. There were 23 males and 7 females in the control group; they were (53.74±12.96) years old; their diabetic course was (5.60±1.48) years. There were 19 males and 11 females in the observation group; they were (52.18±10.09) years old; their diabetic course was (5.43±1.51) years. The control group received routine intervention. The observation group received FGM and personalized intervention management. The blood glucose [fasting plasma glucose (FPG), 2-hour postprandial plasma glucose (2 hPG), glycosylated hemoglobin (HbA1c), and time in range (TIR)], best corrected visual acuity (BCVA), and self-management ability levels before and after the intervention were compared between the two groups by t test. Results　After the intervention, the FPG, 2 hPG, and HbA1c in the observation group were lower than those in the control group [(5.92±1.28) mmol/L vs. (6.58±1.10) mmol/L, (7.47±1.72) mmol/L vs. (8.53±1.84) mmol/L, and (5.10±0.69)% vs. (5.67±0.82)%], and the TIR, BCVA, and total score of Summary of Diabetes Self-care Activities (SDSCA) were higher [(72.30±7.26)% vs. (65.97±8.74)%, (0.53±0.18) logMAR vs. (0.42±0.17) logMAR, and 47.68±9.30 vs. 40.21±7.62], with statistical differences (t=2.142, 2.305, 2.913, 3.051, 2.433, and 3.403; all P<0.05). Conclusion　Application of FGM in patients with DR is effective, and can improve their blood glucose levels and self-management ability and reduce blood glucose fluctuation.

Key words:

Diabetic retinopathy, Flash glucose monitoring, Blood glucose fluctuation

张雪莲孟伟张敏沈洁王春红李珊珊常冰.

瞬感扫描式葡萄糖监测系统在糖尿病性视网膜病变患者血糖波动中的应用 [J]. 国际医药卫生导报, 2025, 31(18): 3041-3044.

Zhang Xuelian, Meng Wei, Zhang Min, Shen Jie, Wang Chunhong, Li Shanshan, Chang Bing.

Application of flash glucose monitoring in blood glucose fluctuation of patients with diabetic retinopathy [J]. International Medicine and Health Guidance News, 2025, 31(18): 3041-3044.

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瞬感扫描式葡萄糖监测系统在糖尿病性视网膜病变患者血糖波动中的应用

Application of flash glucose monitoring in blood glucose fluctuation of patients with diabetic retinopathy

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