Objective To evaluate the impact of modified Kaitianmen therapy combined with five-tone therapy on the postoperative recovery and sleep quality in patients undergoing interventional treatment for coronary heart disease (CHD). Methods This prospective study included 120 patients with CHD who underwent interventional treatment at Xi'an People's Hospital and Xi'an Hospital of Traditional Chinese Medicine from February to October 2023. The patients were divided into a control group and an observation group by the random number table method, with 60 patients in each group. In the control group, there were 37 males and 23 females, aged (53.11±4.98) years, and the cardiac function grade was as follows: 5 cases of grade I, 12 cases of grade II, 25 cases of grade III, and 18 cases of grade IV. In the observation group, there were 41 males and 19 females, aged (50.51±5.14) years, and the cardiac function grade was as follows: 6 cases of grade I, 14 cases of grade II, 27 cases of grade III, and 13 cases of grade IV. The control group received modified Kaitianmen therapy, and the observation group received both modified Kaitianmen and five-tone therapy for a week. The rehabilitation outcomes, traditional Chinese medicine (TCM) syndrome score, psychological state [using the Symptom Checklist-90 (SCL-90)], and sleep quality [using the Pittsburgh Sleep Quality Index (PSQI)] were compared between the two groups before and one week after intervention. Independent sample t test and χ2 test were used. Results After intervention, the 6-min walking distance of the observation group was (413.14±36.67) m, which was longer than that of the control group [(364.68±30.70) m], and the left ventricular ejection fraction (LVEF) was (59.96±6.14)%, which was higher than that of the control group [(52.79±4.57)%], with statistically significant differences (both P<0.05). After intervention, the TCM scores of fatigue, chest tightness, shortness of breath, and chest pain in the observation group were (1.96±0.63) points, (2.76±0.43) points, (1.91±0.56) points, and (1.93±0.49) points, which were lower than those in the control group [(3.52±0.79) points, (3.88±0.50) points, (2.95±0.79) points, and (3.65±0.76) points]; the scores of anxiety, depression, interpersonal sensitivity, hostility, compulsion, paranoia, phobia, somatization, and mental illness of the SCL-90 were (1.96±0.20) points, (1.87±0.16) points, (1.72±0.17) points, (1.74±0.18) points, (1.84±0.18) points, (1.98±0.24) points, (2.38±0.32) points, (1.09±0.12) points, and (0.93±0.09) points, which were lower than those in the control group [(2.67±0.33) points, (2.36±0.33) points, (2.27±0.23) points, (2.19±0.20) points, (2.33±0.30) points, (2.72±0.39) points, (3.42±0.34) points, (1.57±0.16) points, and (1.43±0.17) points]; the scores of sleep duration, latency, sleep quality, daytime dysfunction, sleep disorders, hypnotic drugs, and sleep efficiency of the PSQI were (0.76±0.08) points, (0.91±0.06) points, (0.73±0.09) points, (0.97±0.10) points, (0.60±0.07) points, (0.86±0.07) points, and (0.78±0.09) points, which were lower than those in the control group [(1.78±0.51) points, (1.95±0.61) points, (1.65±0.29) points, (2.04±0.22) points, (1.28±0.13) points, (1.84±0.39) points, and (1.82±0.26) points], with statistically significant differences (all P<0.05). Conclusion The combination of modified Kaitianmen therapy and five-tone therapy can effectively improve the 6-min walking distance and LVEF, reduce the TCM syndrome score and negative emotions, and enhance the sleep quality in patients undergoing interventional treatment for CHD, thus promoting the postoperative recovery.