Abstract: Objective　To explore the application value of high resolution MRI (HR-MRI) in evaluating the characteristics of responsible intracranial vessel walls in patients with cerebral infarction. Methods　The clinical data and HR-MRI data of 80 patients with cerebral infarction admitted to Liaocheng Third People's Hospital from October 2020 to February 2022 were retrospectively analyzed. Among the patients, there were 67 males and 13 females. The patients were 22-75 (58.4±6.00) years old. There were 63 patients with hypertension, 44 patients with diabetes, 27 patients with hyperlipidemia, and 5 patients with atrial fibrillation. The data were processed using SPSS 20.0, and compared between the groups by χ², t, and rank sum tests. Results　The responsible vessels were middle cerebral artery (MCA) (52 cases) and basilar artery (BA) (28 cases). The plaque location was different in the two groups (χ²=9.881, P=0.020). Most plaques in the patients with MCA stenosis located on the dorsal and inferior walls, while most plaques in the patients with BA stenosis on the ventral and dorsal walls. The patients with MCA as the responsible vessels mainly had cortical and lacunar infarcts. Most of the lesions in the patients with BA as responsible vessels were parapontine and cerebellar hemisphere infarcts. Among the 80 patients, there were 52, 18, and 10 patients in early, middle, and late stages; of whom the intensities of plaques decreased in order. The proportion of the patients with grade 2 plaque enhancement in early stage was the highest (χ²=26.510, P=0.020). Conclusions　HR-MRI can help to clearly identify the characteristics of responsible intracranial vessel walls in patients with cerebral infarction. The shorter the time from onset to detection, the higher the degree of plaque enhancement. HR-MRI images are helpful for developing treatment plans of patients with cerebral infarction.

Key words: Cerebral infarction, High-resolution MRI, Characteristics of responsible intracranial vessel walls

摘要： 目的　探究高分辨率MRI（high resolution MRI，HR-MRI）在脑梗死患者颅内责任血管管壁特征评估中的应用价值。方法　回顾性选取2020年10月至2022年2月在聊城市第三人民医院接受治疗的80例脑梗死患者的临床资料，其中男67例、女13例，年龄22～75（58.4±6.00）岁，合并高血压者63例、糖尿病者44例、高脂血症者27例、心房颤动者5例。收集所有患者的临床就诊资料及HR-MRI影像资料，采用SPSS 20.0软件处理数据，组间比较采用χ²、t、秩和检验。结果　80例脑梗死患者中，52例患者的责任血管为大脑中动脉（MCA），28例为基底动脉（BA）。MCA狭窄患者位于背侧壁、下侧壁的斑块占比较高，BA狭窄患者的斑块则位于腹侧壁、背侧壁较多，两组患者的斑块位置差异有统计学意义（χ²=9.881，P=0.020）。责任血管为MCA的患者，多为皮层梗死灶、腔隙性梗死灶；责任血管为BA的患者，多为桥旁脑梗死、小脑半球梗死。80例患者中，早期、中期、晚期患者分别为52例、18例、10例，其斑块强度逐渐降低，早期患者的斑块2级强化占比最高（χ²=26.510，P<0.001）。结论　HR-MRI可清晰识别梗死患者颅内责任血管管壁特征，患者发病至检测的时间越短，其斑块强化程度越高，HR-MRI影像对于脑梗死患者治疗方案的制定具有一定指导意义。

关键词: 脑梗死, 高分辨MRI, 颅内责任血管管壁特征