International Medicine and Health Guidance News ›› 2024, Vol. 30 ›› Issue (19): 3184-3188.DOI: 10.3760/cma.j.issn.1007-1245.2024.19.004

• Digestive Tract Diseases • Previous Articles     Next Articles

Research progress of perioperative treatment for esophagogastric junction adenocarcinoma

Chen Xiaojiang, Li Yuanfang   

  1. Department of Gastric Surgery, Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangzhou 510060, China

  • Received:2024-07-23 Online:2024-10-01 Published:2024-10-17
  • Contact: 李元方,Email:liyuanf@sysucc.org.cn
  • Supported by:

    Guangdong Natural Science Foundation (2022A1515012458)

食管胃结合部腺癌围手术期治疗研究进展

陈小江  李元方   

  1. 中山大学肿瘤防治中心胃外科 华南恶性肿瘤防治全国重点实验室,广州510060

  • 通讯作者: 李元方,Email:liyuanf@sysucc.org.cn
  • 基金资助:

    广东省自然科学基金(2022A1515012458)

Abstract:

The incidence of esophagogastric junction adenocarcinoma is still high in China. In recent years, surgical treatment combined with chemotherapy, radiotherapy, immunotherapy, and targeted therapy has gradually improved the prognosis of patients with gastric cancer, but there are still many controversies in the perioperative treatment. This study summarized the research progress related to perioperative treatment for esophagogastric junction adenocarcinoma, including preoperative neoadjuvant therapy, postoperative adjuvant therapy, perioperative radiotherapy, and immunotherapy, so as to clarify the current research direction.

Key words:

Esophagogastric junction adenocarcinoma, Perioperative treatment, Neoadjuvant therapy, Adjuvant therapy, Chemotherapy,  , Radiotherapy, Immunotherapy, Progress

摘要:

食管胃结合部腺癌在我国的发病率仍居高不下。近年来,以手术治疗为主,联合化疗、放疗、免疫治疗、靶向治疗等综合治疗模式逐步改善了患者的预后,但围手术期治疗模式还存在不少争议。本文总结了食管胃结合部腺癌围手术期治疗相关研究进展,从术前新辅助治疗、术后辅助治疗、围手术期放疗及免疫治疗等方面进行综述,以明晰目前研究方向。

关键词:

食管胃结合部腺癌, 围手术期治疗, 新辅助治疗, 辅助治疗, 化疗, 放疗, 免疫治疗, 进展