International Medicine and Health Guidance News ›› 2023, Vol. 29 ›› Issue (18): 2517-2521.DOI: 10.3760/cma.j.issn.1007-1245.2023.18.001

• New Medical Advances •     Next Articles

Research progress on new immunosuppressive agents in treatment of idiopathic membranous nephropathy

Yang Jia1, Xi Zhefan1, Zou Haozhen1, Xu Qiang2, Dong Hua1   

  1. 1 Department of Nephrology, Binzhou Medical University Hospital, Binzhou 256603, China; 2 Department of Critical Care Medicine, Binzhou People's Hospital, Binzhou 256601, China

  • Received:2023-04-01 Online:2023-09-15 Published:2023-09-21
  • Contact: Dong Hua, Email: donghua197704@sina.com

新型免疫抑制剂在特发性膜性肾病治疗中的研究进展

杨佳1  席哲帆1  邹皓珍1  徐强2  董华1   

  1. 1滨州医学院附属医院肾内科,滨州 256603;2滨州市人民医院重症医学科,滨州  256601

  • 通讯作者: 董华,Email:donghua197704@sina.com

Abstract:

Idiopathic membranous nephropathy is the most common cause of nephrotic syndrome in adults. Although conventional immunosuppressive drugs can improve the remission rate, there are serious adverse effects and some patients can progress to end-stage renal disease within a few years. This article mainly introduces the progress on new immunosuppressive agents in the treatment of idiopathic membranous nephropathy.

Key words:

Idiopathic membranous nephropathy, New immunosuppressive agents, Rituximab, Progress

摘要:

特发性膜性肾病是成人肾病综合征最常见的原因。传统的免疫抑制剂虽能提高缓解率,但存在严重不良反应,部分患者在数年内可进展为终末期肾病。本文主要介绍新型免疫抑制剂在特发性膜性肾病治疗中的进展。

关键词:

特发性膜性肾病, 新型免疫抑制剂, 利妥昔单抗, 进展