Abstract:

 Objective　To evaluate the efficacy of warming yang and transforming qi in the treatment of urinary retention after radical resection of cervical cancer by meta analysis system. Methods　Chinese National Knowledge Infrastructure (CNKI), Wanfang data Medical Information system, VIP Information Resource system (VIP), Chinese Biomedical Literature Database, PubMed, Embase, Cochrane Library, and Web of Science were searched from the date of establishment of the databases to January 31, 2023. Cochrane bias risk assessment tool was used to evaluate the quality of included literatures, and RevMan 5.4 software was used for meta analysis. Results　A total of 352 patients were included in 5 literatures. The results of meta analysis showed that the adjuvant therapy of warming yang and transforming qi could reduce the incidence of urinary retention after radical resection of cervical cancer (OR=0.13, 95%CI [0.04, 0.40], Z=3.55, P=0.000 4) and bladder residual urine (WMD=-54.71, 95%CI [-56.10, -53.32], Z=77.05, P<0.000 01), and improve the total effective rate of treatment (OR=1.19, 95%CI [1.05, 1.34], Z=2.77, P=0.006). Conclusion　Compared with routine treatment of western medicine alone, the adjuvant therapy of warming yang and transforming qi may have potential advantages in improving urinary retention after radical resection of cervical cancer, which needs to be verified by more high-quality studies.

Key words:

Cervical cancer, Postoperative urinary retention, Warming yang and transforming qi, Meta analysis

摘要：

目的　通过meta分析系统评价温阳化气法治疗宫颈癌根治术后尿潴留的疗效。方法　选择中国知网、中国生物医学文献数据库、维普中文科技期刊全文数据库、万方医药期刊数据库以及PubMed、Embase、Cochrane Library、Web of Science中相关文献，检索年限从建库至2023年1月31日，采用Cochrane偏倚风险评估工具评价纳入文献质量，用RevMan 5.4软件进行meta分析。结果　纳入文献5篇，共352例患者，meta分析结果显示温阳化气法辅助治疗可以降低宫颈癌根治术后尿潴留发生率（OR=0.13，95%CI 0.04～0.40，Z=3.55，P=0.000 4），减少膀胱残余尿量（WMD=-54.71，95%CI -56.10～-53.32，Z=77.05，P<0.000 01），提高治疗的总有效率（OR=1.19，95%CI 1.05～1.34，Z=2.77，P=0.006）。结论　对比单用西医常规治疗，温阳化气法辅助治疗在改善宫颈癌根治术后尿潴留方面，可能具有潜在疗效优势，待更多高质量研究验证。

关键词:

宫颈癌, 术后尿潴留, 温阳化气, meta分析