Abstract: Objective　To excavate the relevant data of patented traditional Chinese medicine for treating chronic gastritis, and provide new ideas and directions for clinical drug use and scientific research. Methods　The patent information related to chronic gastritis and traditional Chinese medicine was searched from State Intellectual Property Office, China National Knowledge Infrastructure (CNKI), and Wanfang Data. R language was used to extract the names of traditional Chinese medicine mentioned in the patents. Python and Excel were used to analyze the patent distribution, Chinese medicine word frequency statistics, and drug combination, so as to understand the use frequency of traditional Chinese medicine and the combination for chronic gastritis and generate word cloud graphs, drug efficacy classification maps, and drug meridian graphs. Vosviewer was used to analyze the cluster of traditional Chinese medicine for understanding the typical Chinese medicine and its rules. Results　A total of 1 639 pieces of valid patent information were included after screening, involving 421 prescriptions of Chinese medicine; and the top 40 of frequency were summarized. According to the effect classification, Buxu and Qi-circulating drugs were the main drugs; spleen and stomach meridians were the main drug meridians, with assistant effect on liver and lung meridians. Drug cluster analysis attributed all traditional Chinese medicine to four categories: tonifying middle-Jiao and Qi, dredging liver to regulate qi, reinforcing spleen to promote digestion, and phlegm-resolving and Qi-circulating. Conclusion　Chronic gastritis closely relates to spleen, stomach, liver, and lung. The Buxu and Qi-circulating drug is a good choice for it, indicating the rules and characteristics of traditional Chinese medicine in the patent databases and provides new ideas and references for clinical and scientific research.

Key words: Chronic gastritis, Patent, Chinese medicine, Data analysis

摘要： 目的　挖掘专利中中医药治疗慢性胃炎的相关数据信息，为临床用药和科研提供新的思路和方向。方法　通过检索国家知识产权局、中国知网、万方数据库，检索慢性胃炎与中医药相关的专利信息，利用R语言提取专利中提及的中药名称，利用Python和Excel针对专利分布及其涉及的中药进行词频统计和药物组合情况分析，了解治疗慢性胃炎中药使用频次及其组合情况，生成词云图、药物功效分类图、药物归经图，利用Vosviewer进行中药的聚类分析，了解每一类中的典型中药及其规律。结果　经过筛选纳入有效专利信息1 639条，共涉及421味中药并将频次出现前40味进行归纳总结；按照功效分类主要以补虚、行气药为主；药物归经以脾经、胃经为主，兼顾肝经、肺经。药物聚类分析将所有中药主要归结为补中益气类、疏肝理气类、健脾消食类、化痰行气类4个大类。结论　慢性胃炎与脾、胃、肝、肺等脏腑关系最为密切，多选用具有补虚、行气功效的药物，充分揭示了专利数据库中中医药对慢性胃炎的用药规律及组方特点，为临床及科研提供新的思路及参考。

关键词: 慢性胃炎, 专利, 中药, 计量分析