Abstract: Objective　To observe, evaluate, and analyze the clinical effect of Uphis products on wound repair after CO₂ fractional laser surgery. Methods　A total of 60 patients who received CO₂ fractional laser treatment from July 2018 to February 2019 in Department of Dermatology, Guangdong Provincial Hospital of Traditional Chinese Medicine were selected, and were divided into an observation group and a control group according to the nursing methods after surgery, with 30 cases in each group. The observation group had 13 males and 17 females who were (23.43±2.12) years old, and used Uphis multi-effect repairing liquid to spray their faces and revitalizing and soothing repairing masks after surgery every morning and evening for 20 minutes each time. The control group had 20 males and 10 females who were (23.63±3.54) years old, and sprayed their faces with normal saline and used normal saline masks after surgery every morning and evening for 20 minutes each time. Both groups were continuously treated for 7 days, and the patients' facial restoration was tracked for nearly 7 days. The measurement data were expressed as (x±s). The results of pain and itch index, the days for scars starting to remove, the total days of scar removal, and the days of missing work in the two groups were tested by t test. The clinical efficacies and the incidences of adverse reactions in the two groups were tested by chi square test. Results　After the treatment, there was no statistical difference in the pain rating score between the observation group and the control group [(2.46±1.41) vs. (2.70±2.83), (t=0.401 8, P=0.534 0)]. The observation group had itching. The itch index score of the observation group was significantly lower than that of the control group [(0.36±0.70) vs. (1.73±0.62)], with a statistical difference (t=5.179 3, P=0.001 3). The days for scars starting to remove, the total days of scar removal, and the days of missing work in the observation group were significantly lower than those in the control group, with statistical differences (t=4.281 7, 5.067 3, and 4.073 5; all P<0.05). The nursing satisfaction of the observation group was significantly higher than that of the control group [96.67% (29/30) vs. 76.67% (29/30)], with a statistical difference (χ²=5.192 3, P=0.001 8). Conclusion　Uphis products can effectively shorten the duration of facial erythema after CO₂ laser surgery and the times of postoperative wound scab formation and removal, relieve itching, reduce the incidence of pigmentation, promote wound repair, and improve the treatment efficacy.

Key words: CO₂ fractional laser, Ice compress, Uphis, Wound repair, Postoperative care

摘要： 目的　观察评价分析优斐斯产品对CO₂（二氧化碳）点阵激光术后创面修复的临床效果。方法　选择2018年7月至2019年2月广东省中医院皮肤科门诊使用CO₂点阵激光治疗的60例患者，将患者按激光术后不同护理方法分为观察组和对照组，观察组30例（男13例，女17例），年龄（23.43±2.12）岁，激光后给予优斐斯多效修护液喷脸联合活肤舒缓修护面膜贴敷，每次贴20 min，每天早晚各1次；对照组30例（男20例，女10例），年龄（23.63±3.54）岁，激光后立即予生理盐水喷脸联合生理盐水冷敷贴贴敷，每次贴20 min，每天早晚各1次。两组均连续使用7 d，追踪患者近7 d的面部修复情况。计量资料以均数±标准差（x±s）表示，两组患者疼痛及瘙痒指数结果、开始脱痂天数、总脱痂天数及误工天数结果采用t检验，两组患者临床疗效及不良反应发生率采用χ²检验。结果　观察组患者治疗后疼痛分级评分为（2.46±1.41）分，与对照组（2.70±2.83）分比较，差异无统计学意义（t=0.401 8，P=0.534 0）；观察组瘙痒指数评分为（0.36±0.70）分，明显低于对照组（1.73±0.62）分，差异有统计学意义（t=5.179 3，P=0.001 3）；观察组治疗后开始脱痂天数、总脱痂天数及误工天数显著低于对照组，差异均有统计学意义（t=4.281 7、5.067 3、4.073 5，均P<0.05）；观察组护理满意度96.67%（29/30）高于对照组76.67%（23/30），差异有统计学意义（χ²=5.192 3，P=0.001 8）。结论　优斐斯产品在CO₂激光术后能有效缩短面部红斑持续时间、术后创面结痂及脱痂时间，减轻瘙痒感，降低色沉发生率，促进创面修复，提高治疗的有效率。

关键词: CO₂点阵激光, 冰敷, 优斐斯, 创面修复, 术后护理