Application of IL-6 and SAA in the early diagnosis of neonatal sepsis

doi:10.3760/cma.j.issn.1007-1245.2021.06.016

Abstract

Abstract: Neonatal sepsis has an acute onset and rapid progression, and is the main cause of neonatal death. Due to the lack of specific manifestations, the cultivation of pathogenic bacteria takes long time, it is often easily missed and misdiagnosed, delaying the early diagnosis and treatment of children. Inflammatory markers such as peripheral white blood cell count, C-reactive protein, and procalcitonin have been widely used in clinical practice. This article mainly reviews the research of interleukin-6 and serum amyloid A in the early diagnosis of neonatal sepsis.

Key words: Neonatal sepsis, Interleukin-6, Serum amyloid A

摘要： 新生儿败血症起病急,病情进展快,是新生儿死亡的主要原因。由于无特异性表现,病原菌培养耗时长,常易被漏诊和误诊,耽误患儿的早期诊断和治疗,外周血白细胞计数、C-反应蛋白及降钙素原等炎性标志物在临床上早已应用广泛。本文主要对白细胞介素-6及血清淀粉样蛋白A在新生儿败血症的早期诊断中的研究进行综述。

关键词: 新生儿败血症, 白细胞介素-6, 血清淀粉样蛋白

Yang Xiaojuan, Li Xiaodong. Application of IL-6 and SAA in the early diagnosis of neonatal sepsis[J]. International Medicine and Health Guidance News, 2021, 27(6): 848-851.

杨小娟, 李晓东. IL-6及SAA在新生儿败血症早期诊断中的应用[J]. 国际医药卫生导报, 2021, 27(6): 848-851.

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