Abstract:

The nursing experience of three children with grade Ⅳ graft-versus-host disease after hematopoietic stem cell transplantation was summarized. The nursing points were as below: making a nursing plan for the medical team and providing full process management; paying attention to environmental management and ensuring protective isolation; taking good care of the skin wound, fixing the central venous catheter, and providing nutritional support and psychological care. After effective treatment and careful care, the affected areas of the children's skin lesions basically healed.

Key words:

Hematopoietic stem cell transplantation, Grade Ⅳ, Graft-versus-host disease, Nursing, Children

摘要：

总结3例造血干细胞移植术后患儿发生Ⅳ度皮肤移植物抗宿主病（GVHD）的护理经验。其护理要点包括：医护团队建立护理计划，提供全程管理；注重环境管理，做好保护性隔离；做好皮肤创面的护理、中心静脉导管的固定，提供营养支持和心理护理。经过有效的治疗和精心护理，患儿皮损部位基本愈合。

关键词:

造血干细胞移植, Ⅳ度, 移植物抗宿主病, 护理, 患儿