Advances in the relationships between small heat shock proteins and tumor apoptosis

doi:10.3760/cma.j.issn.1007-1245.2023.03.001

Abstract

Abstract:

Small heat shock proteins (sHSPs) are a large group of many heat shock proteins (HSPs), including HSPB1, HSPB5, HSPB6, and HSPB8. Recent studies have shown that they play key roles in many signaling pathways that have many connections with tumorigenesis, anti-radiation, and apoptosis inhibition, especially in tumor apoptosis. In this paper, the effects of sHSPs on tumor apoptosis pathways are reviewed.

Key words:

Small heat shock proteins, , Tumor, , Apoptosis, , Heat inducing

摘要：

小分子热休克蛋白（small heat shock proteins，sHSPs）是众多热休克蛋白（heat shock proteins，HSPs）中的一大类，包括HSPB1、HSPB5、HSPB6、HSPB8等。近来研究表明，它们在许多信号通路扮演关键角色，这些信号通路与肿瘤的发生、抗放疗和凋亡的抑制有着许多联系，尤其是在肿瘤凋亡方面。本文对sHSPs在肿瘤凋亡途径方面予以综述。

关键词:

小分子热休克蛋白, 肿瘤, 凋亡, 热诱导

Wang Yimin, Li Qinghua.

Advances in the relationships between small heat shock proteins and tumor apoptosis [J]. International Medicine and Health Guidance News, 2023, 29(3): 297-301.

王怡民李清华.

小分子热休克蛋白与肿瘤凋亡关系的研究进展 [J]. 国际医药卫生导报, 2023, 29(3): 297-301.

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