International Medicine and Health Guidance News ›› 2022, Vol. 28 ›› Issue (21): 3106-3108.DOI: 10.3760/cma.j.issn.1007-1245.2022.21.033

• Summary • Previous Articles    

Clinical progress of glucagon-like peptide 1 receptor agonist in treatment of diabetic nephropathy

Guo Chaohua, He Qing, Xing Yuanyuan   

  1. Department of Endocrinology and Nephrology, Tianjin Peking University Offshore Oil Hospital, Tianjin 300452, China
  • Received:2022-08-09 Online:2022-11-01 Published:2022-11-17
  • Contact: Guo Chaohua, Email: zj81vw@163.com

胰高血糖素样肽1受体激动剂治疗糖尿病肾病的临床研究进展

郭超花  何晴  邢媛媛   

  1. 天津北大海洋石油医院内分泌肾科 300452
  • 通讯作者: 郭超花,Email:zj81vw@163.com

Abstract: Diabetes affects global health problems. Diabetes nephropathy is one of its common microvascular complications, and also one of the major diseases leading to nephropathy (ESRD). At present, glucagon-like peptide 1 receptor agonist (GLP-1RA), one of the hypoglycemic drugs, has become the main treatment for diabetes patients, and can effectively reduce blood glucose. More and more studies have shown that GLP-1RA can protect the kidney no matter what the hypoglycemic effect is. This article analyzes the clinical research progress of GLP-1RA in the treatment of diabetes by analyzing clinical data.

Key words: Glucagon-like peptide 1 receptor, Diabetic nephropathy, Agonist

摘要: 糖尿病影响全球健康问题,糖尿病肾病是其通常的微血管并发症之一,而且还是导致肾病的主要疾病之一(ESRD)。目前降血糖药物中的胰高血糖素-1受体激动剂(glucagon-like peptide 1 receptor agonist,GLP-1RA),成为治疗糖尿病患者的主要方法,能有效降低血糖。越来越多的研究表明,无论低血糖效应如何,GLP-1RA都有保护肾脏的作用。本文通过分析临床资料,分析GLP-1RA应用于治疗糖尿病的临床研究进展。

关键词: 胰高血糖素样肽1受体, 糖尿病肾病, 激动剂