Abstract: Objective　To investigate the psychological distress of patients with failure of the first in vitro embryo transfer and their spouses and to analyze the influencing factors. Methods　This study was a retrospective study. From September 2020 to September 2021, 160 couples who failed to undergo the first in vitro embryo transfer in 73rd Group Army Hospital of Chinese People's Liberation Army were selected as the research objects. They were divided into two groups according to the patients and their spouses. The General Data Questionnaire, Simple Psychological Status Questionnaire, Mental Resilience Scale, Simple Coping Style Scale, and Comprehending Social Support Scale were used to investigate the objects, and the results were compared. t test was used for statistical analysis. The correlation of psychological distress with the scores of psychological resilience, simple coping style, and understanding of social support was analyzed by Pearson correlation analysis. The influencing factors of psychological distress were analyzed by multiple linear regression. Results　The psychological distress score was (22.48±6.81) in the patients, and was (19.57±6.38) in their spouses (P<0.05). Multiple linear regression analysis showed that age, infertility time, infertility type, and negative coping style were all risk factors for psychological distress of the patients and their spouses, while psychological resilience and social support were protective factors (all P<0.05). Conclusions　Psychological distress of patients with failure of first in vitro embryo transfer and their spouse is common, and the patients' psychological distress degree is higher than their spouses'. Age, infertility time, infertility type, and negative coping style are all risk factors for psychological distress, while psychological resilience and social support are protective factors. Nursing staff can formulate targeted nursing interventions to help them effectively alleviate psychological distress.

Key words: Failure of in vitro embryo transfer, Patients and their spouses, Psychological distress

摘要： 目的　探讨首次体外胚胎移植失败患者及其配偶心理困扰现状，并分析其影响因素。方法　本研究为回顾性研究，选取2020年9月至2021年9月在中国人民解放军陆军第七十三集团军医院进行首次体外胚胎移植失败160对夫妻为研究对象，其中女性年龄20～42（30.04±5.27）岁，男性年龄20～45（32.58±5.13）岁。按患者及配偶分成两组，采用一般资料调查表、简易心理状况调查表、心理弹性量表、简易应对方式量表、领悟社会支持量表进行调查比较。采用t检验进行统计分析，Pearson相关分析心理困扰得分与心理弹性、简易应对方式、领悟社会支持得分间的相关性，并应用多元线性回归分析对其心理困扰的影响因素。结果　患者心理困扰得分为（22.48±6.81）分，配偶心理困扰得分为（19.57±6.38）分（P<0.05）。多元线性回归分析表示，年龄、不孕时间、不孕类型、消极应付方式均是共同影响患者及其配偶心理困扰的危险因素，而心理弹性、社会支持度是心理困扰的保护因素（均P<0.05）。结论　首次体外胚胎移植失败患者及其配偶普遍存在心理困扰现状，且首次体外胚胎移植失败患者的心理困扰程度高于配偶；年龄、不孕时间、不孕类型与消极应付方式均是心理困扰的危险因素，心理弹性、社会支持度是心理困扰的保护因素。护理人员可制定针对性的护理干预，帮助该人群有效缓解心理困扰。

关键词: 体外胚胎移植失败, 患者及其配偶, 心理困扰