Theoretical basis and overview of Banxia Xiexin decoction in treatment
of digestive diseases

doi:10.3760/cma.j.issn.1007-1245.2022.17.009

International Medicine and Health Guidance News ›› 2022, Vol. 28 ›› Issue (17): 2410-2413.DOI: 10.3760/cma.j.issn.1007-1245.2022.17.009

• Scientific Research • Previous Articles Next Articles

Theoretical basis and overview of Banxia Xiexin decoction in treatment of digestive diseases

He Wenguang, Liu Xiaoli, Xie Yicheng

The Fourth Affiliated Hospital of Guangzhou Medical University, Guangzhou 511300, China

Received:2022-06-21 Online:2022-09-01 Published:2022-10-11
Contact: Xie Yicheng, Email: wenlijia121@163.com
Supported by:
Scientific Research Project of Guangdong Provincial Administration of Traditional Chinese Medicine (20190411143859)

半夏泻心汤治疗消化性疾病的理论基础及概述

何文广刘小梨谢意程

广州医科大学附属第四医院普外科，广州　511300

通讯作者: 谢意程，Email：wenlijia121@163.com
基金资助:
广东省中医药局科研项目（20190411143859）

Abstract

Abstract: A large number of studies have shown that Banxia Xiexin decoction can effectively treat and improve digestive diseases. This article reviews the application of Banxia Xiexin decoction and summarizes its clinical advances and mechanism, so as to provide necessary references and guidance for clinical practice and evidences for further research.

Key words: Banxia Xiexin decoction, Digestive diseases, Theoretical basis, Overview

摘要： 大量研究表明，半夏泻心汤可有效治疗和改善消化系统疾病。本文就半夏泻心汤在该领域的临床进展和机制作一综述，旨在为临床提供必要的参考和指导，以及未来研究提供证据基础。

关键词: 半夏泻心汤, 消化性疾病, 理论基础, 概述

He Wenguang, Liu Xiaoli, Xie Yicheng. Theoretical basis and overview of Banxia Xiexin decoction in treatment of digestive diseases [J]. International Medicine and Health Guidance News, 2022, 28(17): 2410-2413.

何文广刘小梨谢意程. 半夏泻心汤治疗消化性疾病的理论基础及概述[J]. 国际医药卫生导报, 2022, 28(17): 2410-2413.

References

[1] 张仲景.伤寒杂病论(桂林古本)[M].2版.南宁:广西人民出版社,1980: 82, 84.
[2] 李付平,葛玉琴,宗义君,等. 半夏泻心汤的古代文献考证[J]. 中国实验方剂学杂志,2020,26(22):164-171. DOI:10.13422/j.cnki.syfjx.20202085.
[3] 国家中医药管理局.关于发布«古代经典名方目录(第一批)»的通知[EB/OL]. (2018-04-16/2019-05-20)[2022-06-21]. http://kjs.satcm.gov.cn/zhengcewenjian/2018-04-16/7017.Html.
[4] 李斌斌,高音来,康毅,等. 半夏泻心汤研究进展[J]. 中医学报, 2019, 34(12):2549-2554. DOI:10.16368/j.issn.1674-8999.2019.12.586.
[5] 范玉霞,刘晓春,李振海. 半夏泻心汤联合三联疗法治疗消化性溃疡的临床效果[J]. 中国当代医药,2019,26(29):164-166,170. DOI:10.3969/j.issn.1674-4721.2019.29.048.
[6] 罗红涛. 半夏泻心汤联合常规西药治疗慢性胃溃疡临床观察[J]. 新中医,2018,50(6):96-98. DOI:10.13457/j.cnki.jncm.2018.06.025.
[7] 杨静波,赵长普,李一豪. 半夏泻心汤加减治疗胃溃疡临床观察[J]. 中国中医基础医学杂志,2018,24(3):364-366.
[8] 邵明水. 半夏泻心汤加味治疗胃炎60例[J]. 中国民族民间医药,2010,19(14):161-161. DOI:10.3969/j.issn.1007-8517.2010.14.158.
[9] 吴拓生. 半夏泻心汤联合西药治疗慢性萎缩性胃炎的效果和安全性[J]. 中外医学研究,2018,16(35):33-35. DOI:10.14033/j.cnki.cfmr.2018.35.015.
[10] Cao Y, Zheng Y, Niu J, et al. Efficacy of Banxia Xiexin decoction for chronic atrophic gastritis: a systematic review and meta-analysis [J]. PLoS One, 2020, 15(10): e0241202. DOI: 10.1371/journal.pone.0241202.
[11] 彭红琼. 半夏泻心汤加减治疗溃疡性结肠炎64例[J]. 检验医学与临床,2010,7(13):1377-1378. DOI:10.3969/j.issn.1672-9455.2010.13.054.
[12] 黄亮. 半夏泻心汤加减治疗溃疡性结肠炎临床观察[J]. 光明中医,2019,34(2):199-201. DOI:10.3969/j.issn.1003- 8914.2019.02.012.
[13] Liu X, Wang S, Li J, et al. Regulatory effect of traditional Chinese medicines on signaling pathways of process from chronic atrophic gastritis to gastric cancer[J]. 中草药(英文版), 2022, 14(1):5-19.
[14] 张玲,徐鹏陶. 半夏泻心汤治疗慢性萎缩性胃炎临床效果分析[J]. 中国继续医学教育,2018,10(9):122-124. DOI:10.3969/j.issn.1674-9308.2018.09.064.
[15] 童荣生,肖开春,李晋奇,等. 半夏泻心汤调节胃肠动力的物质基础研究[J]. 中国实验方剂学杂志,2015,21(3):160-163. DOI:10.13422/j.cnki.syfjx.2015030160.
[16] 尹抗抗,曹蓉,唐标,等. 半夏泻心汤对幽门螺杆菌感染胃炎小鼠胃内微生物及酶的影响[J]. 世界华人消化杂志,2014(21):3067-3071.
[17] 王菁,杨冰,李丽,等. 半夏泻心汤联合胃复春对慢性萎缩性胃炎患者血清表皮生长因子及血清胃蛋白酶原、胃泌素表达影响[J]. 辽宁中医药大学学报,2019,21(7):154-157. DOI:10.13194/j.issn.1673-842x.2019.07.041.
[18] Bai Y, Chen Y, Chen Y, et al. Efficacy of Banxia Xiexin decoction in a rat model of chronic atrophic gastritis[J]. 中医杂志(英文版), 2019, 39(6):867-874.
[19] 石铖,王茜,刘宇,等. 基于Keap1/Nrf2/ARE信号通路探讨半夏泻心汤对慢性萎缩性胃炎大鼠的影响及作用机制[J]. 中国实验方剂学杂志,2021,27(20):31-37. DOI:10.13422/j.cnki.syfjx.20211901.
[20] 吴新辉,周烨鑫,成克用,等. 半夏泻心汤全方及其不同组分对幽门螺杆菌感染小鼠的作用及机制分析[J]. 中医药信息,2018,35(3):17-20. DOI:10.19656/j.cnki.1002-2406. 180075.
[21] 徐凤,毛艺纯,周淑芬,等. 半夏泻心汤对溃疡性结肠炎小鼠肠道黏膜屏障功能保护作用及ZO-1和Occludin表达的影响[J]. 中国中医基础医学杂志,2019,25(1):44-47,51.
[22] 呼永华,薛文翰. 半夏泻心汤对减轻化疗胃肠道不良反应的疗效[J]. 甘肃医药,2013,32(12):919-920.
[23] 龚仪棠. 半夏泻心汤辅助治疗化疗药物所致胃肠道反应临床疗效[J]. 中国中医急症,2017,26(5):897-899. DOI:10.3969/j.issn.1004-745X.2017.05.046.
[24] Li K, Liu R, Xu G, et al. Effect of a modified Banxia Xiexin decoction plus chemotherapy on stage Ⅲ colon cancer[J]. 中医杂志(英文版), 2019, 39(2):251-257.
[25] Yan S, Yue Y, Wang J, et al. Banxia Xiexin decoction, a traditional Chinese medicine, alleviates colon cancer in nude mice [J]. Ann Transl Med, 2019, 7(16): 375. DOI: 10.21037/atm.2019.07.26.
[26] 罗玉婷,林龙飞,刘宇灵,等. 基于网络药理学及分子对接技术探讨半夏泻心汤治疗结肠癌潜在分子机制[J]. 中国中药杂志,2020,45(23):5753-5761. DOI:10.19540/j.cnki.cjcmm.20201026.401.
[27] 崔国宁,刘喜平,李沛清,等. 半夏泻心汤调控Shh信号通路对BMSCs外泌体诱导的人胃癌细胞BGC-823增殖的影响[J]. 中国中医药信息杂志,2021,28(8):77-82. DOI:10.19879/j.cnki.1005-5304.202011548.
[28] Feng X, Xue F, He G, et al. Banxia Xiexin Decoction inhibits the expression of PD-L1 through multi-target and multi-pathway regulation of major oncogenes in gastric cancer [J]. Onco Targets Ther, 2021, 14:3297-3307. DOI: 10.2147/OTT.S288442.

Theoretical basis and overview of Banxia Xiexin decoction in treatment of digestive diseases

半夏泻心汤治疗消化性疾病的理论基础及概述

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