Analysis of risk factors of cervical insufficiency in patients with polycystic
ovary syndrome and late abortion undergoing pregnancy-assisted therapy

doi:10.3760/cma.j.issn.1007-1245.2022.08.009

Abstract

Abstract: Objective　To analyze the influencing factors of cervical insufficiency (CI) in patients with polycystic ovary syndrome (PCOS) complicated with late abortion who receive pregnancy-assisted therapy. Methods　A total of 102 patients with PCOS with late abortion receiving pregnancy-assisted therapy were selected from Women & Infants Hospital of Zhengzhou between January 2019 and December 2020. The patients' age was (32.39±6.54) years old, and there were 78 cases of singleton pregnancy and 24 cases of multiple pregnancy. According to whether CI occurred, the patients were divided into a control group (without CI, 88 cases) and an observation group (with CI, 14 cases). The general conditions of the two groups were compared by univariate analysis (independent sample t test and χ² test), multivariate logistic regression analysis was performed on the data with statistically significant differences in the univariate analysis to screen the influencing factors of CI. Results　Multivariate logistic analysis showed that average uterine diameter, pre-pregnancy body mass index (BMI), multiple pregnancy, and preterm birth history were the influencing factors for CI in PCOS patients with late pregnancy-assisted abortion (OR=2.678, 2.918, 2.872, and 3.792; all P<0.05). Conclusions　The average uterine diameter, pre-pregnancy BMI, multiple pregnancy, and preterm birth history are the influencing factors for CI in PCOS patients with late pregnancy-assisted abortion. It is necessary to take corresponding measures according to the above factors to reduce the probability of CI.

Key words: Polycystic ovary syndrome, Late abortion, Cervical insufficiency, Risk factors

摘要： 目的　分析接受辅助生殖助孕多囊卵巢综合征（PCOS）晚期流产患者发生宫颈机能不全（CI）的影响因素。方法　选取2019年1月至2020年12月郑州市妇幼保健院收治的辅助生殖助孕PCOS晚期流产患者102例，患者年龄（32.39±6.54）岁，单胎妊娠78例、多胎妊娠24例。按是否出现CI分为对照组（未出现CI）88例及观察组（出现CI）14例，比较两组患者一般情况，采用单因素分析（独立样本t检验、χ²检验），差异有统计学意义的数据进行多因素logistic回归分析，筛查CI的影响因素。结果　多因素logistic分析显示子宫平均径线、孕前体质量指数（BMI）、是否多胎及早产史为助孕晚期流产的PCOS患者出现CI的影响因素（OR=2.678、2.918、2.872、3.792，均P<0.05）。结论　子宫平均径线、孕前BMI、是否多胎及早产史为助孕晚期流产的PCOS患者出现CI的影响因素，需针对以上因素采取相应的措施以降低出现CI的概率。

关键词: 多囊卵巢综合征, 晚期流产, 宫颈机能不全, 危险因素

Liu Caixia, Zhou Xinhua, Guo Baozhi, Guo Huanhuan. Analysis of risk factors of cervical insufficiency in patients with polycystic ovary syndrome and late abortion undergoing pregnancy-assisted therapy [J]. International Medicine and Health Guidance News, 2022, 28(8): 1077-1080.

刘彩霞, 周新华, 郭宝芝, 郭欢欢. 辅助生殖助孕的多囊卵巢综合征晚期流产患者发生宫颈机能不全的危险因素分析[J]. 国际医药卫生导报, 2022, 28(8): 1077-1080.

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Analysis of risk factors of cervical insufficiency in patients with polycystic ovary syndrome and late abortion undergoing pregnancy-assisted therapy

辅助生殖助孕的多囊卵巢综合征晚期流产患者发生宫颈机能不全的危险因素分析

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