Abstract:

Objective　To investigate the clinical efficacy of multidisciplinary collaborative care models in patients with gestational hypertension. Methodology　A randomized controlled trial was conducted, in which 200 patients diagnosed with gestational hypertension and preeclampsia through comprehensive clinical examinations at Xi'an People's Hospital (Xi'an Fourth Hospital) between April 2023 and May 2024 were selected and randomly assigned to either the control group (100 cases) or the experimental group (100 cases) using a random number table method. The control group comprised patients with a mean age of (29.28±3.67) years and gestational age of (26.18±1.28) weeks, who received standard care protocols.The experimental group comprised patients with a mean age of (29.53±3.46) years and gestational age of (25.97±1.43) weeks, who received multidisciplinary collaborative nursing intervention.Compare the blood pressure (diastolic blood pressure, systolic blood pressure, mean arterial pressure), vascular endothelial function [endothelin-1 (ET-1), nitric oxide (NO)] levels, and maternal-neonatal outcomes between the two groups of patients before and after the intervention.Statistical analysis was conducted using t-tests and χ² tests. Results　After the intervention, the experimental group exhibited the following parameters: diastolic blood pressure (81.23±7.69 mmHg; 1 mmHg=0.133 kPa), systolic blood pressure (116.25±13.54) mmHg, mean arterial pressure (75.68±5.52) mmHg, ET-1 level (23.49±3.36 μmol/L), and NO level (56.39±8.72) ng/L. The control group showed corresponding values of 87.37±7.37 mmHg, (126.48±16.48 mmHg, (79.37±5.76) mmHg, (20.43±3.23) μmol/L, and (70.56±9.38) ng/L, respectively. All intergroup differences were statistically significant (all P<0.05).The incidence of adverse pregnancy outcomes in the experimental group [16.00% (16/100)] and neonatal adverse outcomes [3.00% (3/100)] were significantly lower than those in the control group [36.00% (36/100) and 13.00% (13/100), respectively], with statistically significant differences between the two groups (all P<0.05). Conclusion　The multidisciplinary collaborative care model demonstrates efficacy in reducing blood pressure levels among pregnant women with hypertension, promoting the amelioration of vascular endothelial function, and mitigating the incidence of adverse pregnancy outcomes as well as neonatal complications.

Key words:

Gestational hypertension, Multidisciplinary collaboration, Blood pressure, Delivery outcomes

摘要：

目的　探讨妊娠高血压患者中运用多学科协同护理模式的临床效果。方法　采用随机对照试验，选取2023年4月至2024年5月在西安市人民医院（西安市第四医院）经临床综合检查确诊为子痫前期的200例妊娠期高血压患者，采取随机数字表法分为对照组（100例）和试验组（100例）。对照组患者年龄（29.28±3.67）岁，孕周（26.18±1.28）周，采用常规护理方案；试验组患者年龄（29.53±3.46）岁，孕周（25.97±1.43）周，采用多学科协同护理模式。比较两组患者干预前后的血压（舒张压、收缩压、平均动脉压）、血管内皮功能［内皮素-1（ET-I）、一氧化氮（NO）］水平以及母婴结局。采用t检验、χ²检验进行统计分析。结果　干预后，试验组舒张压、收缩压、平均动脉压、ET-1与NO水平分别为（81.23±7.69）mmHg（1 mmHg=0.133 kPa）、（116.25±13.54）mmHg、（75.68±5.52）mmHg、（23.49±3.36）μmol/L、（56.39±8.72）ng/L，对照组分别为（87.37±7.37）mmHg、（126.48±16.48）mmHg、（79.37±5.76）mmHg、（20.43±3.23）μmol/L、（70.56±9.38）ng/L，两组比较差异均有统计学意义（P<0.05）。试验组不良妊娠结局发生率［16.00%（16/100）］、新生儿不良结局发生率［3.00%（3/100）］均低于对照组［36.00%（36/100）、13.00%（13/100）］，两组比较差异均有统计学意义（P<0.05）。结论　多学科协同护理模式有利于降低妊娠高血压患者血压水平，促进血管内皮功能的改善，减少不良妊娠结局及新生儿结局发生。

关键词:

妊娠高血压, 多学科协同, 血压, 分娩结局