Analysis of 20 cases of Kawasaki disease complicated with coronary artery lesions undergoing percutaneous coronary angiography

doi:10.3760/cma.j.cn441417-20240903-09008

International Medicine and Health Guidance News ›› 2025, Vol. 31 ›› Issue (9): 1445-1450.DOI: 10.3760/cma.j.cn441417-20240903-09008

• Special Topic on Kawasaki Disease • Previous Articles Next Articles

Analysis of 20 cases of Kawasaki disease complicated with coronary artery lesions undergoing percutaneous coronary angiography

Lei Xi¹, Wang Tao¹, Xu Xiaoyan¹, Liu Meiqi¹, Wang Juanli¹, Wang Jie², Jiang Congshan², Zhang Yanmin²

¹Cardiovascular Medicine Department, Xi'an Children's Hospital, Xi'an 710000, China; ²Shaanxi Provincial Key Laboratory of Precision Medicine for Children's Diseases, Xi'an Key Laboratory of Child Health and Diseases, Xi'an 710000, China

Received:2024-09-03 Online:2025-05-01 Published:2025-05-20
Contact: Wang Tao, Email: tonywong121@163.com

川崎病合并冠状动脉病变经皮冠状动脉造影20例结果分析

雷茜¹ 王涛¹ 许小艳¹ 刘美琪¹ 王娟莉¹ 王洁² 蒋丛姗² 张艳敏²

¹西安市儿童医院心血管内科，西安 710000；²陕西省儿童疾病精准医学重点实验室西安市儿童健康与疾病重点实验室，西安 710000

通讯作者: 王涛，Email：tonywong121@163.com
基金资助:
陕西省重点研发计划（2024GH-ZDXM-38）

Abstract

摘要：

目的　分析单中心20例川崎病合并冠状动脉病变（CAL）患儿经皮冠状动脉造影（CAG）结果。方法　回顾性总结分析2020年4月至2023年1月在西安市儿童医院住院的20例川崎病合并CAL且行CAG的患儿资料、CAG结果及随访。结果　20例患儿中男16例，女4例，患病年龄3.55（1.96，5.81）岁，诊断冠状动脉扩张或动脉瘤的时间9.50（8.00，12.25）d，CAG检查时间为病程第41.00（28.25，75.75）个月，共发现38支冠状动脉血管受累，平均1.9支/例。发生CAL的部位共54个，其中冠状动脉瘤最常见（34个，63.0%），其次为轻度扩张（15个，27.8%）、完全闭塞伴侧支血管形成（3个，5.6%）、节段性狭窄（2个，3.7%），其中右冠状动脉闭塞伴辫样新生血管形成1例。34个冠状动脉瘤位于右冠状动脉主干最多见（21/34，61.8%），其次为左冠状动脉主干（7/34，20.6%）、左前降支（5/34，14.7%）、左回旋支（1/34，2.9%）；冠状动脉瘤的形态以囊梭型冠状动脉瘤最多见（17/34，50.0%），其次为梭型冠状动脉瘤（12/34，35.3%）、囊型冠状动脉瘤（3/34，8.8%）、管型冠状动脉瘤（2/34，5.9%）。轻度扩张位于左冠状动脉主干（7/15，46.7%）、左前降支（5/15，33.3%）、右冠状动脉（2/15，13.3%）、左回旋支（1/15，6.7%）。2例患儿行冠状动脉搭桥手术，其中1例系左前降支重度狭窄，病程2个月时发生急性心肌梗死，病程7个月时行冠状动脉搭桥术；另1例系左前降支完全闭塞，病程2年余时诊断为缺血性心肌病，遂行冠状动脉搭桥术。所有患儿未发生冠状动脉瘤破裂，无死亡病例。结论　川崎病合并CAL类型以冠状动脉瘤为主，多位于右冠状动脉主干、左冠状动脉主干及左前降支近端；CAG是准确评估川崎病合并CAL的重要手段，对早期评估病变程度及病程中及时准确评估狭窄及闭塞病变有临床指导价值。

关键词:

川崎病, 冠状动脉病变, 经皮冠状动脉造影, 儿童

Lei Xi, Wang Tao, Xu Xiaoyan, Liu Meiqi, Wang Juanli, Wang Jie, Jiang Congshan, Zhang Yanmin.

Analysis of 20 cases of Kawasaki disease complicated with coronary artery lesions undergoing percutaneous coronary angiography [J]. International Medicine and Health Guidance News, 2025, 31(9): 1445-1450.

雷茜王涛许小艳刘美琪王娟莉王洁蒋丛姗张艳敏.

川崎病合并冠状动脉病变经皮冠状动脉造影20例结果分析 [J]. 国际医药卫生导报, 2025, 31(9): 1445-1450.

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Analysis of 20 cases of Kawasaki disease complicated with coronary artery lesions undergoing percutaneous coronary angiography

川崎病合并冠状动脉病变经皮冠状动脉造影20例结果分析

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