关键词: 肝硬化, 舒适护理, 正念减压疗法, 肝功能, 心理状态, 护理满意度

Abstract:

Objective　To investigate the effects of comfortable care combined with mindfulness-based stress reduction therapy on liver function and psychological state in patients with liver cirrhosis. Methods　A retrospective study included 112 patients with liver cirrhosis admitted to Shaanxi Provincial Nuclear Industry 215 Hospital from April 2020 to April 2023 were divided into a control group (55 cases) and an intervention group (57 cases) based on different nursing approaches.There were 28 males and 27 females in the control group; they were (55.21 ± 14.32) years old; the course of disease was (11.21 ± 3.66) years;the body mass index (BMI) was (23.51 ± 3.01) kg/m².There were 29 males and 28 females in the control group; they were (54.27±15.88) years old;the course of disease was (10.47±4.39) years;the BMI was (23.58±3.45) kg/m².The control group received routine nursing interventions, while the intervention group received comfortable care combined with mindfulness-based stress reduction therapy. Both groups received continuous care for 4 weeks. The scores of Self-Rating Anxiety Scale (SAS) and Self-Rating Depression Scale (SDS),the levels of alanine aminotransferase (ALT) and aspartate aminotransferase (AST),SF-36 quality of life scores, treatment compliance scores, and nursing satisfaction were compared between the two groups. Statistical analysis was performed using t tests and χ² tests. Results　After nursing care, the SAS and SDS scores in the intervention group were significantly lower than those in the control group [(23.12 ± 9.58) ponits vs. (32.58 ± 11.69) ponits and (31.52 ± 12.03) ponits vs. (42.36 ± 10.44) ponits, with statistically significant differences (t=4.167 and 6.871, both P<0.05); the levels of ALT and AST in the intervention group were lower than those in the control group [(32.55 ± 13.88) IU/L vs. (58.31 ± 21.06) IU/L and (35.81 ± 12.03) IU/L vs. (59.22 ± 23.69) IU/L] (t=4.874 and 5.171, both P<0.05); the quality of life score in the intervention group was higher than that in the control group [(78.69 ± 11.33) ponits vs. (67.39 ± 12.36) ponits (t=4.165, P=0.003)]. Treatment adherence was also significantly higher in the intervention group compared to the control group (P<0.05). The overall nursing satisfaction in the intervention group was significantly higher than that in the control group [96.5% (55/57) vs. 81.8% (45/55)], with a statistically significant difference (χ² = 5.314, P = 0.009). Finally, the multiple regression analysis showed that patients receiving comfortable care combined with mindfulness-based stress reduction therapy had a significantly lower ALT level (t =-3.88, P=0.001), a lower SAS score (t =-3.78, P=0.001), higher quality of life score (t = 3.95, P=0.001), and higher nursing satisfaction (t = 3.36, P=0.001). The VIF value was 1.15, indicating no serious multicollinearity issues. Conclusion　Comfortable care combined with mindfulness-based stress reduction therapy has a significant effect in reducing negative emotions, promoting liver function recovery, improving quality of life, enhancing treatment adherence, and increasing nursing satisfaction in patients with liver cirrhosis.

Key words: Liver cirrhosis,  , Comfort care,  , Mindfulness-based stress reduction therapy,  , Liver function,  , Psychological State,  , Nursing satisfaction