术后应用封闭式负压创面治疗技术促进胸壁结核伤口愈合

doi:10.3760/cma.j.cn441417-20250220-10024

摘要/Abstract

摘要：

目的　探讨封闭式负压创面治疗技术在胸壁结核患者术后伤口中的应用效果。方法　本研究为随机对照实验设计，选取2022年2月至2024年3月在广州市胸科医院接受手术治疗的胸壁结核患者60例，采用随机数字表法分为观察组和对照组，各30例。对照组年龄（43.19±0.89）岁，男21例，女9例；观察组年龄（45.79±0.15）岁，男22例，女8例。对照组进行常规敷料引流换药，观察组采用封闭式负压创面治疗技术处理术后伤口。对比两组患者术后第7天临床炎症相关指标、并发症发生率、疗效相关时间指标及生活质量评分。两组统计比较采用t检验、χ2检验。结果　治疗后，观察组患者白细胞计数、血沉和C反应蛋白分别为（7.15±1.24）×109/L、（18.24±2.25）mm/h、（38.15±3.03）mg/L，对照组分别为（9.63±1.15）×109/L、（25.07±2.23）mm/h、（46.17±2.89）mg/L；观察组创面红期、创面愈合、敷料维持以及术后住院时间分别为（4.15±1.02、14.79±2.48、8.16±2.07、8.59±2.18）d，对照组分别为（8.39±2.15、27.34±3.36、23.76±3.89、16.54±3.57）d；观察组总并发症发生率为6.67%（2/30），对照组发生率为33.3%（10/30）；观察组一般情况、心理健康和社会功能得分分别为（85.27±3.42、89.35±5.13、91.15±5.93）分，对照组分别为（80.15±3.65、84.20±5.40、86.90±6.10）分；以上指标两组比较，差异均有统计学意义（均P<0.001）。结论　在胸壁结核术后患者中应用封闭式负压创面治疗技术，能降低患者的临床炎症相关指标，缓解身体不适，改善负面情绪，缩短创面愈合时间。

关键词: , 胸壁结核, , , 封闭式负压创面治疗技术, , , 创面, , , 并发症, , , 生活质量

Abstract:

Objective　To investigate the efficacy of postoperative closed negative pressure wound therapy for wound healing in chest wall tuberculosis. Methods　A total of 60 patients with chest wall tuberculosis who underwent surgery at Guangzhou Chest Hospital between February 2022 and March 2024 were selected for the randomized controlled trial, and were divided into a control group and an observation group by the random number table method, with 30 cases in each group. There were 21 males and 9 females in the control group; they were (43.19±0.89) years old. There were 22 males and 8 females in the observation group; they were (45.79±0.15) years old. The control group received conventional dressing drainage and dressing change. The observation group took closed negative pressure wound therapy to treat their postoperative wounds. The clinical inflammation-related indicators, efficacy-related time indicators, and scores of life quality day 7 after the operation and incidence rates of complications were compared between the two groups by t and χ² tests. Results　After the treatment, the white blood cell count, erythrocyte sedimentation rate, and level of C-reactive protein in the observation group were lower than those in the control group [(7.15±1.24)×10⁹/L vs. (9.63±1.15)×10⁹/L, (18.24±2.25) mm/h vs. (25.07±2.23) mm/h, and (38.15±3.03) mg/L vs. (46.17±2.89) mg/L]; the wound red-stage, wound healing time, dressing maintenance time, and postoperative hospital stay in the observation group were shorter than those in the control group [(4.15±1.02) d vs. (8.39±2.15), (14.79±2.48) d vs. (27.34±3.36) d, (8.16±2.07) d vs. (23.76±3.89), and (8.59±2.18) d vs. (16.54±3.57) d]; the total incidence rate of complications in the observation group was lower than that in the control group [6.67% (2/30) vs. 33.3% (10/30)]; the scores of general conditions, mental health, and social function in the observation group were higher than those in the control group (85.27±3.42 vs. 80.15±3.65, 89.35±5.13 vs. 84.20±5.40, and 91.15±5.93 vs. 86.90±6.10); there were statistical differences in the above indicators between the two groups (all P<0.001). Conclusion　Postoperative closed negative pressure wound therapy for patients with chest wall tuberculosis can improve their clinical inflammation-related indicators, alleviate their pain, and reduce their negative emotions, and shorten wound healing time.

Key words: Chest wall tuberculosis, , Closed negative pressure wound therapy, , Wound, , Complications, , Quality of life

江涛肖泽林. 术后应用封闭式负压创面治疗技术促进胸壁结核伤口愈合 [J]. 国际医药卫生导报, 2025, 31(10): 1701-1705.

Jiang Tao, Xiao Zelin.

Postoperative closed negative pressure wound therapy for wound healing in chest wall tuberculosis [J]. International Medicine and Health Guidance News, 2025, 31(10): 1701-1705.

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