关键词:

肩周炎, 瘀血痹片, 温针灸, 肩关节功能, 疼痛介质

Abstract:

Objective　This study aimed to evaluate the effectiveness of Yuxue Bi tablets combined with warm needle acupuncture in improving shoulder function recovery and pain relief in patients with periarthritis of shoulder. Methods　This randomized controlled trial included 83 patients with periarthritis of shoulder treated at the Department of physiotherapy, Yulin Hospital of the First Affiliated Hospital of Xi'an Jiaotong University, from April 2020 to April 2023. The patients were randomly divided into a control group (41 cases) receiving warm needle acupuncture and an observation group (42 cases) receiving Yuxue Bi tablets combined with warm needle acupuncture, using envelope drawing method. The control group included 27 males and 14 females, the age was (55.84±5.21) years old, the course of disease was (7.91±0.91) months, and the position of shoulder periarthritis was on the left side in 17 cases and right side in 24 cases. The observation group included 31 males and 11 females, the age was (55.88±5.15) years old, the course of disease was (7.94±0.93) months, and the position of shoulder periarthritis was on the left side in 15 cases and right side in 27 cases. The clinical efficacy, shoulder joint function [Range of Motion (ROM) score], levels of pain mediators [serum 5-hydroxytryptamine (5-HT), prostaglandin E2 (PGE2), and substance P (SP)], and Traditional Chinese Medicine (TCM) syndrome scores (joint swelling, joint pain, joint aversion to cold, and joint heaviness) were compared between the two groups after 3 courses of treatment. Independent sample t test and χ² test were used. Results　After 3 courses of treatment, the total effective rate of the observation group [92.86% (39/42)] was higher than that of the control group [75.61% (31/41)], with a statistically significant difference (P<0.05). The anterior flexion [(127.97±13.54)°], abduction [(101.60±10.43)°], posterior extension [(36.26±3.67)°], internal rotation [(52.78±4.99)°], and external rotation range [(54.78±5.06)°] in the observation group were higher than those in the control group [(118.14±12.52)°, (90.18±9.58)°, (28.84±3.59)°, (43.82±4.76)°, and (45.82±4.58)°], with statistically significant differences (all P<0.05). The levels of 5-HT [(5.96±0.63) ng/L], PGE2 [(148.06±15.43) ng/L], and SP [(232.91±23.66) mg/L] in the observation group were lower than those in the control group [(9.52±0.94) ng/L, (184.18±18.50) ng/L, and (280.95±28.50) mg/L], with statistically significant differences (all P<0.05). The scores of joint swelling [(0.51±0.05) points], joint pain [(0.65±0.07) points], joint aversion to cold [(0.49±0.05) points], and joint heaviness [(0.89±0.08) points] in the observation group were all lower than those in the control group [(1.33±0.16) points, (1.72±0.14) points, (1.08±0.10) points, and (1.79±0.18) points], with statistically significant differences (all P<0.05). Conclusions　Yuxue Bi tablets combined with warm needle acupuncture can effectively improve the shoulder joint function and TCM symptom scores in patients with periarthritis of shoulder, and lower their pain mediator levels, thereby enhancing the clinical efficacy. This approach shows promising application prospects.

Key words:

Periarthritis of shoulder, Yuxue Bi tablets, Warm needle acupuncture, Shoulder joint function, Pain mediators