国际医药卫生导报 ›› 2023, Vol. 29 ›› Issue (12): 1688-1692.DOI: 10.3760/cma.j.issn.1007-1245.2023.12.014

• 临床研究 • 上一篇    下一篇

高分辨血管壁MRI对鉴别动脉粥样硬化和急性动脉炎的诊断价值

唐雪珂  曲其志  许丹   

  1. 聊城市第三人民医院CT室,聊城 252000

  • 收稿日期:2023-01-24 出版日期:2023-06-15 发布日期:2023-06-26
  • 通讯作者: 唐雪珂,Email: lcsytxk@163.com
  • 基金资助:

    山东省卫生和计划生育委员会面上项目(WS2018187)

Value of vascular wall high-resolution MRI in differential diagnosis of atherosclerosis and acute arteritis

Tang Xueke, Qu Qizhi, Xu Dan   

  1. CT Room, Liaocheng Third People's Hospital, Liaocheng 252000, China

  • Received:2023-01-24 Online:2023-06-15 Published:2023-06-26
  • Contact: Tang Xueke, Email: lcsytxk@163.com
  • Supported by:

    Project of Shandong Health and Family Planning Commission (WS2018187)

摘要:

目的 探究高分辨血管壁磁共振成像(MRI)对鉴别动脉粥样硬化、急性动脉炎的诊断价值。方法 选择2020年10月至2022年10月期间聊城市第三人民医院收治的疑似动脉粥样硬化或急性动脉炎患者共60例,男32例、女28例,年龄32~75岁,其中42例为动脉粥样硬化,18例为急性动脉炎,将动脉粥样硬化纳入粥样硬化组,将急性动脉炎纳入动脉炎组,比较两组一般资料和高分辨血管壁MRI特征,采用t检验与χ2检验。结果 两组患者年龄、高血压、高同型半胱氨酸血症等一般资料比较,差异均有统计学意义(t=10.60,χ2=14.95、4.37,均P<0.05)。两组患者病变血管形态、T1加权成像(T1WI)/T2加权成像(T2WI)信号、病变血管范围、血管壁增厚方式、血管壁强化、深部微小侧支流空(DTFV)等高分辨血管壁MRI特征比较,差异均有统计学意义(χ2=8.74、6.75、7.70、20.68、13.02、25.71,均P<0.05)。根据logistic回归绘制ROC,结果显示多灶性病变、偏心性增厚联合鉴别诊断动脉粥样硬化和急性动脉炎的AUC为0.871(95%CI 0.759~0.944),以0.551为临界值,敏感度、特异度分别为83.33%、77.78%。结论 高分辨血管壁MRI对动脉粥样硬化、急性动脉炎具有较高鉴别诊断价值。

关键词:

动脉粥样硬化, 急性动脉炎, 高分辨血管壁磁共振成像, 鉴别诊断

Abstract:

Objective To investigate the value of vascular wall high-resolution magnetic resonance imaging (MRI) in the differential diagnosis of atherosclerosis and acute arteritis. Methods A total of 60 patients who were suspected of atherosclerosis or acute arteritis and admitted to Liaocheng Third People's Hospital from October 2020 to October 2022 were enrolled, including 42 patients with atherosclerosis (an atherosclerosis group) and 18 patients with acute arteritis (an arteritis group). There were 32 males and 28 females; they were 32-75 years old. The general data and vascular wall high-resolution MRI characteristics of the two groups were compared. t and χ2 tests were applied. Results There were statistical differences in age, hypertension, hyperhomocysteinemia, morphology of diseased vessels, signals on T1 weighted imaging (T1WI)/T2 weighted imaging (T2WI), range of diseased vessels, vessel wall thickening mode, enhanced vascular wall, and deep tiny flow voids (DTFV) between the two groups (t=10.60; χ2=14.95, 4.37, 8.74, 6.75, 7.70, 20.68, 13.02, and 25.71; all P<0.05). The logistic regression receiver operating characteristic curve (ROC) found that the area under curve (AUC) of the combination of multifocal lesions and eccentric thickening in the differential diagnosis of atherosclerosis and acute arteritis was 0.871 (95%CI 0.759-0.944); when the cut-off value was 0.551, the sensitivity and specificity were 83.33% and 77.78%, respectively. Conclusion Vascular wall high-resolution MRI is of high value in the differential diagnosis of atherosclerosis and acute arteritis.

Key words:

Atherosclerosis, Acute arteritis, Vascular wall high-resolution MRI, Differential diagnosis