磁敏感加权血管成像在急性缺血性脑卒中缺血半暗带评估中的应用

doi:10.3760/cma.j.issn.1007-1245.2024.03.007

国际医药卫生导报 ›› 2024, Vol. 30 ›› Issue (3): 386-389.DOI: 10.3760/cma.j.issn.1007-1245.2024.03.007

磁敏感加权血管成像在急性缺血性脑卒中缺血半暗带评估中的应用

周建国¹ 符大勇¹ 孙振虎¹ 马先军² 张芸芸³

¹南京中医药大学连云港附属医院放射科，连云港　222004；²南京中医药大学连云港附属医院脑病科，连云港　222004；³南京中医药大学连云港附属医院心电诊断科，连云港　222004

收稿日期:2023-11-08 出版日期:2024-02-01 发布日期:2024-03-06
通讯作者: 张芸芸，Email：13645132158@163.com
基金资助:
连云港市重点研发计划（社会发展）项目（SF2141）；连云港市第六期“521工程”科研项目（LYG06521202167）

Susceptibility weighted angiography in evaluation of ischemic penumbra in patients with acute ischemic stroke

Zhou Jianguo¹, Fu Dayong¹, Sun Zhenhu¹, Ma Xianjun², Zhang Yunyun³

¹Department of Radiology, Lianyungang Hospital, Nanjing University of Chinese Medicine, Lianyungang 222004, China; ²Department of Encephalopathy, Lianyungang Hospital, Nanjing University of Chinese Medicine, Lianyungang 222004, China; ³Department of ECG Diagnosis, Lianyungang Hospital, Nanjing University of Chinese Medicine, Lianyungang 222004, China

Received:2023-11-08 Online:2024-02-01 Published:2024-03-06
Contact: Zhang Yunyun, Email: 13645132158@163.com
Supported by:
Project of Key Research and Development Program (Social Development) in Lianyungang City (SF2141); Scientific Research Project of Sixth Phase of "Program 521" in Lianyungang City (LYG06521202167)

摘要/Abstract

摘要：

目的　分析磁敏感加权血管成像（SWAN）在急性缺血性脑卒中缺血半暗带部位及范围评估中的临床应用价值。方法　回顾性收集2019年1月至2022年12月在南京中医药大学连云港附属医院行磁共振检查急性期缺血性脑卒中患者25例，男15例，女10例，年龄（55.7±14.4）岁。均行弥散加权成像（DWI）、T2加权液体衰减反转恢复序列（T2 Flair）、SWAN及三维动脉自旋标记（3D ASL）序列检查，将DWI显示高信号区、表观弥散系数（ADC）显示低信号区判定为梗死核心区，分析SWAN序列提示突出血管征（PVS）阳性区域、3D ASL序列提示脑血流量（CBF）低灌注区域分别与梗死核心区间的不匹配范围差异，采用独立样本t检验。结果　SWAN-DWI不匹配区的范围为（2 289.42±721.47）mm²、3D ASL-DWI不匹配区范围为（2 331.59±730.71）mm²，两者差异无统计学意义（t=0.205，P=0.838）。结论　利用磁共振SWAN序列提示的PVS可用于评估急性缺血性脑卒中缺血半暗带部位及范围，为临床治疗方案选择提供影像依据。

关键词:

急性缺血性脑卒中, 缺血半暗带, 磁敏感加权血管成像, 突出血管征, 脑血流量

Abstract:

Objective　To analyze the clinical value of susceptibility weighted angiography (SWAN) in evaluating the location and range of ischemic penumbra (IP) in patients with acute ischemic stroke. Methods　Twenty-five patients with acute ischemic stroke who underwent magnetic resonance imaging examination at Lianyungang Hospital, Nanjing University of Chinese Medicine from January 2019 to December 2022 were selected, including 15 males and 10 females who were (55.7±14.4) years old. The diffusion weighted imaging (DWI), T2 weighted liquid attenuation inversion recovery sequence (T2 Flair), SWAN, and three-dimensional arterial spin labeling (3D ASL) sequences were performed on all the patients. The high signal area displayed on DWI and the low signal area displayed on the apparent diffusion coefficient (ADC) map were determined as the infarct core area. The SWAN sequence was analyzed to indicate the positive area of prominent vascular sign (PVS). The 3D ASL sequence indicates differences in the mismatch range between the low perfusion area of cerebral blood flow (CBF) and the infarct core interval. The independent-sample t test was applied. Results　The mismatch range of SWAN-DWI was (2 289.42±721.47) mm², and that of 3D ASL-DWI was (2 331.59±730.71) mm², with no statistical difference between the two (t=0.205, P=0.838). Conclusion　PVS prompted by magnetic resonance SWAN sequence can be used to evaluate the location and range of IP, and provide image basis for the selection of clinical treatment.

Key words:

Acute ischemic stroke, Ischemic Penumbra, Susceptibility weighted angiography, Prominent vessel sign, Cerebral blood flow

周建国符大勇孙振虎马先军张芸芸.

磁敏感加权血管成像在急性缺血性脑卒中缺血半暗带评估中的应用 [J]. 国际医药卫生导报, 2024, 30(3): 386-389.

Zhou Jianguo, Fu Dayong, Sun Zhenhu, Ma Xianjun, Zhang Yunyun.

Susceptibility weighted angiography in evaluation of ischemic penumbra in patients with acute ischemic stroke [J]. International Medicine and Health Guidance News, 2024, 30(3): 386-389.

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磁敏感加权血管成像在急性缺血性脑卒中缺血半暗带评估中的应用

Susceptibility weighted angiography in evaluation of ischemic penumbra in patients with acute ischemic stroke

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