关键词:

手术冲洗液, 保存时间, 恒温, 安全性

Abstract:

Objective　To investigate the effect of 38 ℃ thermostatic storage time on the safety of three surgical flushers. Methods　In January 2022, Haikou Hospital Affiliated to Xiangya Medical College, Zhongnan University purchased 0.9% sodium chloride solution in bags, electrocutting solution in bags, and other exhalative solution in bags 480 bags for each as the research objects of this experiment. Four hundred and eighty bags of each of the three surgical flushing solutions were randomly divided into 6 groups. One group was stored at room temperature (21～25 ℃) for 7 days for safety index detection and was set as a blank control group; the other five groups were stored at 38 ℃ for 2, 7, 14, 21, and 28 days, respectively, for safety index detection. One-way analysis of variance was used to compare the data between the groups. Results　The pH values and osmolal pressures of 0.9% sodium chloride solution in the 2, 7, 14, 21, and 28-day heating groups were higher than those in the blank control group, with statistical differences between the groups (F=2.46 and 2.84; both P<0.05). The pH values and osmotic pressure molar concentrations of electrolysis solution in the 2, 7, 14, 21, and 28-day heating groups were higher than those in the blank control group, with statistical differences between the groups (F=6.41 and 14.32; both P<0.05). The pH values and osmotic pressure molar concentrations of exudative solution in the 2, 7, 14, 21, and 28-day heating groups were higher than those in the blank control group, with statistical differences between the groups (F=9.07 and 14.91; both P<0.05). The bacteria culture was negative in all the 3 fluids in the blank control group and the 2, 7, 14, 21, and 28-day heating groups; the appearance of the 3 fluids had no obvious changes; no stratification, turbidity, precipitation, wall hanging, or abnormal odor were found in the 3 fluids. Conclusions　After being stored at 38 ℃ for 28 days, the pH values and osmotic pressure molar concentrations of 9% sodium chloride solution, bag electrolysis solution, and bag exudative solution increased, but all of them were within the safe ranges. At the same time, the three kinds of rinsing solution can maintain the aseptic state, without any stratification, turbidity, precipitation, wall hanging, and abnormal odor, so they can be used safely in clinic.

Key words:

Surgical flushing solution, Storage time, Constant temperature, Safety